STRINGSTRING
MYL6B MYL6B METTL21C METTL21C HIVEP3 HIVEP3 MSC MSC WNT3A WNT3A Foxp1 Foxp1 NUPR1 NUPR1 ANKRD2 ANKRD2 BTG2 BTG2 NFATC3 NFATC3 Pitx2 Pitx2 MYF6 MYF6 COL19A1 COL19A1 HLF HLF MAPK14 MAPK14 SIX4 SIX4 MEF2C MEF2C SELENON SELENON FOS FOS ATF3 ATF3 CACNA1S CACNA1S HLX HLX MYOD1 MYOD1 EGR1 EGR1 KEL KEL TCF21 TCF21 MYOG MYOG VRK3 VRK3 RTL5 RTL5 DLL1 DLL1 VGLL2 VGLL2 VAMP5 VAMP5 MEOX2 MEOX2 KLHL40 KLHL40 SCX SCX SOX11 SOX11 PHOX2B PHOX2B RYR1 RYR1 P2rx5 P2rx5 HOXD9 HOXD9 PAX7 PAX7 P2RX2 P2RX2 MET MET LMOD3 LMOD3 SMO SMO SVIL SVIL R3HDM1 R3HDM1 BCL9 BCL9 DNER DNER HOXD10 HOXD10 BARX2 BARX2 GTF3C5 GTF3C5 BIN3 BIN3 HMG20B HMG20B SNW1 SNW1 FLNB FLNB PAX5 PAX5 PPP3CA PPP3CA BCL9L BCL9L DMD DMD CNTNAP1 CNTNAP1 RB1 RB1 PPP3CB PPP3CB RIPOR2 RIPOR2 LEMD2 LEMD2 MYF5 MYF5 MYOZ2 MYOZ2 SRPK3 SRPK3 NPHS1 NPHS1 NEURL1 NEURL1 SKI SKI STAC3 STAC3 NF1 NF1 MEF2D MEF2D CHRND CHRND CDON CDON EP300 EP300 KLHL41 KLHL41 MED20 MED20 EOMES EOMES COPS2 COPS2 MYOZ1 MYOZ1 CITED2 CITED2 MYL6 MYL6 SHH SHH MYLK2 MYLK2 HOMER1 HOMER1 SMYD1 SMYD1 CASQ1 CASQ1 ZBTB18 ZBTB18 CDK5 CDK5 SGCE SGCE ZNF689 ZNF689 PITX1 PITX1 XK XK TAZ TAZ MYH15 MYH15 NR4A1 NR4A1 MYLPF MYLPF H0UZN0_CAVPO H0UZN0_CAVPO SOX8 SOX8 ANKRD1 ANKRD1 ASB2 ASB2 ACTA1 ACTA1 SAP30 SAP30 KLF5 KLF5 ANKRD33 ANKRD33 CFLAR CFLAR SIN3B SIN3B FOXP2 FOXP2 FOXN2 FOXN2 LEMD3 LEMD3 MYH14 MYH14 METTL8 METTL8 ENSCPOP00000030496 ENSCPOP00000030496 CCNT2 CCNT2 MEGF10 MEGF10 MBNL1 MBNL1 CFL2 CFL2 ENSCPOP00000029626 ENSCPOP00000029626 POPDC3 POPDC3 CRHR2 CRHR2 POPDC2 POPDC2 GPCPD1 GPCPD1 CHRNA1 CHRNA1 R3HDM2 R3HDM2 WNT10B WNT10B BVES BVES RXRG RXRG CAV1 CAV1 SIX1 SIX1 Cav2 Cav2 HEYL HEYL EGR2 EGR2 MYC MYC RCAN1 RCAN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL6BMyosin light chain 6B. (207 aa)
METTL21CMethyltransferase like 21C. (264 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2384 aa)
MSCMusculin. (207 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
Foxp1Fork-head domain-containing protein. (687 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (90 aa)
ANKRD2Ankyrin repeat domain 2. (328 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
NFATC3Nuclear factor of activated T cells 3. (1060 aa)
Pitx2Homeobox protein. (325 aa)
MYF6Myogenic factor 6. (242 aa)
COL19A1Collagen type XIX alpha 1 chain. (1120 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SIX4SIX homeobox 4. (766 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SELENONSelenoprotein N. (573 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ATF3Activating transcription factor 3. (181 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1867 aa)
HLXH2.0 like homeobox. (442 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (535 aa)
KELKell metallo-endopeptidase (Kell blood group). (706 aa)
TCF21Transcription factor 21. (179 aa)
MYOGMyogenin. (249 aa)
VRK3VRK serine/threonine kinase 3. (402 aa)
RTL5Retrotransposon Gag like 5. (608 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (607 aa)
VGLL2Vestigial like family member 2. (238 aa)
VAMP5Vesicle associated membrane protein 5. (100 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
KLHL40Kelch like family member 40. (624 aa)
SCXScleraxis bHLH transcription factor. (199 aa)
SOX11Transcription factor SOX. (377 aa)
PHOX2BPaired like homeobox 2B. (284 aa)
RYR1Ryanodine receptor 1. (4554 aa)
P2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (456 aa)
HOXD9Homeobox D9. (346 aa)
PAX7Paired box 7. (500 aa)
P2RX2P2X purinoceptor 2; Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle (By similarity); Belongs to the P2X receptor family. (411 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
LMOD3Leiomodin 3. (569 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
SVILSupervillin. (2237 aa)
R3HDM1R3H domain containing 1. (1127 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
DNERDelta/notch like EGF repeat containing. (741 aa)
