STRINGSTRING
ECSIT ECSIT SCX SCX SRF SRF DKK1 DKK1 HAND1 HAND1 NODAL NODAL ITGA2 ITGA2 SIX2 SIX2 KDM6A KDM6A SMAD2 SMAD2 Etv2 Etv2 H0VN16_CAVPO H0VN16_CAVPO TAF10 TAF10 TBX19 TBX19 WLS WLS TXNRD1 TXNRD1 EXT2 EXT2 Itgb3 Itgb3 AXIN1 AXIN1 ARMC5 ARMC5 CRB2 CRB2 ITGA8 ITGA8 WNT3 WNT3 POFUT2 POFUT2 WNT11 WNT11 SMAD1 SMAD1 H0VDD3_CAVPO H0VDD3_CAVPO ACVR1 ACVR1 GPI GPI CHRD CHRD HNF1A HNF1A BMP4 BMP4 KDM6B KDM6B EOMES EOMES PRKAR1A PRKAR1A EPB41L5 EPB41L5 ITGA3 ITGA3 MSGN1 MSGN1 TBXT TBXT FOXF1 FOXF1 Prkaca Prkaca TWSG1 TWSG1 Apela Apela ITGB1 ITGB1 SFRP2 SFRP2 SMAD3 SMAD3 EPHA2 EPHA2 TBX6 TBX6 BMPR2 BMPR2 BMP7 BMP7 EYA1 EYA1 NR4A3 NR4A3 FGFR2 FGFR2 ITGB4 ITGB4 WNT3A WNT3A NF2 NF2 HTT HTT LEF1 LEF1 WNT5A WNT5A Inhba Inhba NOG NOG PAX2 PAX2 EXOC4 EXOC4 FOXC2 FOXC2 Pou5f1 Pou5f1 BMPR1A BMPR1A TLX2 TLX2 SNAI1 SNAI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ECSITECSIT signalling integrator. (431 aa)
SCXScleraxis bHLH transcription factor. (199 aa)
SRFSerum response factor. (461 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (229 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
NODALNodal growth differentiation factor. (351 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
SIX2SIX homeobox 2. (298 aa)
KDM6ALysine demethylase 6A. (1164 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
Etv2ETS domain-containing protein. (153 aa)
H0VN16_CAVPOUncharacterized protein. (71 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa)
TBX19T-box transcription factor 19. (446 aa)
WLSWnt ligand secretion mediator. (541 aa)
TXNRD1Thioredoxin reductase 1. (499 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (717 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (735 aa)
AXIN1Axin 1. (863 aa)
ARMC5Armadillo repeat containing 5. (905 aa)
CRB2Crumbs cell polarity complex component 2. (1242 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
POFUT2Protein O-fucosyltransferase 2. (429 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
H0VDD3_CAVPOHomeobox domain-containing protein. (286 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
CHRDChordin. (892 aa)
HNF1AHNF1 homeobox A. (628 aa)
BMP4Bone morphogenetic protein 4. (404 aa)
KDM6BLysine demethylase 6B. (1467 aa)
EOMESEomesodermin. (697 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (705 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1048 aa)
MSGN1Mesogenin 1. (187 aa)
TBXTT-box transcription factor T. (435 aa)
FOXF1Forkhead box F1. (376 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
ApelaUncharacterized protein. (54 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
EPHA2EPH receptor A2. (976 aa)
TBX6T-box transcription factor 6. (436 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (633 aa)
FGFR2Fibroblast growth factor receptor. (801 aa)
ITGB4Integrin beta. (1815 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
NF2Neurofibromin 2. (591 aa)
HTTHuntingtin. (3133 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
InhbaTGF_BETA_2 domain-containing protein. (133 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (210 aa)
PAX2Paired box 2. (393 aa)
EXOC4Exocyst complex component 4. (975 aa)
FOXC2Forkhead box C2. (441 aa)
Pou5f1POU domain protein. (361 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
TLX2T cell leukemia homeobox 2. (284 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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