51 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	BRSK2	BR serine/threonine kinase 2. (718 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	CTNND1	Catenin delta 1. (966 aa)
	FAT1	FAT atypical cadherin 1. (4558 aa)
	ALMS1	ALMS1 centrosome and basal body associated protein. (3698 aa)
	Sh3bp1	Uncharacterized protein. (684 aa)
	CDC42	Cell division cycle 42. (191 aa)
	RAB10	RAB10, member RAS oncogene family. (211 aa)
	MSN	Moesin. (577 aa)
	OPHN1	Uncharacterized protein. (802 aa)
	ACTG1	Actin gamma 1. (375 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
	IFT20	Intraflagellar transport 20. (132 aa)
	DLG3	Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (850 aa)
	SCRIB	Scribble planar cell polarity protein. (1653 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	MYO9A	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2603 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
	ENSCPOP00000025708	SH3 domain-containing protein. (146 aa)
	GRHL3	Grainyhead like transcription factor 3. (603 aa)
	LAMA3	Laminin subunit alpha 3. (3262 aa)
	ZDHHC7	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1864 aa)
	TRAF3IP1	TRAF3 interacting protein 1. (634 aa)
	FUZ	Fuzzy planar cell polarity protein. (392 aa)
	WDR1	WD_REPEATS_REGION domain-containing protein. (600 aa)
	LRRC1	Leucine rich repeat containing 1. (458 aa)
	INTU	Inturned planar cell polarity protein. (938 aa)
	FOXF1	Forkhead box F1. (376 aa)
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	CAMSAP3	Calmodulin regulated spectrin associated protein family member 3. (1210 aa)
	BRSK1	BR serine/threonine kinase 1. (763 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	LAMA5	Laminin subunit alpha 5. (3609 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1263 aa)
	EXOC5	Exocyst complex component 5. (698 aa)
	SYNE4	Spectrin repeat containing nuclear envelope family member 4. (390 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
	CTHRC1	Collagen triple helix repeat containing 1. (247 aa)
	RPGRIP1L	RPGRIP1 like. (1260 aa)
	TCF15	Transcription factor 15. (188 aa)
	LAMA1	Laminin subunit alpha 1. (3018 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2909 aa)
	ASTN2	Astrotactin 2. (1170 aa)
	NPHP1	Nephrocystin 1. (662 aa)
	ACTL8	Actin like 8; Belongs to the actin family. (371 aa)
	H0WDC8_CAVPO	Uncharacterized protein. (420 aa)
	VANGL2	Vang-like protein. (548 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSCPOP00000022236	ENSCPOP00000030661	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Actin gamma 1.	0.909
ACTB	CDC42	ENSCPOP00000022236	ENSCPOP00000031577	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cell division cycle 42.	0.940
ACTB	MSN	ENSCPOP00000022236	ENSCPOP00000031240	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Moesin.	0.922
ACTB	MYO9A	ENSCPOP00000022236	ENSCPOP00000027038	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.630
ACTB	PAFAH1B1	ENSCPOP00000022236	ENSCPOP00000022174	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.535
ACTB	RPGRIP1L	ENSCPOP00000022236	ENSCPOP00000011634	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	RPGRIP1 like.	0.488
ACTB	WDR1	ENSCPOP00000022236	ENSCPOP00000004382	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	WD_REPEATS_REGION domain-containing protein.	0.778
ACTG1	ACTB	ENSCPOP00000030661	ENSCPOP00000022236	Actin gamma 1.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.909
ACTG1	CDC42	ENSCPOP00000030661	ENSCPOP00000031577	Actin gamma 1.	Cell division cycle 42.	0.931
ACTG1	MSN	ENSCPOP00000030661	ENSCPOP00000031240	Actin gamma 1.	Moesin.	0.922
ACTG1	MYO9A	ENSCPOP00000030661	ENSCPOP00000027038	Actin gamma 1.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.630
ACTG1	PAFAH1B1	ENSCPOP00000030661	ENSCPOP00000022174	Actin gamma 1.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.535
ACTG1	RPGRIP1L	ENSCPOP00000030661	ENSCPOP00000011634	Actin gamma 1.	RPGRIP1 like.	0.450
ACTG1	WDR1	ENSCPOP00000030661	ENSCPOP00000004382	Actin gamma 1.	WD_REPEATS_REGION domain-containing protein.	0.778
ACTL8	CDC42	ENSCPOP00000019503	ENSCPOP00000031577	Actin like 8; Belongs to the actin family.	Cell division cycle 42.	0.741
ACTL8	MSN	ENSCPOP00000019503	ENSCPOP00000031240	Actin like 8; Belongs to the actin family.	Moesin.	0.708
ACTL8	MYO9A	ENSCPOP00000019503	ENSCPOP00000027038	Actin like 8; Belongs to the actin family.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.630
ACTL8	PAFAH1B1	ENSCPOP00000019503	ENSCPOP00000022174	Actin like 8; Belongs to the actin family.	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]	0.535
ACTL8	RPGRIP1L	ENSCPOP00000019503	ENSCPOP00000011634	Actin like 8; Belongs to the actin family.	RPGRIP1 like.	0.450
ACTL8	WDR1	ENSCPOP00000019503	ENSCPOP00000004382	Actin like 8; Belongs to the actin family.	WD_REPEATS_REGION domain-containing protein.	0.778