STRINGSTRING
PLA2G4A PLA2G4A KISS1 KISS1 GJB2 GJB2 VDR VDR BMPR2 BMPR2 STC1 STC1 PTGIS PTGIS LIF LIF AKT1 AKT1 STOX2 STOX2 DAZAP1 DAZAP1 MAPK3 MAPK3 TCF23 TCF23 DEDD DEDD NDP NDP PRDX3 PRDX3 RXRB RXRB LDOC1 LDOC1 GHRL GHRL H0W794_CAVPO H0W794_CAVPO BSG BSG CYP27B1 CYP27B1 H0W0Z6_CAVPO H0W0Z6_CAVPO JUNB JUNB NODAL NODAL PRDM1 PRDM1 GHSR GHSR RXRA RXRA MEN1 MEN1 PTGS2 PTGS2 CITED2 CITED2 TMED2 TMED2 ASH1L ASH1L EPOR EPOR PTN PTN CTSB CTSB CTSV CTSV TPPP3 TPPP3 PPARD PPARD CDH1 CDH1 MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4APhospholipase A2. (749 aa)
KISS1KiSS-1 metastasis suppressor. (128 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
VDRVitamin D receptor. (424 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
STC1Stanniocalcin 1. (247 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (475 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
STOX2Storkhead box 2. (890 aa)
DAZAP1DAZ associated protein 1. (400 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
TCF23Transcription factor 23. (210 aa)
DEDDDeath effector domain containing. (318 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
PRDX3Peroxiredoxin 3. (257 aa)
RXRBRetinoid X receptor beta. (414 aa)
LDOC1LDOC1 regulator of NFKB signaling. (145 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
H0W794_CAVPODUF4939 domain-containing protein. (110 aa)
BSGBasigin (Ok blood group). (384 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa)
H0W0Z6_CAVPODUF4939 domain-containing protein. (113 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
NODALNodal growth differentiation factor. (351 aa)
PRDM1PR/SET domain 1. (813 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (302 aa)
RXRARetinoid X receptor alpha. (459 aa)
MEN1Menin 1. (615 aa)
PTGS2Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
ASH1LASH1 like histone lysine methyltransferase. (2942 aa)
EPORErythropoietin receptor. (540 aa)
PTNPleiotrophin. (168 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (340 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (333 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa)
MAPK1Mitogen-activated protein kinase. (325 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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