STRINGSTRING
MYLK2 MYLK2 CHAT CHAT STAC3 STAC3 KIF1B KIF1B ERC1 ERC1 ETV5 ETV5 FCHSD2 FCHSD2 ERC2 ERC2 CHRNA3 CHRNA3 R3HDM1 R3HDM1 LOC100730761 LOC100730761 P2RX2 P2RX2 CHRNB1 CHRNB1 P2RX3 P2RX3 NTF3 NTF3 ADARB1 ADARB1 FCHSD1 FCHSD1 SLC5A7 SLC5A7 CHRM1 CHRM1 CACNA1A CACNA1A RIMBP2 RIMBP2 CHRNB4 CHRNB4 STXBP1 STXBP1 R3HDM2 R3HDM2 CHRNA1 CHRNA1 RAB3A RAB3A EGR3 EGR3 Chrnb2 Chrnb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYLK2Myosin light chain kinase 2. (593 aa)
CHATCholine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (621 aa)
STAC3SH3 and cysteine rich domain 3. (363 aa)
KIF1BKinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1792 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1116 aa)
ETV5ETS variant 5. (516 aa)
FCHSD2FCH and double SH3 domains 2. (764 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (975 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (506 aa)
R3HDM1R3H domain containing 1. (1127 aa)
LOC100730761Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
P2RX2P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity); Belongs to the P2X receptor family. (411 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (502 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
ADARB1Adenosine deaminase RNA specific B1. (603 aa)
FCHSD1FCH and double SH3 domains 1. (690 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (579 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa)
RIMBP2RIMS binding protein 2. (830 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (489 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
R3HDM2R3H domain containing 2. (1039 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
EGR3Early growth response 3. (388 aa)
Chrnb2Uncharacterized protein. (499 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.