STRINGSTRING
MSH2 MSH2 MSH6 MSH6 FANCM FANCM HMGB3 HMGB3 GEN1 GEN1 Yy1 Yy1 XRCC3 XRCC3 MEN1 MEN1 BLM BLM WRN WRN RAD51C RAD51C XRCC2 XRCC2 MECP2 MECP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1336 aa)
FANCMFA complementation group M. (1971 aa)
HMGB3High mobility group box 3. (202 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (916 aa)
Yy1Uncharacterized protein. (195 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (338 aa)
MEN1Menin 1. (615 aa)
BLMBLM RecQ like helicase. (1405 aa)
WRNWRN RecQ like helicase. (1462 aa)
RAD51CRAD51 paralog C. (373 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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