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KCNQ5 KCNQ5 KCNH6 KCNH6 KCND3 KCND3 KCNH5 KCNH5 KCNAB3 KCNAB3 KCNAB2 KCNAB2 KCNH1 KCNH1 KCNA1 KCNA1 AKAP9 AKAP9 KCNAB1 KCNAB1 DPP10 DPP10 KCNQ4 KCNQ4 KCNQ3 KCNQ3 KCNC1 KCNC1 KCND2 KCND2 KCNG3 KCNG3 Kcnj13 Kcnj13 KCNIP1 KCNIP1 KCNIP3 KCNIP3 KCNQ1 KCNQ1 Kcnj12 Kcnj12 KCNJ14 KCNJ14 KCNJ4 KCNJ4 KCNH2 KCNH2 KCNF1 KCNF1 KCNK5 KCNK5 KCNA5 KCNA5 KCNH7 KCNH7 KCNIP2 KCNIP2 KCNE2 KCNE2 KCNA6 KCNA6 KCNE3 KCNE3 KCNK16 KCNK16 KCNE1 KCNE1 KCNQ2 KCNQ2 KCNA4 KCNA4 AKR7L AKR7L KCNIP4 KCNIP4 KCNA2 KCNA2 KCNE4 KCNE4 Kcnj2 Kcnj2 DPP6 DPP6 KCND1 KCND1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (908 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (916 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (989 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
KCNH1Uncharacterized protein. (989 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
AKAP9A-kinase anchoring protein 9. (3887 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (776 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa)
Kcnj13Inward rectifier potassium channel 13; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependen [...] (352 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
Kcnj12Uncharacterized protein. (535 aa)
KCNJ14Inwardly-rectifying potassium channel Kir2.4. (439 aa)
KCNJ4Uncharacterized protein. (443 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (435 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (458 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1173 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (491 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
AKR7LAldo-keto reductase family 7 like (gene/pseudogene). (367 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (143 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (174 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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