5 items (Cavia porcellus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	TP53RK	TP53 regulating kinase. (246 aa)
	OSGEP	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (335 aa)
	Lage3	Uncharacterized protein. (119 aa)
	GON7	GON7 subunit of KEOPS complex. (102 aa)
	Tprkb	Uncharacterized protein; Belongs to the CGI121/TPRKB family. (175 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GON7	Lage3	ENSCPOP00000025177	ENSCPOP00000024932	GON7 subunit of KEOPS complex.	Uncharacterized protein.	0.988
GON7	OSGEP	ENSCPOP00000025177	ENSCPOP00000013026	GON7 subunit of KEOPS complex.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.989
GON7	TP53RK	ENSCPOP00000025177	ENSCPOP00000004932	GON7 subunit of KEOPS complex.	TP53 regulating kinase.	0.956
GON7	Tprkb	ENSCPOP00000025177	ENSCPOP00000028771	GON7 subunit of KEOPS complex.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.723
Lage3	GON7	ENSCPOP00000024932	ENSCPOP00000025177	Uncharacterized protein.	GON7 subunit of KEOPS complex.	0.988
Lage3	OSGEP	ENSCPOP00000024932	ENSCPOP00000013026	Uncharacterized protein.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.998
Lage3	TP53RK	ENSCPOP00000024932	ENSCPOP00000004932	Uncharacterized protein.	TP53 regulating kinase.	0.956
Lage3	Tprkb	ENSCPOP00000024932	ENSCPOP00000028771	Uncharacterized protein.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.926
OSGEP	GON7	ENSCPOP00000013026	ENSCPOP00000025177	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	GON7 subunit of KEOPS complex.	0.989
OSGEP	Lage3	ENSCPOP00000013026	ENSCPOP00000024932	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Uncharacterized protein.	0.998
OSGEP	TP53RK	ENSCPOP00000013026	ENSCPOP00000004932	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	TP53 regulating kinase.	0.999
OSGEP	Tprkb	ENSCPOP00000013026	ENSCPOP00000028771	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.989
TP53RK	GON7	ENSCPOP00000004932	ENSCPOP00000025177	TP53 regulating kinase.	GON7 subunit of KEOPS complex.	0.956
TP53RK	Lage3	ENSCPOP00000004932	ENSCPOP00000024932	TP53 regulating kinase.	Uncharacterized protein.	0.956
TP53RK	OSGEP	ENSCPOP00000004932	ENSCPOP00000013026	TP53 regulating kinase.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.999
TP53RK	Tprkb	ENSCPOP00000004932	ENSCPOP00000028771	TP53 regulating kinase.	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	0.992
Tprkb	GON7	ENSCPOP00000028771	ENSCPOP00000025177	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	GON7 subunit of KEOPS complex.	0.723
Tprkb	Lage3	ENSCPOP00000028771	ENSCPOP00000024932	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	Uncharacterized protein.	0.926
Tprkb	OSGEP	ENSCPOP00000028771	ENSCPOP00000013026	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.	0.989
Tprkb	TP53RK	ENSCPOP00000028771	ENSCPOP00000004932	Uncharacterized protein; Belongs to the CGI121/TPRKB family.	TP53 regulating kinase.	0.992