13 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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gene fusions

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protein homology

Your Input:
	HMGA1	High mobility group AT-hook 1. (108 aa)
	ALKBH1	AlkB homolog 1, histone H2A dioxygenase. (389 aa)
	NTHL1	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (260 aa)
	NEIL3	Nei like DNA glycosylase 3. (607 aa)
	APLF	Aprataxin and PNKP like factor. (498 aa)
	NEIL2	Nei like DNA glycosylase 2. (336 aa)
	APEX2	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa)
	OGG1	8-oxoguanine DNA glycosylase. (303 aa)
	NEIL1	Nei like DNA glycosylase 1. (401 aa)
	H0VN16_CAVPO	Uncharacterized protein. (71 aa)
	Rps3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	ENSCPOP00000029431	Uncharacterized protein. (111 aa)
	APEX1	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALKBH1	OGG1	ENSCPOP00000001354	ENSCPOP00000007880	AlkB homolog 1, histone H2A dioxygenase.	8-oxoguanine DNA glycosylase.	0.406
APEX1	APEX2	ENSCPOP00000032125	ENSCPOP00000006545	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.927
APEX1	NEIL1	ENSCPOP00000032125	ENSCPOP00000009702	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nei like DNA glycosylase 1.	0.410
APEX1	NEIL3	ENSCPOP00000032125	ENSCPOP00000002978	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nei like DNA glycosylase 3.	0.525
APEX1	NTHL1	ENSCPOP00000032125	ENSCPOP00000002908	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.996
APEX1	OGG1	ENSCPOP00000032125	ENSCPOP00000007880	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.902
APEX2	APEX1	ENSCPOP00000006545	ENSCPOP00000032125	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.927
APEX2	NEIL3	ENSCPOP00000006545	ENSCPOP00000002978	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nei like DNA glycosylase 3.	0.525
APEX2	NTHL1	ENSCPOP00000006545	ENSCPOP00000002908	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.927
APEX2	OGG1	ENSCPOP00000006545	ENSCPOP00000007880	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	8-oxoguanine DNA glycosylase.	0.885
H0VN16_CAVPO	HMGA1	ENSCPOP00000011822	ENSCPOP00000031584	Uncharacterized protein.	High mobility group AT-hook 1.	0.696
HMGA1	H0VN16_CAVPO	ENSCPOP00000031584	ENSCPOP00000011822	High mobility group AT-hook 1.	Uncharacterized protein.	0.696
NEIL1	APEX1	ENSCPOP00000009702	ENSCPOP00000032125	Nei like DNA glycosylase 1.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.410
NEIL1	NEIL2	ENSCPOP00000009702	ENSCPOP00000005469	Nei like DNA glycosylase 1.	Nei like DNA glycosylase 2.	0.876
NEIL1	NEIL3	ENSCPOP00000009702	ENSCPOP00000002978	Nei like DNA glycosylase 1.	Nei like DNA glycosylase 3.	0.590
NEIL1	NTHL1	ENSCPOP00000009702	ENSCPOP00000002908	Nei like DNA glycosylase 1.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.587
NEIL1	OGG1	ENSCPOP00000009702	ENSCPOP00000007880	Nei like DNA glycosylase 1.	8-oxoguanine DNA glycosylase.	0.831
NEIL2	NEIL1	ENSCPOP00000005469	ENSCPOP00000009702	Nei like DNA glycosylase 2.	Nei like DNA glycosylase 1.	0.876
NEIL2	NTHL1	ENSCPOP00000005469	ENSCPOP00000002908	Nei like DNA glycosylase 2.	Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.	0.584
NEIL2	OGG1	ENSCPOP00000005469	ENSCPOP00000007880	Nei like DNA glycosylase 2.	8-oxoguanine DNA glycosylase.	0.762