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| | H0W0U4_CAVPO | Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (420 aa) |
| | HSPD1 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (574 aa) |
| | PRDX2 | Peroxiredoxin 2. (198 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | ATP7A | ATPase copper transporting alpha. (1433 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (482 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) |
| | HSF1 | Heat shock transcription factor 1. (555 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (749 aa) |
| | FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (569 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (656 aa) |
| | SETX | Senataxin. (2661 aa) |
| | H0UWK8_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (250 aa) |
| | BECN1 | Beclin 1. (448 aa) |
| | MB | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1473 aa) |
| | BTK | Tyrosine-protein kinase. (659 aa) |
| | SIGMAR1 | Sigma non-opioid intracellular receptor 1; Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. [...] (223 aa) |
| | ADPRHL2 | ADP-ribosylhydrolase like 2. (367 aa) |
| | CASP6 | Caspase 6; Belongs to the peptidase C14A family. (279 aa) |
| | ENSCPOP00000030888 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa) |
| | PLEKHA1 | Pleckstrin homology domain containing A1. (402 aa) |
| | ZNF277 | Zinc finger protein 277. (473 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (614 aa) |
| | BNIP3 | BCL2 interacting protein 3. (194 aa) |
| | CRYAB | AlphaB-crystallin; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa) |
| | GLRX2 | Glutaredoxin 2. (160 aa) |
| | ENSCPOP00000029431 | Uncharacterized protein. (111 aa) |
| | UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa) |
| | APTX | Aprataxin. (341 aa) |
| | PPARGC1B | PPARG coactivator 1 beta. (1028 aa) |
| | UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (646 aa) |
| | H0UY86_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (213 aa) |
| | ENSCPOP00000029129 | Protein kinase domain-containing protein. (254 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa) |
| | Rps3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1344 aa) |
| | LOC106027874 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (209 aa) |
| | LOC100722819 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (223 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (591 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (633 aa) |
| | PRDX1 | Peroxiredoxin 1. (199 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | ENSCPOP00000026628 | Uncharacterized protein. (100 aa) |
| | LOC100718490 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (198 aa) |
| | STK26 | Serine/threonine kinase 26. (410 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1454 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (747 aa) |
| | ENSCPOP00000026239 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (223 aa) |
| | CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (714 aa) |
| | APOD | Apolipoprotein D; APOD occurs in the macromolecular complex with lecithin- transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (189 aa) |
| | H0V2A5_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (237 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa) |
| | OSER1 | Oxidative stress responsive serine rich 1. (292 aa) |
| | HDAC6 | Histone deacetylase 6. (1196 aa) |
| | AGAP3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (853 aa) |
| | FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | Lig1 | DNA ligase. (909 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1903 aa) |
| | FXN | Frataxin. (211 aa) |
| | NOS3 | Nitric oxide synthase, endothelial; Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets (By similarity); Belongs to the NOS family. (1206 aa) |
| | KDM6B | Lysine demethylase 6B. (1467 aa) |
| | ANKZF1 | Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (722 aa) |
| | ECT2 | Epithelial cell transforming 2. (913 aa) |
| | HYAL2 | Hyaluronidase. (471 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (828 aa) |
| | Cdk1 | Protein kinase domain-containing protein. (240 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | LOC100725465 | FABP domain-containing protein. (127 aa) |
| | Bad | Uncharacterized protein. (166 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (874 aa) |
| | PPP1R15B | Protein phosphatase 1 regulatory subunit 15B. (702 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa) |
| | PLD2 | Phospholipase. (936 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (281 aa) |
| | LOC100725733 | FABP domain-containing protein. (127 aa) |
| | MMP9 | Matrix metallopeptidase 9. (715 aa) |
| | OPTN | Optineurin. (576 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (853 aa) |
| | AXL | AXL receptor tyrosine kinase. (888 aa) |
| | H0VDE6_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (196 aa) |
| | LOC100726004 | FABP domain-containing protein. (127 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | NME8 | NME/NM23 family member 8. (553 aa) |
| | AMBP | Uncharacterized protein. (352 aa) |
| | KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (558 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (789 aa) |
| | TXNRD2 | Uncharacterized protein. (524 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1455 aa) |
| | Aqp1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | Trpa1 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (991 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | SPHK1 | Sphingosine kinase 1. (386 aa) |
| | NQO1 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family. (275 aa) |
| | H0VLM6_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (199 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa) |
| | STAT6 | Signal transducer and activator of transcription. (838 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | COA8 | Cytochrome c oxidase assembly factor 8. (193 aa) |
| | CCS | Copper chaperone for superoxide dismutase. (274 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (564 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | AREG | Amphiregulin. (241 aa) |
| | ENSCPOP00000025613 | Proton_antipo_M domain-containing protein. (171 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | ENSCPOP00000024428 | PARP-type domain-containing protein. (104 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | SIRT1 | Sirtuin 1. (717 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (974 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (401 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (214 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
| | IMPACT | Impact RWD domain protein. (318 aa) |
| | STK24 | Serine/threonine kinase 24. (470 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (275 aa) |
| | PRDX3 | Peroxiredoxin 3. (257 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | NET1 | Neuroepithelial cell transforming 1. (597 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | ROMO1 | Reactive oxygen species modulator 1. (79 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | Nudt15 | Nudix hydrolase domain-containing protein. (171 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) |
| | RNF112 | Ring finger protein 112. (654 aa) |
| | MPV17 | Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa) |
| | H0VSI3_CAVPO | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (677 aa) |
| | Parp1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (66 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (664 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | Ercc6l2 | Uncharacterized protein. (1539 aa) |
| | ALDH3A2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | PAX2 | Paired box 2. (393 aa) |
| | SOD2 | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (603 aa) |
| | SOD3 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (246 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) |
| | ARG1 | Arginase. (322 aa) |
| | STK25 | Serine/threonine kinase 25. (426 aa) |
| | MMP2 | Matrix metallopeptidase 2. (662 aa) |
| | TRPC6 | Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (934 aa) |
| | H0WBB7_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (199 aa) |
| | PCGF2 | Polycomb group ring finger 2. (342 aa) |
| | HMOX1 | Heme oxygenase 1. (297 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (797 aa) |
| | LOC106025117 | Nudix hydrolase domain-containing protein. (117 aa) |
| | KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa) |
| | TXNIP | Thioredoxin interacting protein. (392 aa) |
| | ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (176 aa) |
| | TREX1 | Three prime repair exonuclease 1. (314 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1502 aa) |
| | MPO | Myeloperoxidase. (718 aa) |
| | CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (700 aa) |
| | ZNF580 | Zinc finger protein 580. (211 aa) |
| | LOC100719324 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (212 aa) |
| | H0VY83_CAVPO | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (200 aa) |
| | LOC100724477 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (187 aa) |
| | SLC4A1 | Anion exchange protein. (901 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) |
| | BCL2 | BCL2 apoptosis regulator. (183 aa) |
