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STX1B STX1B H0VSR6_CAVPO H0VSR6_CAVPO RPH3A RPH3A STX4 STX4 UNC13A UNC13A LOC100734527 LOC100734527 SYDE1 SYDE1 NLGN1 NLGN1 STXBP2 STXBP2 STX19 STX19 SLC18A3 SLC18A3 SYT12 SYT12 SLC6A1 SLC6A1 GABRA2 GABRA2 DOC2A DOC2A SLC6A5 SLC6A5 ICA1 ICA1 DOC2B DOC2B CACNA1A CACNA1A SLC6A3 SLC6A3 SLC29A4 SLC29A4 DGKI DGKI SYNJ1 SYNJ1 CPLX4 CPLX4 SLC6A13 SLC6A13 SPTBN2 SPTBN2 SLC17A6 SLC17A6 SYN1 SYN1 SLC6A17 SLC6A17 TH TH ERC2 ERC2 Slc6a8 Slc6a8 STX2 STX2 SLC1A7 SLC1A7 RIMS4 RIMS4 NAPA NAPA SLC6A4 SLC6A4 SLC6A18 SLC6A18 TRIM9 TRIM9 SV2A SV2A SLC22A3 SLC22A3 SYT4 SYT4 PCLO PCLO DRD2 DRD2 SYT5 SYT5 SLC17A8 SLC17A8 ERC1 ERC1 SLC32A1 SLC32A1 SV2C SV2C SNAP47 SNAP47 SYN2 SYN2 SV2B SV2B SLC6A11 SLC6A11 UNC13C UNC13C SLC1A2 SLC1A2 XBP1 XBP1 SYN3 SYN3 RIMS2 RIMS2 DVL1 DVL1 SLC17A7 SLC17A7 NF1 NF1 CADPS2 CADPS2 PPT1 PPT1 SLC29A1 SLC29A1 CACNA1B CACNA1B SYT9 SYT9 SNAP23 SNAP23 SLC18A2 SLC18A2 LRRC1 LRRC1 STX1A STX1A SYT2 SYT2 SNAP29 SNAP29 SLC6A15 SLC6A15 NR4A1 NR4A1 SNAP25 SNAP25 LIN7B LIN7B SLC6A2 SLC6A2 SLC1A6 SLC1A6 SYT1 SYT1 SLC18A1 SLC18A1 SNAP91 SNAP91 Cadps Cadps RIMS3 RIMS3 SLC22A2 SLC22A2 PRRT2 PRRT2 LIN7A LIN7A NRXN2 NRXN2 SLC29A2 SLC29A2 ASIC1 ASIC1 PDZD11 PDZD11 PAK1 PAK1 SLC6A6 SLC6A6 SYT8 SYT8 UNC13B UNC13B CPLX3 CPLX3 SLC6A12 SLC6A12 NT5DC2 NT5DC2 RPH3AL RPH3AL STXBP3 STXBP3 PSEN1 PSEN1 CPLX1 CPLX1 SLC6A7 SLC6A7 SNCA SNCA KCNJ10 KCNJ10 STXBP1 STXBP1 SYNGR3 SYNGR3 SYT6 SYT6 Rims1 Rims1 CPLX2 CPLX2 STX11 STX11 SCRIB SCRIB ENSCPOP00000027747 ENSCPOP00000027747 STX3 STX3 RAB3A RAB3A ATP1A2 ATP1A2 SNAPIN SNAPIN LIN7C LIN7C Vamp2 Vamp2 PPFIA3 PPFIA3 Cln8 Cln8 NT5DC3 NT5DC3 CTBP2 CTBP2 SYT7 SYT7 NRXN3 NRXN3 Prkaca Prkaca SLC6A9 SLC6A9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
H0VSR6_CAVPOUncharacterized protein. (327 aa)
RPH3ARabphilin 3A. (667 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
UNC13AUnc-13 homolog A. (1650 aa)
LOC100734527Double C2-like domain-containing protein. (399 aa)
SYDE1Synapse defective Rho GTPase homolog 1. (723 aa)
NLGN1Neuroligin 1. (843 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
STX19Syntaxin 19; Belongs to the syntaxin family. (292 aa)
SLC18A3Solute carrier family 18 member A3. (533 aa)
SYT12Synaptotagmin 12. (421 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (589 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
DOC2ADouble C2-like domain-containing protein. (401 aa)
SLC6A5Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (764 aa)
ICA1Islet cell autoantigen 1. (482 aa)
DOC2BDouble C2 domain beta. (340 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
SLC29A4Solute carrier family 29 member 4. (524 aa)
DGKIDiacylglycerol kinase. (957 aa)
SYNJ1Synaptojanin 1. (1607 aa)
CPLX4Complexin 4. (160 aa)
SLC6A13Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (601 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2386 aa)
SLC17A6Solute carrier family 17 member 6. (566 aa)
SYN1Synapsin I. (690 aa)
SLC6A17Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
THTyrosine hydroxylase. (498 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (975 aa)
Slc6a8Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (286 aa)
SLC1A7Amino acid transporter. (574 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (253 aa)
NAPANSF attachment protein alpha. (295 aa)
SLC6A4Sodium-dependent serotonin transporter; Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner (By similarity); Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily. (612 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (605 aa)
TRIM9Tripartite motif containing 9. (786 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
