STRINGSTRING
Kcnk6 Kcnk6 KCNQ5 KCNQ5 KCNN2 KCNN2 KCNB2 KCNB2 CLCN3 CLCN3 KCNK1 KCNK1 GRIN2C GRIN2C KCNH6 KCNH6 KCND3 KCND3 KCNA10 KCNA10 KCNH5 KCNH5 KCNAB3 KCNAB3 KCNK10 KCNK10 CACNG2 CACNG2 KCNT2 KCNT2 TPCN2 TPCN2 SCN1A SCN1A SCN2A SCN2A TMC1 TMC1 SNAP25 SNAP25 KCNAB2 KCNAB2 KCNH1 KCNH1 CACNB3 CACNB3 KCNC2 KCNC2 KCNK18 KCNK18 SCN4B SCN4B CACNA1B CACNA1B KCNA1 KCNA1 KCNAB1 KCNAB1 KCNQ4 KCNQ4 H0V4J9_CAVPO H0V4J9_CAVPO CACNA2D4 CACNA2D4 TPCN1 TPCN1 KCNV1 KCNV1 Cacnb2 Cacnb2 GRIN2B GRIN2B GRIN3A GRIN3A CLIC2 CLIC2 H0VC92_CAVPO H0VC92_CAVPO SCN4A SCN4A ERC1 ERC1 KCNQ3 KCNQ3 CLCN2 CLCN2 CACNA2D3 CACNA2D3 SCN3A SCN3A CLCN5 CLCN5 KCNJ6 KCNJ6 VDAC3 VDAC3 CALHM1 CALHM1 KCNH3 KCNH3 KCNC1 KCNC1 Trpa1 Trpa1 KCNJ8 KCNJ8 CNGA2 CNGA2 CACHD1 CACHD1 KCND2 KCND2 CACNA1I CACNA1I CACNA1H CACNA1H KCNG3 KCNG3 CATSPER3 CATSPER3 KCNC4 KCNC4 SCN9A SCN9A CALHM3 CALHM3 GRIN2A GRIN2A Kcnk7 Kcnk7 SCN10A SCN10A Kcnj13 Kcnj13 HCN1 HCN1 SCN7A SCN7A KCNIP1 KCNIP1 PKD2 PKD2 CLCN1 CLCN1 CACNA1E CACNA1E KCNIP3 KCNIP3 CACNG7 CACNG7 TMC2 TMC2 LRRC52 LRRC52 ITGAV ITGAV P2rx5 P2rx5 SCN8A SCN8A RYR1 RYR1 KCNN3 KCNN3 KCNA3 KCNA3 KCNQ1 KCNQ1 Kcnj12 Kcnj12 KCNK3 KCNK3 H0VXJ2_CAVPO H0VXJ2_CAVPO KCNS3 KCNS3 OPRM1 OPRM1 KCNJ14 KCNJ14 KCNJ4 KCNJ4 KCNH2 KCNH2 GRM7 GRM7 CACNG4 CACNG4 KCNT1 KCNT1 KCNK9 KCNK9 KCNS2 KCNS2 CACNA1F CACNA1F KCNC3 KCNC3 KCNF1 KCNF1 H0W649_CAVPO H0W649_CAVPO KCNJ1 KCNJ1 HVCN1 HVCN1 KCNN1 KCNN1 CACNA2D2 CACNA2D2 CLIC1 CLIC1 KCNK5 KCNK5 HCN3 HCN3 KCNA5 KCNA5 KCNK4 KCNK4 CACNA1A CACNA1A KCNH4 KCNH4 KCNJ11 KCNJ11 CNR1 CNR1 CACNA1G CACNA1G KCNJ9 KCNJ9 HCN4 HCN4 KCNH7 KCNH7 SCN1B SCN1B HCN2 HCN2 CACNA1S CACNA1S KCNIP2 KCNIP2 CACNA2D1 CACNA2D1 CACNG6 CACNG6 SCN11A SCN11A KCNJ15 KCNJ15 KCNE2 KCNE2 KCNK13 KCNK13 KCNA6 KCNA6 KCNS1 KCNS1 KCNE3 KCNE3 KCNG1 KCNG1 Vdac1 Vdac1 MARCKSL1 MARCKSL1 Kcng2 Kcng2 KCNIP4 KCNIP4 CLIC5 CLIC5 ANO6 ANO6 KCNA2 KCNA2 KCNK12 KCNK12 Kcnj3 Kcnj3 KCNA7 KCNA7 KCNK2 KCNK2 CDK5 CDK5 SCN5A SCN5A ANO1 ANO1 KCNA4 KCNA4 KCNMA1 KCNMA1 CACNA1D CACNA1D Ncs1 Ncs1 KCND1 KCND1 LYSMD4 LYSMD4 Kcnj2 Kcnj2 KCNE4 KCNE4 ENSCPOP00000030667 ENSCPOP00000030667 KCNJ16 KCNJ16 LRRC55 LRRC55 CLCN4 CLCN4 GRIN2D GRIN2D LYSMD3 LYSMD3 CLCN6 CLCN6 NALCN NALCN KCNJ5 KCNJ5 TMEM37 TMEM37 GRIN1 GRIN1 KCNJ10 KCNJ10 CLCN7 CLCN7 KCNG4 KCNG4 SCN2B SCN2B Cacnb4 Cacnb4 VDAC2 VDAC2 KCNQ2 KCNQ2 TSPOAP1 TSPOAP1 SCN3B SCN3B LOC100714922 LOC100714922 LRRC38 LRRC38 TMEM109 TMEM109 KCNH8 KCNH8 CLIC4 CLIC4 KCNE1 KCNE1 ENSCPOP00000023749 ENSCPOP00000023749 CACNG3 CACNG3 LOC100730738 LOC100730738 ENSCPOP00000023326 ENSCPOP00000023326 KCNK16 KCNK16 CACNG1 CACNG1 CACNB1 CACNB1 CACNA1C CACNA1C ENSCPOP00000029147 ENSCPOP00000029147 KCNV2 KCNV2 KCNB1 KCNB1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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Kcnk6Potassium channel subfamily K member. (312 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (908 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (842 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
CLCN3H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily. (865 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1209 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (916 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (989 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (535 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
KCNT2Potassium sodium-activated channel subfamily T member 2. (1010 aa)
TPCN2Two pore channel 2. (752 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
TMC1Transmembrane channel-like protein. (761 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (205 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
KCNH1Uncharacterized protein. (989 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (384 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (184 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
H0V4J9_CAVPOUncharacterized protein. (291 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1101 aa)
TPCN1Two pore channel 1. (817 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
Cacnb2SH3 domain-containing protein. (621 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1381 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1114 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
H0VC92_CAVPOUncharacterized protein. (384 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1829 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1116 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
CLCN2Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport (By similarity). Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity); Belongs [...] (889 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (991 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa)
CLCN5H(+)/Cl(-) exchange transporter 5; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 5/CLCN5 subfamily. (787 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (429 aa)
VDAC3Voltage dependent anion channel 3. (283 aa)
CALHM1Calcium homeostasis modulator 1. (344 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1085 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
Trpa1ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (991 aa)
KCNJ8Uncharacterized protein. (468 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (663 aa)
CACHD1Cache domain containing 1. (1272 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2067 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa)
CATSPER3Cation channel sperm associated 3. (380 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa)
CALHM3Calcium homeostasis modulator 3. (347 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1462 aa)
Kcnk7Potassium channel subfamily K member. (315 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
