(15 nodes) Processing of SMDT1, and Rhomboid serine protease network (Cavia porcellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PHB	Prohibitin. (272 aa)
	LOC100733451	AAA domain-containing protein. (805 aa)
	STOML1	Stomatin like 1. (406 aa)
	BCS1L	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (418 aa)
	SPG7	SPG7 matrix AAA peptidase subunit, paraplegin. (802 aa)
	MAIP1	Matrix AAA peptidase interacting protein 1. (273 aa)
	RHBDF1	Rhomboid 5 homolog 1. (891 aa)
	RHBDF2	Rhomboid 5 homolog 2. (824 aa)
	STOML2	Stomatin like 2. (356 aa)
	Parl	Rhomboid domain-containing protein. (379 aa)
	RHBDL2	Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (302 aa)
	PHB2	Prohibitin. (299 aa)
	AFG3L2	AFG3 like matrix AAA peptidase subunit 2. (809 aa)
	LOC101789248	Peptidase_M41 domain-containing protein. (160 aa)
	STOM	Stomatin. (284 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	LOC100733451	ENSCPOP00000027150	ENSCPOP00000001028	AFG3 like matrix AAA peptidase subunit 2.	AAA domain-containing protein.	0.884
AFG3L2	LOC101789248	ENSCPOP00000027150	ENSCPOP00000028700	AFG3 like matrix AAA peptidase subunit 2.	Peptidase_M41 domain-containing protein.	0.470
AFG3L2	MAIP1	ENSCPOP00000027150	ENSCPOP00000003430	AFG3 like matrix AAA peptidase subunit 2.	Matrix AAA peptidase interacting protein 1.	0.683
AFG3L2	PHB	ENSCPOP00000027150	ENSCPOP00000000380	AFG3 like matrix AAA peptidase subunit 2.	Prohibitin.	0.930
AFG3L2	PHB2	ENSCPOP00000027150	ENSCPOP00000018339	AFG3 like matrix AAA peptidase subunit 2.	Prohibitin.	0.916
AFG3L2	Parl	ENSCPOP00000027150	ENSCPOP00000012613	AFG3 like matrix AAA peptidase subunit 2.	Rhomboid domain-containing protein.	0.782
AFG3L2	RHBDF1	ENSCPOP00000027150	ENSCPOP00000005669	AFG3 like matrix AAA peptidase subunit 2.	Rhomboid 5 homolog 1.	0.420
AFG3L2	RHBDF2	ENSCPOP00000027150	ENSCPOP00000008873	AFG3 like matrix AAA peptidase subunit 2.	Rhomboid 5 homolog 2.	0.420
AFG3L2	RHBDL2	ENSCPOP00000027150	ENSCPOP00000017958	AFG3 like matrix AAA peptidase subunit 2.	Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.420
AFG3L2	SPG7	ENSCPOP00000027150	ENSCPOP00000002810	AFG3 like matrix AAA peptidase subunit 2.	SPG7 matrix AAA peptidase subunit, paraplegin.	0.867
AFG3L2	STOM	ENSCPOP00000027150	ENSCPOP00000029254	AFG3 like matrix AAA peptidase subunit 2.	Stomatin.	0.792
AFG3L2	STOML1	ENSCPOP00000027150	ENSCPOP00000002193	AFG3 like matrix AAA peptidase subunit 2.	Stomatin like 1.	0.817
AFG3L2	STOML2	ENSCPOP00000027150	ENSCPOP00000010827	AFG3 like matrix AAA peptidase subunit 2.	Stomatin like 2.	0.795
BCS1L	MAIP1	ENSCPOP00000002315	ENSCPOP00000003430	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Matrix AAA peptidase interacting protein 1.	0.613
BCS1L	PHB	ENSCPOP00000002315	ENSCPOP00000000380	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Prohibitin.	0.803
BCS1L	PHB2	ENSCPOP00000002315	ENSCPOP00000018339	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Prohibitin.	0.811
BCS1L	Parl	ENSCPOP00000002315	ENSCPOP00000012613	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Rhomboid domain-containing protein.	0.420
BCS1L	RHBDF1	ENSCPOP00000002315	ENSCPOP00000005669	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Rhomboid 5 homolog 1.	0.420
BCS1L	RHBDF2	ENSCPOP00000002315	ENSCPOP00000008873	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Rhomboid 5 homolog 2.	0.420
BCS1L	RHBDL2	ENSCPOP00000002315	ENSCPOP00000017958	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.	Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.420