STRINGSTRING
PDP2 PDP2 PTPN5 PTPN5 PPM1H PPM1H PTPRK PTPRK PPP4R3B PPP4R3B PPP2R5D PPP2R5D PPM1M PPM1M SDHAF2 SDHAF2 PTPRF PTPRF PTPN3 PTPN3 PPP3CA PPP3CA Dusp15 Dusp15 SSH3 SSH3 LOC100734047 LOC100734047 PPP3CB PPP3CB CDC25B CDC25B RPAP2 RPAP2 PTPN13 PTPN13 PTPN2 PTPN2 DUSP7 DUSP7 PTPDC1 PTPDC1 STYXL1 STYXL1 TTC38 TTC38 CDC14C CDC14C PPP1R15B PPP1R15B PPM1L PPM1L PTPRR PTPRR PPP1CC PPP1CC BTRC BTRC PPP2CB PPP2CB RNGTT RNGTT H0V4N6_CAVPO H0V4N6_CAVPO CDKN3 CDKN3 PPM1J PPM1J PPP1R12A PPP1R12A PPM1G PPM1G PPP4R3A PPP4R3A PTPRD PTPRD MTMR4 MTMR4 PTPRG PTPRG PTPN7 PTPN7 ACP1 ACP1 CTDP1 CTDP1 PPP2R3A PPP2R3A PPM1A PPM1A MTMR3 MTMR3 DUSP27 DUSP27 SSU72 SSU72 UBASH3B UBASH3B PTPN18 PTPN18 PPP4R1 PPP4R1 PHLPP1 PHLPP1 Dusp21 Dusp21 DUSP12 DUSP12 PPP3CC PPP3CC PPM1D PPM1D PPP2R5C PPP2R5C DUSP9 DUSP9 DUSP26 DUSP26 STYX STYX DUSP8 DUSP8 EPM2A EPM2A PTPN4 PTPN4 DUSP14 DUSP14 PPP3R1 PPP3R1 MTM1 MTM1 RPRD1B RPRD1B PTPN21 PTPN21 PPM1E PPM1E PTPRU PTPRU DUSP23 DUSP23 FBXW11 FBXW11 Dusp3 Dusp3 CDC14A CDC14A PTP4A3 PTP4A3 PTPRM PTPRM PTPRQ PTPRQ PGAM5 PGAM5 DUSP16 DUSP16 DUSP18 DUSP18 CTDSP1 CTDSP1 UBLCP1 UBLCP1 DAPP1 DAPP1 PPM1N PPM1N NCEH1 NCEH1 PTPRC PTPRC EYA1 EYA1 Ppm1b Ppm1b PDXP PDXP PTPRE PTPRE SSH1 SSH1 PTPN6 PTPN6 DUSP1 DUSP1 PTPN14 PTPN14 CTTNBP2NL CTTNBP2NL DUSP4 DUSP4 PTP4A1 PTP4A1 CDC25A CDC25A PPP4R2 PPP4R2 STK11 STK11 SSH2 SSH2 PTPRA PTPRA PPP6C PPP6C PPP2R5E PPP2R5E DUSP22 DUSP22 Fndc10 Fndc10 DUSP19 DUSP19 PTPRJ PTPRJ PHPT1 PHPT1 PPP2R1B PPP2R1B PTPRB PTPRB PPP2CA PPP2CA DUSP6 DUSP6 PPM1K PPM1K PPP1CB PPP1CB CTDSP2 CTDSP2 PPP2R5A PPP2R5A PPP5C PPP5C PTPRZ1 PTPRZ1 PPP1CA PPP1CA DUSP13 DUSP13 NCK1 NCK1 PTPN1 PTPN1 CTDNEP1 CTDNEP1 PTPMT1 PTPMT1 ENSCPOP00000021796 ENSCPOP00000021796 H0WDD9_CAVPO H0WDD9_CAVPO PTPN23 PTPN23 PPP4R3C PPP4R3C H0WAJ1_CAVPO H0WAJ1_CAVPO TNS2 TNS2 DUSP28 DUSP28 PTEN PTEN PPTC7 PPTC7 CTDSPL2 CTDSPL2 ACP4 ACP4 LOC100721187 LOC100721187 BCL2 BCL2 H0W160_CAVPO H0W160_CAVPO DUPD1 DUPD1 DUSP5 DUSP5 DUSP2 DUSP2 PPP2R5B PPP2R5B PDPR PDPR Ptprh Ptprh TIMM50 TIMM50 PGP PGP PPM1F PPM1F PPP2R2A PPP2R2A DUSP11 DUSP11 ILKAP ILKAP PTPRT PTPRT PTPRO PTPRO PTPN11 PTPN11 EYA2 EYA2 DUSP10 DUSP10 PTPRS PTPRS EYA3 EYA3 RPRD1A RPRD1A PHLPP2 PHLPP2 PTPN9 PTPN9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDP2Pyruvate dehyrogenase phosphatase catalytic subunit 2. (530 aa)
PTPN5Protein tyrosine phosphatase non-receptor type 5. (541 aa)
PPM1HProtein phosphatase, Mg2+/Mn2+ dependent 1H. (504 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1455 aa)
PPP4R3BProtein phosphatase 4 regulatory subunit 3B. (802 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
PPM1MProtein phosphatase, Mg2+/Mn2+ dependent 1M. (405 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (164 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1908 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (912 aa)
PPP3CASerine/threonine-protein phosphatase. (518 aa)
Dusp15Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (236 aa)
SSH3Slingshot protein phosphatase 3. (652 aa)
LOC100734047Uncharacterized protein. (567 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
CDC25BCell division cycle 25B. (579 aa)
RPAP2RNA polymerase II associated protein 2. (574 aa)
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2480 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (364 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
PTPDC1Protein tyrosine phosphatase domain containing 1. (755 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (317 aa)
TTC38Tetratricopeptide repeat domain 38. (468 aa)
CDC14CCell division cycle 14C. (453 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (702 aa)
PPM1LProtein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (582 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (589 aa)
H0V4N6_CAVPOUncharacterized protein. (371 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
PPM1JProtein phosphatase, Mg2+/Mn2+ dependent 1J. (505 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1069 aa)
PPM1GProtein phosphatase, Mg2+/Mn2+ dependent 1G. (540 aa)
PPP4R3AProtein phosphatase 4 regulatory subunit 3A. (733 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1767 aa)
MTMR4Myotubularin related protein 4. (1189 aa)
PTPRGProtein tyrosine phosphatase receptor type G. (1438 aa)
PTPN7Protein tyrosine phosphatase non-receptor type 7. (360 aa)
ACP1Acid phosphatase 1. (158 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (956 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1122 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
MTMR3Myotubularin related protein 3. (1221 aa)
DUSP27Dual specificity phosphatase 27, atypical; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1080 aa)
SSU72SSU72 homolog, RNA polymerase II CTD phosphatase. (194 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (638 aa)
PTPN18Protein tyrosine phosphatase non-receptor type 18. (451 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (942 aa)
PHLPP1PH domain and leucine rich repeat protein phosphatase 1. (1249 aa)
Dusp21Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (189 aa)
DUSP12Dual specificity phosphatase 12. (338 aa)
PPP3CCSerine/threonine-protein phosphatase. (481 aa)