Kcnj13Inward rectifier potassium channel 13; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependen [...] (352 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (671 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1520 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (839 aa)
CLCN1Chloride channel protein. (990 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
TMC2Transmembrane channel-like protein. (868 aa)
LRRC52Leucine rich repeat containing 52. (316 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (963 aa)
P2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (456 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1876 aa)
RYR1Ryanodine receptor 1. (4554 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (720 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (528 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
Kcnj12Uncharacterized protein. (535 aa)
KCNK3Potassium two pore domain channel subfamily K member 3. (270 aa)
H0VXJ2_CAVPOUncharacterized protein. (240 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
OPRM1Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP- bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell ty [...] (416 aa)
KCNJ14Inwardly-rectifying potassium channel Kir2.4. (439 aa)
KCNJ4Uncharacterized protein. (443 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
GRM7Glutamate metabotropic receptor 7. (922 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (325 aa)
KCNT1Potassium sodium-activated channel subfamily T member 1. (1229 aa)
KCNK9Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (365 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (445 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1774 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (435 aa)
H0W649_CAVPOVoltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (280 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (376 aa)
HVCN1Hydrogen voltage gated channel 1. (283 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (558 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1129 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (458 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (977 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smo [...] (390 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2372 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (392 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1186 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1173 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (216 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (783 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1078 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (257 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1719 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity). (421 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (405 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (491 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (497 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (105 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (515 aa)
Vdac1Uncharacterized protein. (283 aa)
MARCKSL1MARCKS like 1. (238 aa)
Kcng2Ion_trans domain-containing protein; Belongs to the potassium channel family. (235 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (143 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
ANO6Anoctamin. (922 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
KCNK12Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (424 aa)
Kcnj3IRK_C domain-containing protein. (194 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (469 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa)
ANO1Anoctamin. (1011 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2164 aa)
Ncs1Uncharacterized protein. (168 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
LYSMD4LysM domain containing 4. (298 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (174 aa)
ENSCPOP00000030667Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (245 aa)
KCNJ16Inwardly-rectifying potassium channel Kir5.1. (419 aa)
LRRC55Leucine rich repeat containing 55. (328 aa)
CLCN4Chloride channel protein. (747 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (808 aa)
LYSMD3LysM domain containing 3. (305 aa)
CLCN6Chloride channel protein. (899 aa)
NALCNSodium leak channel, non-selective. (1738 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
TMEM37Transmembrane protein 37. (197 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (943 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
CLCN7Chloride channel protein. (804 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (509 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (209 aa)
Cacnb4SH3 domain-containing protein. (519 aa)
VDAC2Voltage dependent anion channel 2. (294 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
TSPOAP1TSPO associated protein 1. (1837 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
LOC100714922Ion_trans domain-containing protein. (685 aa)
LRRC38Leucine rich repeat containing 38. (295 aa)
TMEM109Transmembrane protein 109. (243 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
ENSCPOP00000023749Uncharacterized protein. (244 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
LOC100730738Chloride channel protein. (729 aa)
ENSCPOP00000023326Uncharacterized protein. (373 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (300 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (641 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2089 aa)
ENSCPOP00000029147Uncharacterized protein. (272 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (558 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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