17 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	OSGEPL1	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (414 aa)
	TP53RK	TP53 regulating kinase. (246 aa)
	CCDC58	Coiled-coil domain containing 58. (144 aa)
	BCCIP	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
	ZZEF1	Zinc finger ZZ-type and EF-hand domain containing 1. (2961 aa)
	ANO5	Anoctamin. (886 aa)
	OSGEP	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (335 aa)
	H0W2Q7_CAVPO	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (150 aa)
	Nop16	Uncharacterized protein. (181 aa)
	Lage3	Uncharacterized protein. (119 aa)
	GON7	GON7 subunit of KEOPS complex. (102 aa)
	Tprkb	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (175 aa)
	CCDC59	Coiled-coil domain containing 59. (238 aa)
	LLPH	LLP homolog, long-term synaptic facilitation factor. (128 aa)
	TMEM260	Transmembrane protein 260. (712 aa)
	YRDC	YrdC N6-threonylcarbamoyltransferase domain containing. (279 aa)
	TMEM126A	Transmembrane protein 126A. (195 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANO5	CCDC58	ENSCPOP00000012563	ENSCPOP00000005149	Anoctamin.	Coiled-coil domain containing 58.	0.437
ANO5	ZZEF1	ENSCPOP00000012563	ENSCPOP00000006721	Anoctamin.	Zinc finger ZZ-type and EF-hand domain containing 1.	0.437
BCCIP	LLPH	ENSCPOP00000005801	ENSCPOP00000030424	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	LLP homolog, long-term synaptic facilitation factor.	0.694
BCCIP	Nop16	ENSCPOP00000005801	ENSCPOP00000017938	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Uncharacterized protein.	0.750
CCDC58	ANO5	ENSCPOP00000005149	ENSCPOP00000012563	Coiled-coil domain containing 58.	Anoctamin.	0.437
CCDC58	CCDC59	ENSCPOP00000005149	ENSCPOP00000029628	Coiled-coil domain containing 58.	Coiled-coil domain containing 59.	0.583
CCDC58	LLPH	ENSCPOP00000005149	ENSCPOP00000030424	Coiled-coil domain containing 58.	LLP homolog, long-term synaptic facilitation factor.	0.416
CCDC58	TMEM126A	ENSCPOP00000005149	ENSCPOP00000032498	Coiled-coil domain containing 58.	Transmembrane protein 126A.	0.595
CCDC58	ZZEF1	ENSCPOP00000005149	ENSCPOP00000006721	Coiled-coil domain containing 58.	Zinc finger ZZ-type and EF-hand domain containing 1.	0.581
CCDC59	CCDC58	ENSCPOP00000029628	ENSCPOP00000005149	Coiled-coil domain containing 59.	Coiled-coil domain containing 58.	0.583
CCDC59	LLPH	ENSCPOP00000029628	ENSCPOP00000030424	Coiled-coil domain containing 59.	LLP homolog, long-term synaptic facilitation factor.	0.897
GON7	H0W2Q7_CAVPO	ENSCPOP00000025177	ENSCPOP00000017251	GON7 subunit of KEOPS complex.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.586
GON7	Lage3	ENSCPOP00000025177	ENSCPOP00000024932	GON7 subunit of KEOPS complex.	Uncharacterized protein.	0.988
GON7	OSGEP	ENSCPOP00000025177	ENSCPOP00000013026	GON7 subunit of KEOPS complex.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.989
GON7	OSGEPL1	ENSCPOP00000025177	ENSCPOP00000004252	GON7 subunit of KEOPS complex.	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.	0.915
GON7	TP53RK	ENSCPOP00000025177	ENSCPOP00000004932	GON7 subunit of KEOPS complex.	TP53 regulating kinase.	0.956
GON7	Tprkb	ENSCPOP00000025177	ENSCPOP00000028771	GON7 subunit of KEOPS complex.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.723
H0W2Q7_CAVPO	GON7	ENSCPOP00000017251	ENSCPOP00000025177	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	GON7 subunit of KEOPS complex.	0.586
H0W2Q7_CAVPO	Lage3	ENSCPOP00000017251	ENSCPOP00000024932	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	Uncharacterized protein.	0.926
H0W2Q7_CAVPO	OSGEP	ENSCPOP00000017251	ENSCPOP00000013026	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.983