PPM1DProtein phosphatase, Mg2+/Mn2+ dependent 1D. (601 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (589 aa)
DUSP9Dual specificity phosphatase 9. (265 aa)
DUSP26Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
STYXSerine/threonine/tyrosine interacting protein. (223 aa)
DUSP8Dual specificity phosphatase 8. (609 aa)
EPM2AEPM2A glucan phosphatase, laforin. (193 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (914 aa)
DUSP14Dual specificity phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (198 aa)
PPP3R1Uncharacterized protein. (169 aa)
MTM1Myotubularin 1. (599 aa)
RPRD1BRegulation of nuclear pre-mRNA domain containing 1B. (326 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1166 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (748 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1504 aa)
DUSP23Dual specificity phosphatase 23. (150 aa)
FBXW11F-box and WD repeat domain containing 11. (530 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
CDC14ACell division cycle 14A. (596 aa)
PTP4A3Protein tyrosine phosphatase 4A3. (173 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1445 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2192 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (288 aa)
DUSP16Dual specificity phosphatase 16. (662 aa)
DUSP18Dual specificity phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
CTDSP1CTD small phosphatase 1. (261 aa)
UBLCP1Ubiquitin like domain containing CTD phosphatase 1. (318 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
PPM1NProtein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (393 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1307 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
Ppm1bPPM-type phosphatase domain-containing protein. (479 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (292 aa)
PTPREReceptor-type tyrosine-protein phosphatase. (723 aa)
SSH1Slingshot protein phosphatase 1. (1053 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1182 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (638 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
PTP4A1Protein tyrosine phosphatase 4A1. (173 aa)
CDC25ACell division cycle 25A. (519 aa)
PPP4R2Protein phosphatase 4 regulatory subunit 2. (416 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (435 aa)
SSH2Slingshot protein phosphatase 2. (1444 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (799 aa)
PPP6CSerine/threonine-protein phosphatase. (305 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (172 aa)
Fndc10Uncharacterized protein. (302 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (229 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1311 aa)
PHPT1Phosphohistidine phosphatase 1. (125 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (696 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2215 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
PPM1KProtein phosphatase, Mg2+/Mn2+ dependent 1K. (372 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
PPP5CSerine/threonine-protein phosphatase. (533 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (1433 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
DUSP13Dual specificity phosphatase 13; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (248 aa)
NCK1Cytoplasmic protein. (377 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (432 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (210 aa)
PTPMT1Protein tyrosine phosphatase mitochondrial 1. (169 aa)
ENSCPOP00000021796Tyrosine-protein phosphatase domain-containing protein. (141 aa)
H0WDD9_CAVPOUncharacterized protein. (194 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1623 aa)
PPP4R3CProtein phosphatase 4 regulatory subunit 3C. (757 aa)
H0WAJ1_CAVPOUncharacterized protein. (69 aa)
TNS2Tensin 2. (1396 aa)
DUSP28Dual specificity phosphatase 28. (178 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (298 aa)
CTDSPL2CTD small phosphatase like 2. (403 aa)
ACP4Acid phosphatase 4; Belongs to the histidine acid phosphatase family. (424 aa)
LOC100721187Uncharacterized protein. (489 aa)
BCL2BCL2 apoptosis regulator. (183 aa)
H0W160_CAVPOUncharacterized protein. (589 aa)
DUPD1Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (375 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
PDPRPyruvate dehydrogenase phosphatase regulatory subunit. (838 aa)
PtprhUncharacterized protein. (459 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (353 aa)
PGPPhosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (458 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (448 aa)
DUSP11Dual specificity phosphatase 11. (326 aa)
ILKAPILK associated serine/threonine phosphatase. (391 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1395 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (588 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (529 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1805 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (497 aa)
RPRD1ARegulation of nuclear pre-mRNA domain containing 1A. (307 aa)
PHLPP2PH domain and leucine rich repeat protein phosphatase 2. (1292 aa)
PTPN9Protein tyrosine phosphatase non-receptor type 9. (536 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (14%) [HD]