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KCNB2 KCNB2 KCNK1 KCNK1 CALM2 CALM2 KCND3 KCND3 KCNA10 KCNA10 KCNAB3 KCNAB3 CALM1 CALM1 KCNAB2 KCNAB2 KCNH1 KCNH1 KCNC2 KCNC2 DPP10 DPP10 KCNA1 KCNA1 AKAP9 AKAP9 KCNAB1 KCNAB1 KCNQ5 KCNQ5 Kcnj3 Kcnj3 KCNA7 KCNA7 KCNK2 KCNK2 ENSCPOP00000032059 ENSCPOP00000032059 KCND1 KCND1 DPP6 DPP6 Kcnj2 Kcnj2 LRRC55 LRRC55 KCNV2 KCNV2 KCNQ4 KCNQ4 H0V4J9_CAVPO H0V4J9_CAVPO KCNV1 KCNV1 CTTN CTTN KCNQ3 KCNQ3 KCNC1 KCNC1 KCNB1 KCNB1 KCNA2 KCNA2 Kcng2 Kcng2 KCND2 KCND2 H0VKV0_CAVPO H0VKV0_CAVPO KCNG3 KCNG3 KCNC4 KCNC4 Kcnmb2 Kcnmb2 HCN1 HCN1 KCNIP4 KCNIP4 CALM3 CALM3 KCNA4 KCNA4 KCNMA1 KCNMA1 AMIGO2 AMIGO2 KCNJ5 KCNJ5 KCNG4 KCNG4 KCNQ2 KCNQ2 LRRC38 LRRC38 KCNE1 KCNE1 KCNG1 KCNG1 KCNS1 KCNS1 KCNA6 KCNA6 KCNE2 KCNE2 KCNMB1 KCNMB1 KCNIP2 KCNIP2 HCN2 HCN2 HCN4 HCN4 KCNA5 KCNA5 HCN3 HCN3 KCNF1 KCNF1 KCNC3 KCNC3 KCNS2 KCNS2 KCNMB3 KCNMB3 KCNH2 KCNH2 SLC5A3 SLC5A3 KCNS3 KCNS3 KCNQ1 KCNQ1 KCNA3 KCNA3 LRRC52 LRRC52 KCNIP3 KCNIP3 KCNIP1 KCNIP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
KCNK1Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] (336 aa)
CALM2Calmodulin isoform 3; Belongs to the calmodulin family. (149 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (654 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (404 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (194 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
KCNH1Uncharacterized protein. (989 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (776 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
AKAP9A-kinase anchoring protein 9. (3887 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (908 aa)
Kcnj3IRK_C domain-containing protein. (194 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (469 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
ENSCPOP00000032059Uncharacterized protein; Belongs to the calmodulin family. (73 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (651 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
Kcnj2Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Blocked b [...] (427 aa)
LRRC55Leucine rich repeat containing 55. (328 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (558 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (699 aa)
H0V4J9_CAVPOUncharacterized protein. (291 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
CTTNCortactin. (550 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (860 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (855 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
Kcng2Ion_trans domain-containing protein; Belongs to the potassium channel family. (235 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
H0VKV0_CAVPOUncharacterized protein; Belongs to the calmodulin family. (139 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (417 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (594 aa)
Kcnmb2KcnmB2_inactiv domain-containing protein. (235 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (671 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (143 aa)
CALM3Calmodulin 3. (149 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (622 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1133 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (509 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (871 aa)
LRRC38Leucine rich repeat containing 38. (295 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (125 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (515 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (497 aa)
KCNA6Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. (491 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr). May associate with KCNQ2 and/or KCNQ3 and modulate the native M-t [...] (123 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (270 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (783 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1186 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (609 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (780 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (435 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (729 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (445 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (270 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr) (By similarity). (1144 aa)
SLC5A3Solute carrier family 5 member 3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (718 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (528 aa)
LRRC52Leucine rich repeat containing 52. (316 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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