STRINGSTRING
PNPLA4 PNPLA4 SDR16C5 SDR16C5 Rdh10 Rdh10 RDH12 RDH12 DHRS3 DHRS3 Hpgd Hpgd Rdh11 Rdh11 LOC100717492 LOC100717492 ALDH1A2 ALDH1A2 RBP2 RBP2 LOC100719714 LOC100719714 DHRS9 DHRS9 ALDH8A1 ALDH8A1 PYROXD2 PYROXD2 LOC100732008 LOC100732008 DHRS13 DHRS13 RLBP1 RLBP1 MRTFA MRTFA BCO2 BCO2 AKR1A1 AKR1A1 RPE65 RPE65 DEPDC1 DEPDC1 BCO1 BCO1 ALDH3A1 ALDH3A1 CYP26A1 CYP26A1 FADS3 FADS3 H0VW66_CAVPO H0VW66_CAVPO RDH8 RDH8 Aox4 Aox4 H0W0J6_CAVPO H0W0J6_CAVPO LOC100734190 LOC100734190 LOC100735818 LOC100735818 ALDH3B1 ALDH3B1 VAT1 VAT1 RDH5 RDH5 H0WCC9_CAVPO H0WCC9_CAVPO Aox1 Aox1 RDH16 RDH16 ILVBL ILVBL CENPV CENPV Adhfe1 Adhfe1 Aldh2 Aldh2 LRAT LRAT LOC100727028 LOC100727028 RDH14 RDH14 ADH5 ADH5 ESD ESD LOC100732581 LOC100732581 ENSCPOP00000032185 ENSCPOP00000032185 LOC100732853 LOC100732853
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
Rdh10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
Hpgd15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
Rdh11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
LOC100717492Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
LOC100719714Uncharacterized protein. (279 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
PYROXD2Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa)
LOC100732008PKS_ER domain-containing protein. (375 aa)
DHRS13Dehydrogenase/reductase 13. (378 aa)
RLBP1Retinaldehyde binding protein 1. (317 aa)
MRTFAMyocardin related transcription factor A. (791 aa)
BCO2Beta-carotene oxygenase 2. (532 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (325 aa)
RPE65Retinoid isomerohydrolase RPE65. (490 aa)
DEPDC1DEP domain containing 1. (527 aa)
BCO1Beta-carotene oxygenase 1. (557 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
FADS3Fatty acid desaturase 3. (441 aa)
H0VW66_CAVPOUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
Aox4Aldehyde oxidase 4; Aldehyde oxidase able to catalyze the oxidation of retinaldehyde into retinoate. Acts as a negative modulator of the epidermal trophism. May be able to oxidize a wide variety of aldehydes into their corresponding carboxylates and to hydroxylate azaheterocycles (By similarity); Belongs to the xanthine dehydrogenase family. (1341 aa)
H0W0J6_CAVPOUncharacterized protein. (384 aa)
LOC100734190Uncharacterized protein. (369 aa)
LOC100735818Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
VAT1Vesicle amine transport 1. (389 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
H0WCC9_CAVPOUncharacterized protein. (384 aa)
Aox1Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen specie [...] (1329 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (634 aa)
CENPVCentromere protein V. (166 aa)
Adhfe1Fe-ADH domain-containing protein. (466 aa)
Aldh2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa)
LRATLecithin retinol acyltransferase. (230 aa)
LOC100727028PKS_ER domain-containing protein. (382 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (367 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
LOC100732581Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa)
ENSCPOP00000032185Aldedh domain-containing protein. (166 aa)
LOC100732853Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.