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| | LOC100732853 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (500 aa) |
| | HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (334 aa) |
| | ITPK1 | Inositol-tetrakisphosphate 1-kinase. (419 aa) |
| | SQLE | Squalene epoxidase. (569 aa) |
| | LOC100730472 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa) |
| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | Il4 | Interleukin-4. (144 aa) |
| | TM7SF2 | Transmembrane 7 superfamily member 2. (418 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | Cln8 | CLN8 transmembrane ER and ERGIC protein. (288 aa) |
| | LOC100721835 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | FDX1 | Ferredoxin 1. (124 aa) |
| | LOC100723118 | Aldo_ket_red domain-containing protein. (316 aa) |
| | ENSCPOP00000032185 | Aldedh domain-containing protein. (166 aa) |
| | APOA1 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa) |
| | RDH12 | Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | ABHD4 | Abhydrolase domain containing 4. (335 aa) |
| | AKR1B1 | Aldo-keto reductase family 1 member B. (316 aa) |
| | DHRS7 | Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (450 aa) |
| | NAPEPLD | N-acyl phosphatidylethanolamine phospholipase D. (395 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (566 aa) |
| | IMPA2 | Inositol-1-monophosphatase. (283 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (562 aa) |
| | DHRS3 | Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa) |
| | PPIP5K1 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1415 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (354 aa) |
| | RBP4 | Apolipoprotein D. (173 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa) |
| | SORD | Sorbitol dehydrogenase. (357 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1155 aa) |
| | MOXD1 | Monooxygenase DBH like 1. (616 aa) |
| | CEL | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (594 aa) |
| | Rdh11 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (434 aa) |
| | ALDH16A1 | Aldehyde dehydrogenase family 16 member A1. (804 aa) |
| | NSDHL | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (361 aa) |
| | LOC100717492 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | LOC100724620 | Aldo-keto reductase family 1 member C3. (323 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | GBA | Glucosylceramidase. (516 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | CYP7A1 | Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (496 aa) |
| | GCH1 | GTP cyclohydrolase 1. (222 aa) |
| | LIPC | Lipase C, hepatic type. (497 aa) |
| | SLC34A1 | Solute carrier family 34 member 1. (638 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | GK5 | Glycerol kinase 5; Belongs to the FGGY kinase family. (524 aa) |
| | APOB | Apolipoprotein B. (4479 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa) |
| | DGAT1 | O-acyltransferase. (493 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | SOAT2 | O-acyltransferase. (457 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (370 aa) |
| | MSMO1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa) |
| | PNPLA2 | Patatin like phospholipase domain containing 2. (486 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa) |
| | PMVK | Phosphomevalonate kinase. (192 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1052 aa) |
| | ANGPTL3 | Angiopoietin like 3. (421 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) |
| | DPAGT1 | Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1. (408 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (822 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | ACPP | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (340 aa) |
| | LOC100733616 | Uncharacterized protein; Belongs to the cytochrome P450 family. (319 aa) |
| | H0V8N6_CAVPO | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (191 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | INPP5K | Inositol polyphosphate-5-phosphatase K. (461 aa) |
| | LOC100732008 | PKS_ER domain-containing protein. (375 aa) |
| | CUBN | Cubilin. (3557 aa) |
| | APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (298 aa) |
| | HNF1A | HNF1 homeobox A. (628 aa) |
| | CLN6 | CLN6 transmembrane ER protein. (310 aa) |
| | DHRS13 | Dehydrogenase/reductase 13. (378 aa) |
| | FDFT1 | Farnesyl-diphosphate farnesyltransferase 1. (417 aa) |
| | IP6K2 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (449 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1600 aa) |
| | QDPR | Quinoid dihydropteridine reductase. (242 aa) |
| | IDH2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa) |
| | MTMR2 | Myotubularin related protein 2. (643 aa) |
| | NAAA | N-acylethanolamine-hydrolyzing acid amidase subunit alpha; Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N- myristoylethanolamine > N-stearoylethanolamine > N-oleoylethanolamine > N-linoleoylethanolamine > N-arachidonoylethanolamine. (347 aa) |
| | Nudt4 | Nudix hydrolase domain-containing protein. (147 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | INPP5B | Inositol polyphosphate-5-phosphatase B. (983 aa) |
| | ITPKC | Kinase; Belongs to the inositol phosphokinase (IPK) family. (679 aa) |
| | ABCA1 | ATP binding cassette subfamily A member 1. (2200 aa) |
| | INPP5E | Inositol polyphosphate-5-phosphatase E. (646 aa) |
| | GRK3 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (673 aa) |
| | Plpp1 | Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these b [...] (284 aa) |
