STRINGSTRING
APBB1 APBB1 ROBO3 ROBO3 DCX DCX PTK2 PTK2 H0UVS7_CAVPO H0UVS7_CAVPO ALKBH1 ALKBH1 POMGNT2 POMGNT2 MDGA2 MDGA2 DCC DCC ZMIZ1 ZMIZ1 MARK1 MARK1 NEUROD4 NEUROD4 MATN2 MATN2 EMX2 EMX2 SEMA3A SEMA3A DCDC2 DCDC2 ITGA3 ITGA3 ELP3 ELP3 EOMES EOMES H0V3A7_CAVPO H0V3A7_CAVPO H0V3F2_CAVPO H0V3F2_CAVPO DCLK1 DCLK1 LOC100716676 LOC100716676 CEP85L CEP85L DAB1 DAB1 NEO1 NEO1 SH3RF1 SH3RF1 GFRA3 GFRA3 APBB2 APBB2 COL3A1 COL3A1 CRK CRK CCKAR CCKAR PAX6 PAX6 GAS6 GAS6 CDKL5 CDKL5 NRG1 NRG1 H0VBD1_CAVPO H0VBD1_CAVPO AXL AXL NR4A2 NR4A2 TUBGCP2 TUBGCP2 KIAA0319L KIAA0319L GATA3 GATA3 NRP1 NRP1 DRD2 DRD2 NDNF NDNF GATA2 GATA2 MRTFA MRTFA FZD3 FZD3 SEPTIN14 SEPTIN14 MRTFB MRTFB ADGRL3 ADGRL3 LHX6 LHX6 EVX1 EVX1 PLXNA3 PLXNA3 DNER DNER CNTN2 CNTN2 SEMA3E SEMA3E ASTN1 ASTN1 TNN TNN UNK UNK NDEL1 NDEL1 Mapt Mapt FEZF1 FEZF1 DISC1 DISC1 MET MET CELSR1 CELSR1 Kiaa0319 Kiaa0319 TBX20 TBX20 ASTN2 ASTN2 SDCCAG8 SDCCAG8 LHX1 LHX1 AUTS2 AUTS2 PHOX2B PHOX2B ARX ARX NKX2-1 NKX2-1 SRF SRF CDK5R1 CDK5R1 SPOCK1 SPOCK1 Mnx1 Mnx1 NKX6-2 NKX6-2 BARHL2 BARHL2 Aspm Aspm ESR2 ESR2 OLIG3 OLIG3 NDE1 NDE1 LOC100725331 LOC100725331 LRP12 LRP12 PEX5 PEX5 BARHL1 BARHL1 CTNNB1 CTNNB1 FBXO45 FBXO45 PEX13 PEX13 CELSR2 CELSR2 NAV1 NAV1 CDK5 CDK5 PCM1 PCM1 FGF13 FGF13 MDGA1 MDGA1 BAX BAX Rapgef2 Rapgef2 RELN RELN Cdk5r2 Cdk5r2 TOP2B TOP2B USP9X USP9X Ywhae Ywhae KIRREL3 KIRREL3 FEZF2 FEZF2 SEMA6A SEMA6A CELSR3 CELSR3 GPM6A GPM6A CRKL CRKL TRIM46 TRIM46 Ccr4 Ccr4 KATNA1 KATNA1 CXCR4 CXCR4 DDIT4 DDIT4 Vegfa Vegfa MYH10 MYH10 Septin4 Septin4 PRKG1 PRKG1 PEX7 PEX7 FYN FYN DRD1 DRD1 PSEN1 PSEN1 NRP2 NRP2 MAPK8 MAPK8 NTRK3 NTRK3 DNAAF4 DNAAF4 Pitx2 Pitx2 PEX2 PEX2 CXCL12 CXCL12 RAC1 RAC1 MEF2C MEF2C PAFAH1B1 PAFAH1B1 CCK CCK ACAP3 ACAP3 NTRK2 NTRK2 H0WD89_CAVPO H0WD89_CAVPO Bbs1 Bbs1 PCNT PCNT ASCL1 ASCL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APBB1Amyloid beta precursor protein binding family B member 1. (709 aa)
ROBO3Roundabout guidance receptor 3. (1394 aa)
DCXDoublecortin. (366 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
H0UVS7_CAVPOUncharacterized protein. (1296 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
POMGNT2Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-). (580 aa)
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2. (944 aa)
DCCDCC netrin 1 receptor. (991 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1068 aa)
MARK1Non-specific serine/threonine protein kinase. (795 aa)
NEUROD4Neurogenic differentiation factor. (331 aa)
MATN2Matrilin 2. (921 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
DCDC2Doublecortin domain containing 2. (469 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1048 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (561 aa)
EOMESEomesodermin. (697 aa)
H0V3A7_CAVPOUncharacterized protein. (1320 aa)
H0V3F2_CAVPOUncharacterized protein. (1365 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
LOC100716676TPR_REGION domain-containing protein. (567 aa)
CEP85LCentrosomal protein 85 like. (792 aa)
DAB1DAB adaptor protein 1. (555 aa)
NEO1Neogenin 1. (1465 aa)
SH3RF1SH3 domain containing ring finger 1. (889 aa)
GFRA3GDNF family receptor alpha 3. (407 aa)
APBB2Amyloid beta precursor protein binding family B member 2. (761 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
CRKCRK proto-oncogene, adaptor protein. (281 aa)
CCKARCholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (430 aa)
PAX6Paired box 6. (436 aa)
GAS6Growth arrest specific 6. (678 aa)
CDKL5Cyclin dependent kinase like 5. (947 aa)
NRG1Neuregulin 1. (700 aa)
H0VBD1_CAVPO14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (105 aa)
AXLAXL receptor tyrosine kinase. (888 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (896 aa)
KIAA0319LKIAA0319 like. (1069 aa)
GATA3GATA binding protein 3. (443 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (925 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
