STRINGSTRING
ALDH6A1 ALDH6A1 AASDH AASDH PNPLA4 PNPLA4 SDR16C5 SDR16C5 Rdh10 Rdh10 RDH12 RDH12 AUH AUH MLYCD MLYCD DHRS7 DHRS7 ACAD10 ACAD10 DHRS3 DHRS3 ACAT2 ACAT2 Hpgd Hpgd ECI1 ECI1 FASN FASN PEX5L PEX5L Rdh11 Rdh11 ALDH16A1 ALDH16A1 LOC100717492 LOC100717492 HSDL2 HSDL2 ALDH1A2 ALDH1A2 CRYL1 CRYL1 ACSS3 ACSS3 DIP2A DIP2A LONP2 LONP2 LOC100730233 LOC100730233 ACSM5 ACSM5 SLC34A1 SLC34A1 RBP2 RBP2 ACSS2 ACSS2 ETFDH ETFDH ACACB ACACB ACAA2 ACAA2 ECI2 ECI2 HADHB HADHB ABHD10 ABHD10 LOC100719714 LOC100719714 MCCC2 MCCC2 HADHA HADHA DHRS9 DHRS9 ACACA ACACA ETFA ETFA TYSND1 TYSND1 HMGCS2 HMGCS2 ALDH1L1 ALDH1L1 DECR2 DECR2 ACOX2 ACOX2 PALB2 PALB2 FAM185A FAM185A ALDH8A1 ALDH8A1 PYROXD2 PYROXD2 LOC100732008 LOC100732008 RTN4IP1 RTN4IP1 C1orf146 C1orf146 LOC100732696 LOC100732696 AACS AACS DHRS13 DHRS13 PHYH PHYH H0VAK6_CAVPO H0VAK6_CAVPO VAT1L VAT1L HLCS HLCS HMGCL HMGCL ACSM3 ACSM3 AMACR AMACR RLBP1 RLBP1 ACOT12 ACOT12 SLC34A3 SLC34A3 ACADL ACADL MRTFA MRTFA BCO2 BCO2 LOC100713989 LOC100713989 HSD17B4 HSD17B4 Olah Olah ALDH1L2 ALDH1L2 MCCC1 MCCC1 ACADM ACADM PCCA PCCA CPT2 CPT2 PECR PECR ECHS1 ECHS1 DIP2B DIP2B ACADSB ACADSB CAT CAT AKR1A1 AKR1A1 ACSF3 ACSF3 RPE65 RPE65 DEPDC1 DEPDC1 HSD17B8 HSD17B8 DHRS1 DHRS1 BCO1 BCO1 ACAT1 ACAT1 ACOX1 ACOX1 ACADS ACADS ALDH3A1 ALDH3A1 CYP26A1 CYP26A1 FADS3 FADS3 ACADVL ACADVL H0VW66_CAVPO H0VW66_CAVPO HSD17B1 HSD17B1 RDH8 RDH8 HADH HADH Aox4 Aox4 SLC34A2 SLC34A2 H0W0J6_CAVPO H0W0J6_CAVPO ACSM4 ACSM4 MCAT MCAT H0W3W9_CAVPO H0W3W9_CAVPO LOC100734190 LOC100734190 HIBADH HIBADH LOC100735818 LOC100735818 ACOX3 ACOX3 ALDH3B1 ALDH3B1 OXCT2 OXCT2 IVD IVD VAT1 VAT1 ACAD11 ACAD11 Phyhd1 Phyhd1 RDH5 RDH5 OXSM OXSM PEX5 PEX5 GCDH GCDH H0WCC9_CAVPO H0WCC9_CAVPO Aox1 Aox1 CARTPT CARTPT OXCT1 OXCT1 RDH16 RDH16 ALDH3A2 ALDH3A2 ENSCPOP00000022046 ENSCPOP00000022046 DHRS7B DHRS7B ABHD11 ABHD11 PEX2 PEX2 LOC100723257 LOC100723257 BDH2 BDH2 Echdc1 Echdc1 ILVBL ILVBL ENSCPOP00000024929 ENSCPOP00000024929 CENPV CENPV PC PC C15orf41 C15orf41 Adhfe1 Adhfe1 PEX7 PEX7 EHHADH EHHADH Acaa1 Acaa1 ACLY ACLY Aldh2 Aldh2 LRAT LRAT PCCB PCCB LOC100727028 LOC100727028 RDH14 RDH14 CYP4V2 CYP4V2 ACSM1 ACSM1 DHRS11 DHRS11 ADH5 ADH5 HTD2 HTD2 HIBCH HIBCH ESD ESD ETFB ETFB EPHX2 EPHX2 UBAP2 UBAP2 AASDHPPT AASDHPPT BDH1 BDH1 LOC100732581 LOC100732581 ACAD8 ACAD8 ENSCPOP00000031385 ENSCPOP00000031385 ECHDC2 ECHDC2 CBR4 CBR4 ENSCPOP00000032185 ENSCPOP00000032185 LOC100727518 LOC100727518 LOC100732853 LOC100732853 DIP2C DIP2C
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (533 aa)
AASDHAminoadipate-semialdehyde dehydrogenase. (1088 aa)
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
Rdh10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
DHRS7Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (450 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1059 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
Hpgd15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
FASNFatty acid synthase. (2530 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (650 aa)
Rdh11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (804 aa)
LOC100717492Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
HSDL2Hydroxysteroid dehydrogenase like 2. (440 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa)
CRYL1Crystallin lambda 1. (319 aa)
ACSS3Acyl-CoA synthetase short chain family member 3. (682 aa)
DIP2ADisco interacting protein 2 homolog A. (1549 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
LOC100730233Uncharacterized protein. (577 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (579 aa)
SLC34A1Solute carrier family 34 member 1. (638 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (713 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
ACACBAcetyl-CoA carboxylase beta. (2447 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ECI2Enoyl-CoA delta isomerase 2. (354 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (487 aa)
ABHD10Abhydrolase domain containing 10. (302 aa)
LOC100719714Uncharacterized protein. (279 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
ACACAAcetyl-CoA carboxylase alpha. (2393 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
TYSND1Trypsin domain containing 1. (570 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
ALDH1L110-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (902 aa)
DECR22,4-dienoyl-CoA reductase 2. (292 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
PALB2Partner and localizer of BRCA2. (1172 aa)
FAM185AFamily with sequence similarity 185 member A. (388 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
PYROXD2Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa)
LOC100732008PKS_ER domain-containing protein. (375 aa)
RTN4IP1Reticulon 4 interacting protein 1. (396 aa)
C1orf146Chromosome 1 open reading frame 146. (153 aa)
LOC100732696Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
DHRS13Dehydrogenase/reductase 13. (378 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (336 aa)
H0VAK6_CAVPOUncharacterized protein. (177 aa)
