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Bckdha Bckdha IDH3A IDH3A SUCLG1 SUCLG1 PDHX PDHX OGDH OGDH ACO1 ACO1 Dld Dld PDHB PDHB DBT DBT TXNRD3 TXNRD3 DHTKD1 DHTKD1 IDH2 IDH2 Pdha1 Pdha1 Dlst Dlst IDH1 IDH1 CS CS SUCLA2 SUCLA2 IDH3B IDH3B OGDHL OGDHL H0WAF5_CAVPO H0WAF5_CAVPO IDH3G IDH3G ACO2 ACO2 BCKDHB BCKDHB ENSCPOP00000026353 ENSCPOP00000026353 DLAT DLAT ENSCPOP00000032995 ENSCPOP00000032995
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (442 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
DldDihydrolipoyl dehydrogenase. (509 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
TXNRD3Thioredoxin reductase 3. (612 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (920 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
DlstLipoyl-binding domain-containing protein. (440 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (457 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa)
OGDHLOxoglutarate dehydrogenase like. (1022 aa)
H0WAF5_CAVPOIso_dh domain-containing protein. (332 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
ENSCPOP00000026353Dihydrolipoyl dehydrogenase. (501 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (650 aa)
ENSCPOP00000032995Lipoyl-binding domain-containing protein. (440 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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