12 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	BMP4	Bone morphogenetic protein 4. (404 aa)
	H0VDD3_CAVPO	Homeobox domain-containing protein. (286 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	Etv2	ETS domain-containing protein. (153 aa)
	SIX2	SIX homeobox 2. (298 aa)
	NODAL	Nodal growth differentiation factor. (351 aa)
	Pou5f1	POU domain protein. (361 aa)
	PAX2	Paired box 2. (393 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	TBX6	T-box transcription factor 6. (436 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	NODAL	ENSCPOP00000006206	ENSCPOP00000014277	Bone morphogenetic protein 4.	Nodal growth differentiation factor.	0.609
BMP4	Pou5f1	ENSCPOP00000006206	ENSCPOP00000019114	Bone morphogenetic protein 4.	POU domain protein.	0.481
BMP4	SMAD1	ENSCPOP00000006206	ENSCPOP00000008146	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.797
BMP4	WNT3A	ENSCPOP00000006206	ENSCPOP00000024420	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.578
EYA1	PAX2	ENSCPOP00000028663	ENSCPOP00000021522	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	Paired box 2.	0.618
EYA1	SIX2	ENSCPOP00000028663	ENSCPOP00000014020	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	SIX homeobox 2.	0.874
Etv2	PAX2	ENSCPOP00000011891	ENSCPOP00000021522	ETS domain-containing protein.	Paired box 2.	0.453
H0VDD3_CAVPO	Pou5f1	ENSCPOP00000007983	ENSCPOP00000019114	Homeobox domain-containing protein.	POU domain protein.	0.974
H0VDD3_CAVPO	SMAD1	ENSCPOP00000007983	ENSCPOP00000008146	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.493
H0VDD3_CAVPO	TBX6	ENSCPOP00000007983	ENSCPOP00000030393	Homeobox domain-containing protein.	T-box transcription factor 6.	0.430
NODAL	BMP4	ENSCPOP00000014277	ENSCPOP00000006206	Nodal growth differentiation factor.	Bone morphogenetic protein 4.	0.609
PAX2	EYA1	ENSCPOP00000021522	ENSCPOP00000028663	Paired box 2.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.618
PAX2	Etv2	ENSCPOP00000021522	ENSCPOP00000011891	Paired box 2.	ETS domain-containing protein.	0.453
PAX2	SIX2	ENSCPOP00000021522	ENSCPOP00000014020	Paired box 2.	SIX homeobox 2.	0.512
Pou5f1	BMP4	ENSCPOP00000019114	ENSCPOP00000006206	POU domain protein.	Bone morphogenetic protein 4.	0.481
Pou5f1	H0VDD3_CAVPO	ENSCPOP00000019114	ENSCPOP00000007983	POU domain protein.	Homeobox domain-containing protein.	0.974
Pou5f1	SMAD1	ENSCPOP00000019114	ENSCPOP00000008146	POU domain protein.	Mothers against decapentaplegic homolog.	0.433
SFRP2	WNT3A	ENSCPOP00000031474	ENSCPOP00000024420	Secreted frizzled related protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.906
SIX2	EYA1	ENSCPOP00000014020	ENSCPOP00000028663	SIX homeobox 2.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.874
SIX2	PAX2	ENSCPOP00000014020	ENSCPOP00000021522	SIX homeobox 2.	Paired box 2.	0.512