VAT1LVesicle amine transport 1 like. (414 aa)
HLCSHolocarboxylase synthetase. (868 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
ACSM3Acyl-CoA synthetase medium chain family member 3. (585 aa)
AMACRAlpha-methylacyl-CoA racemase. (383 aa)
RLBP1Retinaldehyde binding protein 1. (317 aa)
ACOT12Acyl-CoA thioesterase 12. (548 aa)
SLC34A3Solute carrier family 34 member 3. (539 aa)
ACADLAcyl-CoA dehydrogenase long chain. (432 aa)
MRTFAMyocardin related transcription factor A. (791 aa)
BCO2Beta-carotene oxygenase 2. (532 aa)
LOC100713989Uncharacterized protein. (621 aa)
HSD17B4Uncharacterized protein. (713 aa)
OlahOleoyl-ACP hydrolase. (265 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (363 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (728 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4- dienoyl-CoA reductase activity. (302 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
DIP2BDisco interacting protein 2 homolog B. (1486 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (424 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (325 aa)
ACSF3Acyl-CoA synthetase family member 3. (598 aa)
RPE65Retinoid isomerohydrolase RPE65. (490 aa)
DEPDC1DEP domain containing 1. (527 aa)
HSD17B8Hydroxysteroid 17-beta dehydrogenase 8. (259 aa)
DHRS1Dehydrogenase/reductase 1. (313 aa)
BCO1Beta-carotene oxygenase 1. (557 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ACOX1Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (660 aa)
ACADSAcyl-CoA dehydrogenase short chain. (413 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
FADS3Fatty acid desaturase 3. (441 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (633 aa)
H0VW66_CAVPOUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
HSD17B1Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
HADHHydroxyacyl-CoA dehydrogenase. (313 aa)
Aox4Aldehyde oxidase 4; Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity); Belongs to the xanthine dehydrogenase family. (1341 aa)
SLC34A2Solute carrier family 34 member 2. (749 aa)
H0W0J6_CAVPOUncharacterized protein. (384 aa)
ACSM4Acyl-CoA synthetase medium chain family member 4. (578 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (387 aa)
H0W3W9_CAVPOUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (329 aa)
LOC100734190Uncharacterized protein. (369 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase. (293 aa)
LOC100735818Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (737 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
OXCT2Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (503 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
VAT1Vesicle amine transport 1. (389 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (806 aa)
Phyhd1Uncharacterized protein. (287 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
GCDHGlutaryl-CoA dehydrogenase. (414 aa)
H0WCC9_CAVPOUncharacterized protein. (384 aa)
Aox1Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen specie [...] (1329 aa)
CARTPTCART prepropeptide. (129 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
DHRS7BDehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
ABHD11Abhydrolase domain containing 11. (307 aa)
PEX2Peroxisomal biogenesis factor 2. (304 aa)
LOC100723257Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
Echdc1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (301 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (634 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
CENPVCentromere protein V. (166 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1219 aa)
C15orf41Chromosome 15 open reading frame 41. (281 aa)
Adhfe1Fe-ADH domain-containing protein. (466 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
EHHADHEnoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
Acaa1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa)
Aldh2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa)
LRATLecithin retinol acyltransferase. (230 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (539 aa)
LOC100727028PKS_ER domain-containing protein. (382 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (524 aa)
ACSM1Acyl-CoA synthetase medium chain family member 1. (524 aa)
DHRS11Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (367 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (158 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
EPHX2Epoxide hydrolase 2. (469 aa)
UBAP2Ubiquitin associated protein 2. (1123 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (344 aa)
LOC100732581Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (414 aa)
ENSCPOP00000031385annotation not available (138 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
CBR4Carbonyl reductase 4. (237 aa)
ENSCPOP00000032185Aldedh domain-containing protein. (166 aa)
LOC100727518PKS_ER domain-containing protein. (213 aa)
LOC100732853Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
DIP2CDisco interacting protein 2 homolog C. (1551 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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