GATA2GATA binding protein 2. (374 aa)
MRTFAMyocardin related transcription factor A. (791 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (346 aa)
MRTFBMyocardin related transcription factor B. (1094 aa)
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1392 aa)
LHX6LIM homeobox 6. (364 aa)
EVX1Even-skipped homeobox 1. (395 aa)
PLXNA3Plexin A3. (1872 aa)
DNERDelta/notch like EGF repeat containing. (741 aa)
CNTN2Contactin 2. (1041 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (648 aa)
ASTN1Astrotactin 1. (1216 aa)
TNNTenascin N. (1473 aa)
UNKUnk zinc finger. (810 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
MaptMicrotubule-associated protein. (370 aa)
FEZF1FEZ family zinc finger 1. (472 aa)
DISC1DISC1 scaffold protein. (775 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2909 aa)
Kiaa0319Uncharacterized protein. (483 aa)
TBX20T-box transcription factor 20. (446 aa)
ASTN2Astrotactin 2. (1170 aa)
SDCCAG8Serologically defined colon cancer antigen 8. (714 aa)
LHX1LIM homeobox 1. (406 aa)
AUTS2Activator of transcription and developmental regulator AUTS2. (1014 aa)
PHOX2BPaired like homeobox 2B. (284 aa)
ARXAristaless related homeobox. (418 aa)
NKX2-1Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis (By similarity). (344 aa)
SRFSerum response factor. (461 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
SPOCK1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (379 aa)
Mnx1Homeobox domain-containing protein. (233 aa)
NKX6-2NK6 homeobox 2. (267 aa)
BARHL2BarH like homeobox 2. (383 aa)
AspmUncharacterized protein. (1053 aa)
ESR2Estrogen receptor 2. (568 aa)
OLIG3Oligodendrocyte transcription factor 3. (273 aa)
NDE1NudE neurodevelopment protein 1. (350 aa)
LOC100725331Uncharacterized protein. (1433 aa)
LRP12LDL receptor related protein 12. (773 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
BARHL1BarH like homeobox 1. (327 aa)
CTNNB1Catenin beta 1. (781 aa)
FBXO45F-box protein 45. (283 aa)
PEX13Peroxisomal biogenesis factor 13. (402 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2925 aa)
NAV1Neuron navigator 1. (2146 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
PCM1Pericentriolar material 1. (2080 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (962 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
Rapgef2Uncharacterized protein. (1640 aa)
RELNReelin. (3423 aa)
Cdk5r2Uncharacterized protein. (97 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1614 aa)
USP9XUbiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2558 aa)
Ywhae14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (777 aa)
FEZF2FEZ family zinc finger 2. (461 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3301 aa)
GPM6AGlycoprotein M6A. (278 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
TRIM46Tripartite motif containing 46. (672 aa)
Ccr4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (492 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa)
DDIT4DNA damage inducible transcript 4. (228 aa)
VegfaVascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By s [...] (186 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
Septin4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
FYNTyrosine-protein kinase. (537 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
DNAAF4Dynein axonemal assembly factor 4. (421 aa)
Pitx2Homeobox protein. (325 aa)
PEX2Peroxisomal biogenesis factor 2. (304 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CCKCholecystokinin. (115 aa)
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (833 aa)
NTRK2Tyrosine-protein kinase receptor. (816 aa)
H0WD89_CAVPOUncharacterized protein. (117 aa)
Bbs1BBS1 domain-containing protein. (593 aa)
PCNTPericentrin. (2941 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (215 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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