| | MYOF | Myoferlin. (2033 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | TKFC | Triokinase and FMN cyclase. (578 aa) |
| | DYSF | Dysferlin. (2103 aa) |
| | TMEM130 | Transmembrane protein 130. (345 aa) |
| | Ces1d | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (395 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (652 aa) |
| | CETP | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (492 aa) |
| | IPPK | Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (489 aa) |
| | MTMR7 | Myotubularin related protein 7. (640 aa) |
| | CDCP2 | CUB domain containing protein 2. (399 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4- dienoyl-CoA reductase activity. (302 aa) |
| | TKTL1 | Transketolase like 1. (597 aa) |
| | SRD5A3 | Steroid 5 alpha-reductase 3. (318 aa) |
| | RDH13 | Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa) |
| | SPHK1 | Sphingosine kinase 1. (386 aa) |
| | APLP2 | Amyloid beta precursor like protein 2. (760 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2337 aa) |
| | TPI1 | Triosephosphate isomerase. (249 aa) |
| | INPP5J | Inositol polyphosphate-5-phosphatase J. (1015 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. (527 aa) |
| | EBP | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; Catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers; Belongs to the EBP family. (229 aa) |
| | MIOX | Myo-inositol oxygenase. (285 aa) |
| | APOA5 | Apolipoprotein A5. (429 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2427 aa) |
| | CYP51A1 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (248 aa) |
| | BCO1 | Beta-carotene oxygenase 1. (557 aa) |
| | APOF | Apolipoprotein F. (321 aa) |
| | ASAH2 | Neutral ceramidase. (752 aa) |
| | LEPR | Leptin receptor. (1174 aa) |
| | INPP5A | Inositol polyphosphate-5-phosphatase A. (390 aa) |
| | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (461 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (900 aa) |
| | IDH3B | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa) |
| | APOA2 | Apolipoprotein A2. (101 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (352 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | Shpk | FGGY_N domain-containing protein. (476 aa) |
| | CYP1A1 | Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (516 aa) |
| | DHCR24 | 24-dehydrocholesterol reductase. (516 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (686 aa) |
| | H0VU94_CAVPO | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa) |
| | PGP | Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa) |
| | H0VW66_CAVPO | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1235 aa) |
| | RDH8 | Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa) |
| | LOC100725498 | Aldo_ket_red domain-containing protein. (315 aa) |
| | SLC5A3 | Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa) |
| | Cebpa | Uncharacterized protein. (158 aa) |
| | CYB5R3 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa) |
| | H0W0J6_CAVPO | Uncharacterized protein. (384 aa) |
| | SPR | Sepiapterin reductase. (262 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (486 aa) |
| | FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial. (493 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (509 aa) |
| | SULT2B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (335 aa) |
| | CHKA | Choline kinase alpha. (413 aa) |
| | CYP1A2 | Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (515 aa) |
| | PLPP2 | Phospholipid phosphatase 2. (260 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa) |
| | LOC100734190 | Uncharacterized protein. (369 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa) |
| | LOC100735818 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa) |
| | DBH | Dopamine beta-hydroxylase. (616 aa) |
| | SCAP | SREBF chaperone. (1260 aa) |
| | ISYNA1 | Inositol-3-phosphate synthase 1. (559 aa) |
| | LCAT | Lecithin-cholesterol acyltransferase. (441 aa) |
| | ALDH3B1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa) |
| | RDH5 | Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | TKTL2 | Transketolase like 2. (627 aa) |
| | LOC100734586 | Nudix hydrolase domain-containing protein. (170 aa) |
| | IMPA1 | Inositol-1-monophosphatase. (277 aa) |
| | LOC100721923 | Nudix hydrolase domain-containing protein. (164 aa) |
| | H0WAF5_CAVPO | Iso_dh domain-containing protein. (332 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (273 aa) |
| | APOC1 | Apolipoprotein C1. (95 aa) |
| | GDPD3 | Glycerophosphodiester phosphodiesterase domain containing 3. (303 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (315 aa) |
| | RETSAT | Retinol saturase. (610 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | Plpp3 | acidPPc domain-containing protein. (312 aa) |
| | H0WCC9_CAVPO | Uncharacterized protein. (384 aa) |
| | LOC100725076 | Iso_dh domain-containing protein. (377 aa) |
| | APP | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (770 aa) |
| | IMPAD1 | Inositol monophosphatase domain containing 1. (355 aa) |
| | LDLR | Low density lipoprotein receptor. (807 aa) |
| | NFE2L1 | Nuclear factor, erythroid 2 like 1. (743 aa) |
| | TPK1 | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (243 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (407 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) |
| | RDH16 | Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | SYNJ1 | Synaptojanin 1. (1607 aa) |
