STRINGSTRING
TLX2 TLX2 BMPR1A BMPR1A Pou5f1 Pou5f1 COL8A1 COL8A1 FOXC2 FOXC2 MMP2 MMP2 EXOC4 EXOC4 PAX2 PAX2 NOG NOG Inhba Inhba WNT5A WNT5A LEF1 LEF1 ENSCPOP00000024053 ENSCPOP00000024053 HTT HTT NF2 NF2 WNT3A WNT3A SOX7 SOX7 ITGB4 ITGB4 FOXA2 FOXA2 DUSP4 DUSP4 DUSP1 DUSP1 FGFR2 FGFR2 NR4A3 NR4A3 EYA1 EYA1 KIF16B KIF16B BMP7 BMP7 HSBP1 HSBP1 BMPR2 BMPR2 TBX6 TBX6 EPHA2 EPHA2 SMAD3 SMAD3 SFRP2 SFRP2 GRB2 GRB2 ITGB1 ITGB1 Apela Apela TWSG1 TWSG1 CTNNB1 CTNNB1 Prkaca Prkaca TNRC6C TNRC6C SOX17 SOX17 FOXF1 FOXF1 HNF1B HNF1B TBXT TBXT MAP2K1 MAP2K1 MSGN1 MSGN1 VTN VTN ITGA3 ITGA3 EPB41L5 EPB41L5 PRKAR1A PRKAR1A LAMB3 LAMB3 CDC73 CDC73 EOMES EOMES KDM6B KDM6B Gata4 Gata4 ATOH8 ATOH8 BMP4 BMP4 HNF1A HNF1A CHRD CHRD MMP9 MMP9 LAMA3 LAMA3 ITGA5 ITGA5 SETD2 SETD2 GPI GPI ACVR1 ACVR1 H0VDD3_CAVPO H0VDD3_CAVPO CTR9 CTR9 SMAD1 SMAD1 WNT11 WNT11 RTF1 RTF1 POFUT2 POFUT2 WNT3 WNT3 ITGA4 ITGA4 NR0B1 NR0B1 ITGB5 ITGB5 LEO1 LEO1 ITGA8 ITGA8 CRB2 CRB2 ARMC5 ARMC5 ARID1A ARID1A COL4A2 COL4A2 AXIN1 AXIN1 Itgb3 Itgb3 Paf1 Paf1 EXT2 EXT2 TXNRD1 TXNRD1 WLS WLS TBX19 TBX19 TAF10 TAF10 ELF5 ELF5 COL11A1 COL11A1 FN1 FN1 H0VN16_CAVPO H0VN16_CAVPO Etv2 Etv2 SMAD2 SMAD2 MMP8 MMP8 MMP15 MMP15 COL12A1 COL12A1 KDM6A KDM6A ETS2 ETS2 ITGAV ITGAV SIX2 SIX2 ITGA2 ITGA2 NODAL NODAL LHX1 LHX1 HAND1 HAND1 DKK1 DKK1 SRF SRF SCX SCX DUSP2 DUSP2 DUSP5 DUSP5 ECSIT ECSIT SNAI1 SNAI1 MMP14 MMP14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLX2T cell leukemia homeobox 2. (284 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
Pou5f1POU domain protein. (361 aa)
COL8A1Collagen type VIII alpha 1 chain. (744 aa)
FOXC2Forkhead box C2. (441 aa)
MMP2Matrix metallopeptidase 2. (662 aa)
EXOC4Exocyst complex component 4. (975 aa)
PAX2Paired box 2. (393 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (210 aa)
InhbaTGF_BETA_2 domain-containing protein. (133 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
ENSCPOP00000024053Uncharacterized protein. (948 aa)
HTTHuntingtin. (3133 aa)
NF2Neurofibromin 2. (591 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
SOX7SRY-box transcription factor 7. (384 aa)
ITGB4Integrin beta. (1815 aa)
FOXA2Forkhead box A2. (459 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
FGFR2Fibroblast growth factor receptor. (801 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (633 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
KIF16BKinesin family member 16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1267 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HSBP1Heat shock factor binding protein 1. (76 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
TBX6T-box transcription factor 6. (436 aa)
EPHA2EPH receptor A2. (976 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ApelaUncharacterized protein. (54 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
CTNNB1Catenin beta 1. (781 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
TNRC6CTrinucleotide repeat containing adaptor 6C. (1892 aa)
SOX17SRY-box transcription factor 17. (400 aa)
FOXF1Forkhead box F1. (376 aa)
HNF1BHNF1 homeobox B. (558 aa)
TBXTT-box transcription factor T. (435 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
MSGN1Mesogenin 1. (187 aa)
VTNSMB domain-containing protein. (482 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1048 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (705 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
LAMB3Laminin subunit beta 3. (1174 aa)
CDC73Cell division cycle 73. (430 aa)
EOMESEomesodermin. (697 aa)
KDM6BLysine demethylase 6B. (1467 aa)
Gata4Uncharacterized protein. (237 aa)
ATOH8Atonal bHLH transcription factor 8. (320 aa)
BMP4Bone morphogenetic protein 4. (404 aa)
HNF1AHNF1 homeobox A. (628 aa)
CHRDChordin. (892 aa)
MMP9Matrix metallopeptidase 9. (715 aa)
LAMA3Laminin subunit alpha 3. (3262 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1102 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2565 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
H0VDD3_CAVPOHomeobox domain-containing protein. (286 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (732 aa)
POFUT2Protein O-fucosyltransferase 2. (429 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1021 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (383 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (658 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
CRB2Crumbs cell polarity complex component 2. (1242 aa)
ARMC5Armadillo repeat containing 5. (905 aa)
ARID1AAT-rich interaction domain 1A. (1903 aa)
COL4A2Collagen type IV alpha 2 chain. (1479 aa)
AXIN1Axin 1. (863 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (735 aa)
Paf1Uncharacterized protein. (535 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (717 aa)
TXNRD1Thioredoxin reductase 1. (499 aa)
WLSWnt ligand secretion mediator. (541 aa)
TBX19T-box transcription factor 19. (446 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa)
ELF5E74 like ETS transcription factor 5. (255 aa)
COL11A1Collagen type XI alpha 1 chain. (1712 aa)
FN1Fibronectin 1. (2478 aa)
H0VN16_CAVPOUncharacterized protein. (71 aa)
Etv2ETS domain-containing protein. (153 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MMP8Matrix metallopeptidase 8. (468 aa)
MMP15Matrix metallopeptidase 15. (663 aa)
COL12A1Collagen type XII alpha 1 chain. (3066 aa)
KDM6ALysine demethylase 6A. (1164 aa)
ETS2ETS proto-oncogene 2, transcription factor. (447 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (963 aa)
SIX2SIX homeobox 2. (298 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
NODALNodal growth differentiation factor. (351 aa)
LHX1LIM homeobox 1. (406 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (229 aa)
SRFSerum response factor. (461 aa)
SCXScleraxis bHLH transcription factor. (199 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (375 aa)
ECSITECSIT signalling integrator. (431 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MMP14Matrix metallopeptidase 14. (581 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.