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| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (501 aa) |
| | HNF1A | HNF1 homeobox A. (628 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (851 aa) |
| | CCDC40 | Coiled-coil domain containing 40. (1120 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (419 aa) |
| | Aurka | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (384 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (477 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | PIK3CA | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family. (1044 aa) |
| | HMBS | Hydroxymethylbilane synthase. (361 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | ADA | Adenosine deaminase. (365 aa) |
| | NF1 | Neurofibromin 1. (2750 aa) |
| | Csnk2a1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (765 aa) |
| | Ahr | Uncharacterized protein. (832 aa) |
| | GLI1 | GLI family zinc finger 1. (1104 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1499 aa) |
| | TBX3 | T-box transcription factor 3. (739 aa) |
| | UPB1 | Beta-ureidopropionase 1. (384 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (747 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4283 aa) |
| | VTN | SMB domain-containing protein. (482 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | SP3 | Sp3 transcription factor. (690 aa) |
| | SEC63 | SEC63 homolog, protein translocation regulator. (742 aa) |
| | PTCH1 | Patched 1. (1379 aa) |
| | ZIC3 | Zic family member 3. (246 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (131 aa) |
| | HNF1B | HNF1 homeobox B. (558 aa) |
| | FGL1 | Fibrinogen like 1. (219 aa) |
| | CPB2 | Carboxypeptidase B2. (423 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1214 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa) |
| | UGT1A6 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa) |
| | Ggt1 | Uncharacterized protein. (569 aa) |
| | Atf7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (411 aa) |
| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | ENSCPOP00000025446 | Uncharacterized protein. (281 aa) |
| | SRSF5 | Serine and arginine rich splicing factor 5. (274 aa) |
| | GAK | Cyclin G associated kinase. (1310 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (872 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (699 aa) |
| | Hhex | Homeobox domain-containing protein. (98 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | ICMT | Protein-S-isoprenylcysteine O-methyltransferase. (284 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | LOC100722203 | BZIP domain-containing protein. (150 aa) |
| | MPST | Sulfurtransferase. (297 aa) |
| | RHBDD3 | Rhomboid domain containing 3. (386 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (409 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2738 aa) |
| | CADM1 | Cell adhesion molecule 1. (475 aa) |
| | TET2 | Tet methylcytosine dioxygenase 2. (1863 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa) |
| | RARA | Retinoic acid receptor alpha. (462 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (313 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (376 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (1253 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) |
| | PTCD2 | Pentatricopeptide repeat domain 2. (383 aa) |
| | ACO2 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa) |
| | EPHX1 | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (455 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | SOD2 | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | LSR | Lipolysis stimulated lipoprotein receptor. (586 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (253 aa) |
| | ARG1 | Arginase. (322 aa) |
| | HLX | H2.0 like homeobox. (442 aa) |
| | ASS1 | Argininosuccinate synthase 1. (415 aa) |
| | HMOX1 | Heme oxygenase 1. (297 aa) |
| | Asl | Uncharacterized protein. (465 aa) |
| | LOC100718030 | Solute carrier organic anion transporter family member. (682 aa) |
| | ATP7A | ATPase copper transporting alpha. (1433 aa) |
| | CEBPB | CCAAT enhancer binding protein beta. (216 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1431 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (549 aa) |
| | Cebpa | Uncharacterized protein. (158 aa) |
| | Baat | Bile_Hydr_Trans domain-containing protein. (47 aa) |
| | PRKCSH | Protein kinase C substrate 80K-H. (532 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | H0VW22_CAVPO | Protein kinase domain-containing protein. (399 aa) |
| | CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2033 aa) |
| | FPGS | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (582 aa) |
| | NODAL | Nodal growth differentiation factor. (351 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa) |
| | NOTCH2 | Notch receptor 2. (2455 aa) |
| | Nphp3 | TPR_REGION domain-containing protein. (1281 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (686 aa) |
| | TYMS | Thymidylate synthetase. (314 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1636 aa) |
| | FOXM1 | Forkhead box M1. (762 aa) |
| | CCDC39 | Coiled-coil domain containing 39. (678 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (839 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | SERPINA10 | Serpin family A member 10; Belongs to the serpin family. (442 aa) |
| | RGN | Regucalcin. (299 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1380 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1247 aa) |
| | IGF2R | Insulin like growth factor 2 receptor. (2473 aa) |
| | C6orf58 | Chromosome 6 open reading frame 58. (336 aa) |
| | RPGRIP1L | RPGRIP1 like. (1260 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) |
| | PROC | Protein C, inactivator of coagulation factors Va and VIIIa. (464 aa) |
| | EZH1 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | GFER | Sulfhydryl oxidase. (200 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | LOC100718313 | Solute carrier organic anion transporter family member. (608 aa) |
| | ACADM | Acyl-CoA dehydrogenase medium chain. (363 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (783 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (652 aa) |
| | DNAAF1 | Dynein assembly factor 1, axonemal. (606 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | MRTFB | Myocardin related transcription factor B. (1094 aa) |
| | PTPN3 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (912 aa) |
| | TGFA | Transforming growth factor alpha. (159 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | IFT88 | Intraflagellar transport 88. (825 aa) |
| | ELK1 | ETS transcription factor ELK1. (422 aa) |
| | PKM | Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa) |
| | UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1252 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | XBP1 | X-box binding protein 1. (268 aa) |
| | LOC100718591 | Solute carrier organic anion transporter family member. (658 aa) |
| | AACS | Acetoacetyl-CoA synthetase. (672 aa) |
| | MAN2A1 | Alpha-mannosidase. (1122 aa) |
| | E2F7 | E2F transcription factor 7. (904 aa) |
| | E2F8 | E2F transcription factor 8. (860 aa) |