| | SDR9C7 | Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | ALDH3A2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | PPIP5K2 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1237 aa) |
| | DPM1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa) |
| | ENSCPOP00000022046 | Thiolase_N domain-containing protein. (103 aa) |
| | LIPE | Lipase E, hormone sensitive type. (802 aa) |
| | EPHX1 | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (455 aa) |
| | IDH3G | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa) |
| | GDE1 | Glycerophosphodiester phosphodiesterase 1. (331 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (66 aa) |
| | VLDLR | Very low density lipoprotein receptor. (848 aa) |
| | ACO2 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa) |
| | GDPD1 | Glycerophosphodiester phosphodiesterase domain containing 1. (314 aa) |
| | NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (285 aa) |
| | Lbr | Tudor domain-containing protein. (133 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | ABCA5 | ATP binding cassette subfamily A member 5. (1593 aa) |
| | PSORS1C2 | Psoriasis susceptibility 1 candidate 2. (138 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | LOC100717473 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa) |
| | HDLBP | High density lipoprotein binding protein. (1399 aa) |
| | DHDDS | Alkyl transferase; Belongs to the UPP synthase family. (334 aa) |
| | TSKU | Tsukushi, small leucine rich proteoglycan. (364 aa) |
| | IDI1 | Isopentenyl-diphosphate delta isomerase 1. (227 aa) |
| | Gk | Uncharacterized protein; Belongs to the FGGY kinase family. (559 aa) |
| | PON1 | Paraoxonase 1. (363 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa) |
| | ENSCPOP00000024925 | COesterase domain-containing protein. (295 aa) |
| | ENSCPOP00000024929 | SCP2 domain-containing protein. (143 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (493 aa) |
| | SPTSSB | Serine palmitoyltransferase small subunit B. (76 aa) |
| | LRP1 | LDL receptor related protein 1. (4508 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (433 aa) |
| | NUDT3 | Nudix hydrolase 3. (162 aa) |
| | SPHK2 | Sphingosine kinase 2. (655 aa) |
| | INPP4B | Inositol polyphosphate-4-phosphatase type II B. (939 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1267 aa) |
| | Insig2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | AKR1E2 | Aldo-keto reductase family 1 member E2. (330 aa) |
| | ENSCPOP00000026343 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (214 aa) |
| | INPP1 | Inositol polyphosphate-1-phosphatase. (526 aa) |
| | COQ2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (372 aa) |
| | Aldh2 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (521 aa) |
| | GALK1 | Galactokinase 1. (392 aa) |
| | AKR1A1 | Aldo-keto reductase family 1 member A1. (325 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa) |
| | TTR | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (131 aa) |
| | SOAT1 | O-acyltransferase. (543 aa) |
| | FECH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (424 aa) |
| | IP6K3 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (401 aa) |
| | SULT1E1 | Sulfotransferase 1E1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesteroland xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine (By similarity). (296 aa) |
| | PNLIP | Pancreatic triacylglycerol lipase. (428 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (890 aa) |
| | Scnn1b | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa) |
| | PCTP | Phosphatidylcholine transfer protein. (214 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | OCRL | OCRL inositol polyphosphate-5-phosphatase. (900 aa) |
| | RPE65 | Retinoid isomerohydrolase RPE65. (490 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa) |
| | GPD2 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (744 aa) |
| | IPMK | Kinase; Belongs to the inositol phosphokinase (IPK) family. (377 aa) |
| | AWAT2 | Acyl-CoA wax alcohol acyltransferase 2. (303 aa) |
| | GBA2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (908 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | PNPLA4 | Patatin like phospholipase domain containing 4. (253 aa) |
| | LIMA1 | LIM domain and actin binding 1. (755 aa) |
| | SDR16C5 | Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa) |
| | LOC100716515 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (522 aa) |
| | THTPA | Thiamine triphosphatase. (231 aa) |
| | Rdh10 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa) |
| | SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (298 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1149 aa) |
| | LOC100727028 | PKS_ER domain-containing protein. (382 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (367 aa) |
| | BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1. (331 aa) |
| | PTAFR | Platelet-activating factor receptor; Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. (342 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (102 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (185 aa) |
| | SPTSSA | Serine palmitoyltransferase small subunit A. (71 aa) |
| | ENSCPOP00000029971 | Aldedh domain-containing protein. (216 aa) |
| | PTS | 6-pyruvoyl tetrahydrobiopterin synthase. (145 aa) |
| | SYNJ2 | Synaptojanin 2. (1489 aa) |
| | DPM2 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa) |
| | LOC100732581 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | ACER3 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa) |
