22 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	Prkaca	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	ENSCPOP00000029566	Uncharacterized protein. (433 aa)
	EDN1	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (208 aa)
	TCP11	T-complex 11. (472 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	ENSCPOP00000024842	Uncharacterized protein. (173 aa)
	MYOM1	Myomesin 1. (1658 aa)
	ENSCPOP00000024015	Uncharacterized protein. (5460 aa)
	H0WBS2_CAVPO	Uncharacterized protein. (892 aa)
	Rab13	Uncharacterized protein. (203 aa)
	LOC100721539	Uncharacterized protein. (971 aa)
	GCG	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa)
	Mroh7	Uncharacterized protein. (1240 aa)
	MROH2A	Maestro heat like repeat family member 2A. (1675 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	GAL	Galanin and GMAP prepropeptide. (123 aa)
	MROH2B	Maestro heat like repeat family member 2B. (1558 aa)
	LCP1	Lymphocyte cytosolic protein 1. (627 aa)
	MROH8	Maestro heat like repeat family member 8. (1049 aa)
	EZR	Ezrin. (586 aa)
	MRO	Maestro. (247 aa)
	MROH1	Maestro heat like repeat family member 1. (1641 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	EDNRA	ENSCPOP00000028977	ENSCPOP00000004109	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDN1	GCG	ENSCPOP00000028977	ENSCPOP00000014570	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...]	0.414
EDNRA	EDN1	ENSCPOP00000004109	ENSCPOP00000028977	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.999
ENSCPOP00000024015	ENSCPOP00000024842	ENSCPOP00000024015	ENSCPOP00000024842	Uncharacterized protein.	Uncharacterized protein.	0.849
ENSCPOP00000024015	MYOM1	ENSCPOP00000024015	ENSCPOP00000024179	Uncharacterized protein.	Myomesin 1.	0.617
ENSCPOP00000024015	PRKACB	ENSCPOP00000024015	ENSCPOP00000026584	Uncharacterized protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.544
ENSCPOP00000024015	Prkaca	ENSCPOP00000024015	ENSCPOP00000032930	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.544
ENSCPOP00000024842	ENSCPOP00000024015	ENSCPOP00000024842	ENSCPOP00000024015	Uncharacterized protein.	Uncharacterized protein.	0.849
ENSCPOP00000024842	MYOM1	ENSCPOP00000024842	ENSCPOP00000024179	Uncharacterized protein.	Myomesin 1.	0.617
ENSCPOP00000024842	PRKACB	ENSCPOP00000024842	ENSCPOP00000026584	Uncharacterized protein.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.544
ENSCPOP00000024842	Prkaca	ENSCPOP00000024842	ENSCPOP00000032930	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.544
ENSCPOP00000029566	H0WBS2_CAVPO	ENSCPOP00000029566	ENSCPOP00000020438	Uncharacterized protein.	Uncharacterized protein.	0.431
EZR	LCP1	ENSCPOP00000032958	ENSCPOP00000001746	Ezrin.	Lymphocyte cytosolic protein 1.	0.531
EZR	PRKACB	ENSCPOP00000032958	ENSCPOP00000026584	Ezrin.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.958
EZR	Prkaca	ENSCPOP00000032958	ENSCPOP00000032930	Ezrin.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.958
GCG	EDN1	ENSCPOP00000014570	ENSCPOP00000028977	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...]	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.414
H0WBS2_CAVPO	ENSCPOP00000029566	ENSCPOP00000020438	ENSCPOP00000029566	Uncharacterized protein.	Uncharacterized protein.	0.431
LCP1	EZR	ENSCPOP00000001746	ENSCPOP00000032958	Lymphocyte cytosolic protein 1.	Ezrin.	0.531
MROH2A	MROH2B	ENSCPOP00000005829	ENSCPOP00000003013	Maestro heat like repeat family member 2A.	Maestro heat like repeat family member 2B.	0.600
MROH2B	MROH2A	ENSCPOP00000003013	ENSCPOP00000005829	Maestro heat like repeat family member 2B.	Maestro heat like repeat family member 2A.	0.600