STRINGSTRING
LOC100717473 LOC100717473 LOC100713271 LOC100713271 PLIN1 PLIN1 TMEM159 TMEM159 SPART SPART ENSCPOP00000024925 ENSCPOP00000024925 HILPDA HILPDA CKAP4 CKAP4 HSD17B13 HSD17B13 C18orf32 C18orf32 Cav2 Cav2 METTL7A METTL7A AIFM2 AIFM2 KATNA1 KATNA1 CAV1 CAV1 ABHD5 ABHD5 ENSCPOP00000028762 ENSCPOP00000028762 LPCAT1 LPCAT1 SCCPDH SCCPDH EDA EDA RAB18 RAB18 TMEM135 TMEM135 ENSCPOP00000031025 ENSCPOP00000031025 HSD17B11 HSD17B11 ENSCPOP00000031164 ENSCPOP00000031164 SIGMAR1 SIGMAR1 REPIN1 REPIN1 LOC100721835 LOC100721835 PLIN5 PLIN5 ACSL3 ACSL3 AQP10 AQP10 IRAK1 IRAK1 Gapdh Gapdh PLIN3 PLIN3 Rap1b Rap1b LOC100730472 LOC100730472 RAB7A RAB7A RBP1 RBP1 VCP VCP TRAF6 TRAF6 APOB APOB ZW10 ZW10 PNPLA2 PNPLA2 Anxa2 Anxa2 VPS13A VPS13A ATG2B ATG2B RSAD2 RSAD2 EHD1 EHD1 TSC1 TSC1 DGAT2 DGAT2 HSPA4 HSPA4 PNPLA1 PNPLA1 NSDHL NSDHL LPCAT2 LPCAT2 DHRS3 DHRS3 ACSL4 ACSL4 ABHD4 ABHD4 Rdh10 Rdh10 SDR16C5 SDR16C5 PNPLA7 PNPLA7 PNPLA4 PNPLA4 BCAP31 BCAP31 ATG2A ATG2A PNPLA5 PNPLA5 FAF2 FAF2 Ces1d Ces1d HSD11B2 HSD11B2 PITPNM1 PITPNM1 Aqp7 Aqp7 LDAH LDAH AKAP1 AKAP1 LSS LSS ZFYVE1 ZFYVE1 METTL7B METTL7B H0VU94_CAVPO H0VU94_CAVPO H0VW66_CAVPO H0VW66_CAVPO H0VX85_CAVPO H0VX85_CAVPO CYB5R3 CYB5R3 PNPLA3 PNPLA3 CHKA CHKA LOC100735818 LOC100735818 AUP1 AUP1 LOC100732570 LOC100732570 CIDEA CIDEA PRPF19 PRPF19 CIDEC CIDEC ENSCPOP00000021806 ENSCPOP00000021806 Plin2 Plin2 LIPE LIPE RAB3GAP1 RAB3GAP1 UBE2G2 UBE2G2 CLDN11 CLDN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100717473Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa)
LOC100713271Uncharacterized protein. (165 aa)
PLIN1Perilipin; Belongs to the perilipin family. (515 aa)
TMEM159Transmembrane protein 159. (156 aa)
SPARTSpartin. (666 aa)
ENSCPOP00000024925COesterase domain-containing protein. (295 aa)
HILPDAHypoxia inducible lipid droplet associated. (64 aa)
CKAP4Cytoskeleton associated protein 4. (527 aa)
HSD17B13Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
C18orf32Chromosome 18 open reading frame 32. (75 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (125 aa)
METTL7AMethyltransferase like 7A. (290 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (492 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ABHD5Abhydrolase domain containing 5. (380 aa)
ENSCPOP00000028762Uncharacterized protein. (107 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (486 aa)
SCCPDHSaccharopine dehydrogenase (putative). (430 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (390 aa)
RAB18RAB18, member RAS oncogene family. (206 aa)
TMEM135Transmembrane protein 135. (411 aa)
ENSCPOP00000031025SAC domain-containing protein. (814 aa)
HSD17B11Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
ENSCPOP00000031164Perilipin; Belongs to the perilipin family. (376 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1; Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. [...] (223 aa)
REPIN1Replication initiator 1. (612 aa)
LOC100721835Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
PLIN5Perilipin; Belongs to the perilipin family. (458 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
AQP10Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (301 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (353 aa)
PLIN3Perilipin; Belongs to the perilipin family. (436 aa)
Rap1bUncharacterized protein. (184 aa)
LOC100730472Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RBP1Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (543 aa)
APOBApolipoprotein B. (4479 aa)
ZW10Zw10 kinetochore protein. (778 aa)
PNPLA2Patatin like phospholipase domain containing 2. (486 aa)
Anxa2Annexin. (339 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3051 aa)
ATG2BAutophagy related 2B. (2081 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (358 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
TSC1TSC complex subunit 1. (1166 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
HSPA4Heat shock protein family A (Hsp70) member 4. (821 aa)
PNPLA1Patatin like phospholipase domain containing 1. (554 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (361 aa)
LPCAT2Lysophosphatidylcholine acyltransferase 2. (499 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (707 aa)
ABHD4Abhydrolase domain containing 4. (335 aa)
Rdh10Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
PNPLA7Patatin like phospholipase domain containing 7. (1341 aa)
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
BCAP31B cell receptor associated protein 31. (246 aa)
ATG2AAutophagy related 2A. (1904 aa)
PNPLA5Patatin like phospholipase domain containing 5. (384 aa)
FAF2Fas associated factor family member 2. (418 aa)
Ces1dCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (395 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1244 aa)
Aqp7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (326 aa)
LDAHLipid droplet associated hydrolase. (341 aa)
AKAP1A-kinase anchoring protein 1. (860 aa)
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (777 aa)
METTL7BMethyltransferase like 7B. (244 aa)
H0VU94_CAVPOCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa)
H0VW66_CAVPOUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
H0VX85_CAVPOUncharacterized protein. (184 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
PNPLA3Patatin like phospholipase domain containing 3. (405 aa)
CHKACholine kinase alpha. (413 aa)
LOC100735818Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (439 aa)
LOC100732570AIG1-type G domain-containing protein. (289 aa)
CIDEACell death inducing DFFA like effector a. (220 aa)
PRPF19Pre-mRNA processing factor 19. (513 aa)
CIDECCell death inducing DFFA like effector c. (271 aa)
ENSCPOP00000021806Uncharacterized protein. (312 aa)
Plin2Perilipin; Belongs to the perilipin family. (446 aa)
LIPELipase E, hormone sensitive type. (802 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (987 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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