HOXD10Homeobox D10. (340 aa)
BARX2BARX homeobox 2. (242 aa)
GTF3C5General transcription factor IIIC subunit 5. (519 aa)
BIN3Bridging integrator 3. (253 aa)
HMG20BHigh mobility group 20B. (318 aa)
SNW1SNW domain containing 1. (535 aa)
FLNBFilamin B. (2602 aa)
PAX5Paired box 5. (391 aa)
PPP3CASerine/threonine-protein phosphatase. (518 aa)
BCL9LBCL9 like. (1496 aa)
DMDDystrophin. (3613 aa)
CNTNAP1Contactin associated protein 1. (1374 aa)
RB1RB transcriptional corepressor 1. (840 aa)
PPP3CBSerine/threonine-protein phosphatase. (531 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1062 aa)
LEMD2LEM domain containing 2. (494 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MYOZ2Myozenin 2. (264 aa)
SRPK3SRSF protein kinase 3. (565 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1252 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
SKISKI proto-oncogene. (586 aa)
STAC3SH3 and cysteine rich domain 3. (363 aa)
NF1Neurofibromin 1. (2750 aa)
MEF2DMyocyte enhancer factor 2D. (514 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
CDONCell adhesion associated, oncogene regulated. (1265 aa)
EP300E1A binding protein p300. (2425 aa)
KLHL41Kelch like family member 41. (606 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
EOMESEomesodermin. (697 aa)
COPS2COP9 signalosome subunit 2. (443 aa)
MYOZ1Myozenin 1. (298 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
MYL6Myosin light chain 6. (151 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (447 aa)
MYLK2Myosin light chain kinase 2. (593 aa)
HOMER1Homer scaffold protein 1. (329 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
ZBTB18Zinc finger and BTB domain containing 18. (531 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SGCESarcoglycan epsilon. (401 aa)
ZNF689Zinc finger protein 689. (500 aa)
PITX1Homeobox protein. (311 aa)
XKXK-related protein. (443 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (262 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1926 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (170 aa)
H0UZN0_CAVPOUncharacterized protein. (763 aa)
SOX8SRY-box transcription factor 8. (462 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (640 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
SAP30Sin3A associated protein 30. (221 aa)
KLF5Kruppel like factor 5. (374 aa)
ANKRD33Ankyrin repeat domain 33. (332 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (442 aa)
SIN3BSIN3 transcription regulator family member B. (1097 aa)
FOXP2Forkhead box P2. (739 aa)
FOXN2Forkhead box N2. (429 aa)
LEMD3LEM domain containing 3. (838 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2034 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (386 aa)
ENSCPOP00000030496Uncharacterized protein. (736 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (734 aa)
MEGF10Multiple EGF like domains 10. (1148 aa)
MBNL1Muscleblind like splicing regulator 1. (387 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ENSCPOP00000029626Uncharacterized protein. (358 aa)
POPDC3Popeye domain containing 3. (291 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
POPDC2Popeye domain containing 2. (368 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (682 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (457 aa)
R3HDM2R3H domain containing 2. (1039 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (390 aa)
BVESBlood vessel epicardial substance. (359 aa)
RXRGRetinoid X receptor gamma. (499 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SIX1SIX homeobox 1. (284 aa)
Cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (125 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
EGR2Early growth response 2. (473 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
RCAN1Regulator of calcineurin 1. (249 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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