STRINGSTRING
GLRA2 GLRA2 SLC26A9 SLC26A9 GABRA4 GABRA4 PACC1 PACC1 CLCN2 CLCN2 SLC17A8 SLC17A8 SLC1A4 SLC1A4 CLIC2 CLIC2 ANO8 ANO8 GABRA1 GABRA1 SLC17A7 SLC17A7 BEST1 BEST1 GABRB3 GABRB3 ANO3 ANO3 GABRA5 GABRA5 ANO9 ANO9 SLC26A7 SLC26A7 GABRD GABRD GABRG2 GABRG2 GABRA3 GABRA3 LOC100727546 LOC100727546 CLCC1 CLCC1 ANO2 ANO2 CLCN3 CLCN3 BEST2 BEST2 GABRP GABRP BEST3 BEST3 ANO4 ANO4 ENSCPOP00000030667 ENSCPOP00000030667 GLRB GLRB CLCN4 CLCN4 CLIC5 CLIC5 Ttyh3 Ttyh3 ANO6 ANO6 ANO1 ANO1 TTYH1 TTYH1 CLCN6 CLCN6 CLCN7 CLCN7 ENSCPOP00000025593 ENSCPOP00000025593 CLIC3 CLIC3 CLIC4 CLIC4 LOC100730738 LOC100730738 GABRB1 GABRB1 ANO10 ANO10 GABRE GABRE CLIC1 CLIC1 H0W682_CAVPO H0W682_CAVPO GABRA2 GABRA2 TTYH2 TTYH2 BEST4 BEST4 GLRA4 GLRA4 GABRG1 GABRG1 LOC100726159 LOC100726159 GABRB2 GABRB2 LOC100727821 LOC100727821 CLCA1 CLCA1 CLCA2 CLCA2 SLC26A8 SLC26A8 CLCN1 CLCN1 ANO5 ANO5 GLRA1 GLRA1 SLC17A6 SLC17A6 GABRR3 GABRR3 CFTR CFTR GLRA3 GLRA3 GABRQ GABRQ GABRR2 GABRR2 GABRR1 GABRR1 Nmur2 Nmur2 CLCN5 CLCN5 GABRA6 GABRA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (789 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (576 aa)
PACC1Proton activated chloride channel 1. (350 aa)
CLCN2Chloride channel protein 2; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport (By similarity). Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity); Belongs [...] (889 aa)
SLC17A8Solute carrier family 17 member 8. (476 aa)
SLC1A4Solute carrier family 1 member 4. (532 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (246 aa)
ANO8Anoctamin. (1034 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (566 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
ANO3Anoctamin. (981 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
ANO9Anoctamin. (746 aa)
SLC26A7Anion exchange transporter. (656 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (505 aa)
LOC100727546VWFA domain-containing protein. (923 aa)
CLCC1Chloride channel CLIC like 1. (529 aa)
ANO2Anoctamin. (1003 aa)
CLCN3H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily. (865 aa)
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (505 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
BEST3Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (673 aa)
ANO4Anoctamin. (955 aa)
ENSCPOP00000030667Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (245 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
CLCN4Chloride channel protein. (747 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (252 aa)
Ttyh3Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (524 aa)
ANO6Anoctamin. (922 aa)
ANO1Anoctamin. (1011 aa)
TTYH1Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (380 aa)
CLCN6Chloride channel protein. (899 aa)
CLCN7Chloride channel protein. (804 aa)
ENSCPOP00000025593Uncharacterized protein. (180 aa)
CLIC3Chloride intracellular channel 3. (237 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
LOC100730738Chloride channel protein. (729 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (419 aa)
ANO10Anoctamin. (661 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (482 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
H0W682_CAVPOProtein tweety homolog; Probable chloride channel. (108 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
TTYH2Protein tweety homolog; Probable chloride channel. (533 aa)
BEST4Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (461 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (384 aa)
LOC100726159VWFA domain-containing protein. (911 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
LOC100727821VWFA domain-containing protein. (923 aa)
CLCA1Chloride channel accessory 1. (913 aa)
CLCA2Chloride channel accessory 2. (861 aa)
SLC26A8Testis anion transporter 1. (948 aa)
CLCN1Chloride channel protein. (990 aa)
ANO5Anoctamin. (886 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
SLC17A6Solute carrier family 17 member 6. (566 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (617 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (480 aa)
Nmur2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (403 aa)
CLCN5H(+)/Cl(-) exchange transporter 5; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 5/CLCN5 subfamily. (787 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (18%) [HD]