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GBA2 GBA2 CERS5 CERS5 CERS2 CERS2 SGPP2 SGPP2 SMPD1 SMPD1 SMPD2 SMPD2 GBA GBA ASAH1 ASAH1 DEGS1 DEGS1 SMPDL3B SMPDL3B UGCG UGCG H0VER4_CAVPO H0VER4_CAVPO SPHK1 SPHK1 ASAH2 ASAH2 SGMS1 SGMS1 ACER1 ACER1 CERS4 CERS4 PLPP2 PLPP2 CERK CERK DEGS2 DEGS2 CERS6 CERS6 SGPP1 SGPP1 SGPL1 SGPL1 KDSR KDSR SPHK2 SPHK2 ENSCPOP00000026943 ENSCPOP00000026943 SGMS2 SGMS2 ACER2 ACER2 SMPD4 SMPD4 ACER3 ACER3 SMPD3 SMPD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (908 aa)
CERS5Ceramide synthase 5. (428 aa)
CERS2Ceramide synthase 2. (380 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (354 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (430 aa)
GBAGlucosylceramidase. (516 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (457 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (393 aa)
H0VER4_CAVPODAGKc domain-containing protein. (277 aa)
SPHK1Sphingosine kinase 1. (386 aa)
ASAH2Neutral ceramidase. (752 aa)
SGMS1Sphingomyelin synthase 1. (413 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa)
CERS4Ceramide synthase 4. (391 aa)
PLPP2Phospholipid phosphatase 2. (260 aa)
CERKCeramide kinase. (483 aa)
DEGS2Delta 4-desaturase, sphingolipid 2. (315 aa)
CERS6Ceramide synthase 6. (392 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (407 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
SPHK2Sphingosine kinase 2. (655 aa)
ENSCPOP00000026943TLC domain-containing protein. (287 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (823 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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