55 items (Cavia porcellus) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	NME1	Nucleoside diphosphate kinase. (152 aa)
	ENDOV	Endonuclease V. (260 aa)
	DNASE1L1	Deoxyribonuclease; Belongs to the DNase I family. (307 aa)
	Ankle1	Uncharacterized protein. (520 aa)
	APEX2	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa)
	RBBP8	RB binding protein 8, endonuclease. (900 aa)
	MUS81	MUS81 structure-specific endonuclease subunit. (562 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (794 aa)
	PLD3	Phospholipase D family member 3. (490 aa)
	EXD2	Exonuclease 3'-5' domain containing 2. (619 aa)
	H0VGS2_CAVPO	Uncharacterized protein. (611 aa)
	REXO2	RNA exonuclease 2. (237 aa)
	DNASE2B	Deoxyribonuclease 2 beta. (361 aa)
	FAN1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (987 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa)
	DCLRE1A	DNA cross-link repair 1A. (913 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (706 aa)
	TREX1	Three prime repair exonuclease 1. (314 aa)
	TREX2	Three prime repair exonuclease 2. (236 aa)
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (338 aa)
	RAD9B	Cell cycle checkpoint control protein; Belongs to the rad9 family. (401 aa)
	ENDOG	Endonuclease. (299 aa)
	Slx1a	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (266 aa)
	LOC100736130	Uncharacterized protein. (287 aa)
	PTBP1	Polypyrimidine tract binding protein 1. (557 aa)
	TATDN1	TatD DNase domain containing 1. (297 aa)
	ISG20	Interferon stimulated exonuclease gene 20. (190 aa)
	Bivm	Uncharacterized protein. (503 aa)
	DNA2	DNA replication helicase/nuclease 2. (1021 aa)
	GEN1	GEN1 Holliday junction 5' flap endonuclease. (916 aa)
	Dclre1b	Lactamase_B domain-containing protein. (190 aa)
	EXO5	Exonuclease 5. (373 aa)
	ENSCPOP00000025543	AAA_12 domain-containing protein. (243 aa)
	DNASE1L3	Deoxyribonuclease; Belongs to the DNase I family. (302 aa)
	DNASE1L2	Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
	Rps3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	EXOG	Exo/endonuclease G. (358 aa)
	APTX	Aprataxin. (341 aa)
	ENSCPOP00000029431	Uncharacterized protein. (111 aa)
	MGME1	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (356 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (300 aa)
	APEX1	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
	DFFB	DNA fragmentation factor subunit beta. (302 aa)
	EXO1	Exonuclease 1. (839 aa)
	DNASE2	Deoxyribonuclease 2, lysosomal. (357 aa)
	ERCC5	ERCC excision repair 5, endonuclease. (1059 aa)
	MEIOB	Meiosis specific with OB-fold. (471 aa)
	PLD4	Phospholipase D family member 4. (501 aa)
	Rad50	Zinc-hook domain-containing protein. (1275 aa)
	DCLRE1C	DNA cross-link repair 1C. (688 aa)
	APLF	Aprataxin and PNKP like factor. (498 aa)
	DICER1	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1903 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
	RAD51C	RAD51 paralog C. (373 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	APEX2	ENSCPOP00000032125	ENSCPOP00000006545	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.927
APEX1	APTX	ENSCPOP00000032125	ENSCPOP00000029271	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Aprataxin.	0.632
APEX1	Bivm	ENSCPOP00000032125	ENSCPOP00000022724	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uncharacterized protein.	0.719
APEX1	ERCC1	ENSCPOP00000032125	ENSCPOP00000031152	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.612
APEX1	ERCC4	ENSCPOP00000032125	ENSCPOP00000004055	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	ERCC excision repair 4, endonuclease catalytic subunit.	0.825
APEX1	ERCC5	ENSCPOP00000032125	ENSCPOP00000001242	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	ERCC excision repair 5, endonuclease.	0.719
APEX1	EXO1	ENSCPOP00000032125	ENSCPOP00000000318	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Exonuclease 1.	0.793
APEX1	FEN1	ENSCPOP00000032125	ENSCPOP00000032223	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.994
APEX1	GEN1	ENSCPOP00000032125	ENSCPOP00000023506	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	GEN1 Holliday junction 5' flap endonuclease.	0.719
APEX1	MEIOB	ENSCPOP00000032125	ENSCPOP00000001396	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Meiosis specific with OB-fold.	0.590
APEX1	MRE11	ENSCPOP00000032125	ENSCPOP00000013122	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.490
APEX1	MUS81	ENSCPOP00000032125	ENSCPOP00000007258	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	MUS81 structure-specific endonuclease subunit.	0.701
APEX1	NME1	ENSCPOP00000032125	ENSCPOP00000004832	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Nucleoside diphosphate kinase.	0.592
APEX1	POLE	ENSCPOP00000032125	ENSCPOP00000012269	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.788
APEX1	XRCC3	ENSCPOP00000032125	ENSCPOP00000015766	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.511
APEX2	APEX1	ENSCPOP00000006545	ENSCPOP00000032125	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.927
APEX2	APTX	ENSCPOP00000006545	ENSCPOP00000029271	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Aprataxin.	0.487
APEX2	Bivm	ENSCPOP00000006545	ENSCPOP00000022724	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uncharacterized protein.	0.719
APEX2	ERCC1	ENSCPOP00000006545	ENSCPOP00000031152	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.610
APEX2	ERCC4	ENSCPOP00000006545	ENSCPOP00000004055	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	ERCC excision repair 4, endonuclease catalytic subunit.	0.825