SLC22A3Solute carrier family 22 member 3. (396 aa)
SYT4Synaptotagmin 4. (425 aa)
PCLOPiccolo presynaptic cytomatrix protein. (3548 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
SYT5Synaptotagmin 5. (386 aa)
SLC17A8Solute carrier family 17 member 8. (476 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1116 aa)
SLC32A1Solute carrier family 32 member 1. (526 aa)
SV2CSynaptic vesicle glycoprotein 2C. (727 aa)
SNAP47Synaptosome associated protein 47. (418 aa)
SYN2Synapsin II. (472 aa)
SV2BSynaptic vesicle glycoprotein 2B. (683 aa)
SLC6A11Solute carrier family 6 member 11. (640 aa)
UNC13CUnc-13 homolog C. (2198 aa)
SLC1A2Amino acid transporter. (573 aa)
XBP1X-box binding protein 1. (268 aa)
SYN3Synapsin III. (560 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1410 aa)
DVL1Dishevelled segment polarity protein 1. (698 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
NF1Neurofibromin 1. (2750 aa)
CADPS2Calcium dependent secretion activator 2. (1179 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (461 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa)
SYT9Synaptotagmin 9. (487 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
SLC18A2Solute carrier family 18 member A2. (516 aa)
LRRC1Leucine rich repeat containing 1. (458 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
SYT2Synaptotagmin 2. (421 aa)
SNAP29Synaptosome associated protein 29. (255 aa)
SLC6A15Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (733 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (205 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (626 aa)
SLC1A6Amino acid transporter. (560 aa)
SYT1Synaptotagmin 1. (422 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
SNAP91Synaptosome associated protein 91. (896 aa)
CadpsUncharacterized protein. (1363 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SLC22A2Solute carrier family 22 member 2. (514 aa)
PRRT2Proline rich transmembrane protein 2. (340 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (205 aa)
NRXN2Neurexin 2. (1613 aa)
SLC29A2Solute carrier family 29 member 2. (456 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa)
PDZD11PDZ domain containing 11. (140 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
SYT8Synaptotagmin 8. (398 aa)
UNC13BUnc-13 homolog B. (1959 aa)
CPLX3Complexin 3. (158 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (611 aa)
NT5DC25'-nucleotidase domain containing 2. (557 aa)
RPH3ALRabphilin 3A like (without C2 domains). (303 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CPLX1Complexin 1. (134 aa)
SLC6A7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (637 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
SYNGR3Synaptogyrin. (229 aa)
SYT6Synaptotagmin 6. (512 aa)
Rims1C2 domain-containing protein. (219 aa)
CPLX2Complexin 2. (134 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
SCRIBScribble planar cell polarity protein. (1653 aa)
ENSCPOP00000027747LAM_G_DOMAIN domain-containing protein. (151 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (288 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
Vamp2V-SNARE coiled-coil homology domain-containing protein. (164 aa)
PPFIA3PTPRF interacting protein alpha 3. (1194 aa)
Cln8CLN8 transmembrane ER and ERGIC protein. (288 aa)
NT5DC35'-nucleotidase domain containing 3. (497 aa)
CTBP2C-terminal binding protein 2. (978 aa)
SYT7Synaptotagmin 7. (556 aa)
NRXN3Neurexin 3. (1571 aa)
PrkacaUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (633 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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