STRINGSTRING
URI1 URI1 PPP1R12A PPP1R12A OAZ3 OAZ3 PLEK PLEK PPP2R2B PPP2R2B PAWR PAWR TNF TNF GPLD1 GPLD1 PPARGC1B PPARGC1B GNA12 GNA12 RGN RGN BAG4 BAG4 ROCK2 ROCK2 LPIN1 LPIN1 ITGA1 ITGA1 PPP6R2 PPP6R2 CD300A CD300A MTMR9 MTMR9 PPP1R11 PPP1R11 ENSCPOP00000023060 ENSCPOP00000023060 NUAK1 NUAK1 CMYA5 CMYA5 HTT HTT CHP1 CHP1 RCAN1 RCAN1 LOC100712811 LOC100712811 PPP4R4 PPP4R4 Ppp1r14d Ppp1r14d JAK2 JAK2 MAGI2 MAGI2 CHP2 CHP2 ITGA2 ITGA2 CSNK2B CSNK2B IKBKB IKBKB ROCK1 ROCK1 TMEM132B TMEM132B PPP1R36 PPP1R36 PPP6R1 PPP6R1 PPP1R26 PPP1R26 HPN HPN RIPK3 RIPK3 VRK3 VRK3 Bod1 Bod1 TMEM132C TMEM132C PTPA PTPA MEF2C MEF2C Mprip Mprip SEMA4D SEMA4D SMAD3 SMAD3 BMP2 BMP2 ENSCPOP00000029143 ENSCPOP00000029143 PPP1R35 PPP1R35 Ppp1r2 Ppp1r2 TIPRL TIPRL PTPRC PTPRC PPP1R9B PPP1R9B SLC39A10 SLC39A10 HSP90B1 HSP90B1 NPNT NPNT FKBP1B FKBP1B RPL5 RPL5 PPP1R17 PPP1R17 DRD2 DRD2 PPP1R1B PPP1R1B NCKAP1L NCKAP1L TGFB2 TGFB2 PPP6R3 PPP6R3 CDK5RAP3 CDK5RAP3 STYXL1 STYXL1 PDGFRB PDGFRB PPP1R15B PPP1R15B Ahr Ahr MGAT5 MGAT5 LOC101788539 LOC101788539 CRY2 CRY2 TSC1 TSC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
URI1URI1 prefoldin like chaperone. (539 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1069 aa)
OAZ3Ornithine decarboxylase antizyme 3. (225 aa)
PLEKPleckstrin. (350 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
PAWRPro-apoptotic WT1 regulator. (307 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (839 aa)
PPARGC1BPPARG coactivator 1 beta. (1028 aa)
GNA12G protein subunit alpha 12. (315 aa)
RGNRegucalcin. (299 aa)
BAG4BCL2 associated athanogene 4. (456 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1371 aa)
LPIN1Lipin 1. (899 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1168 aa)
PPP6R2Protein phosphatase 6 regulatory subunit 2. (942 aa)
CD300ACD300a molecule. (309 aa)
MTMR9Myotubularin related protein 9. (549 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
ENSCPOP00000023060Uncharacterized protein. (405 aa)
NUAK1NUAK family kinase 1. (572 aa)
CMYA5Cardiomyopathy associated 5. (3757 aa)
HTTHuntingtin. (3133 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
RCAN1Regulator of calcineurin 1. (249 aa)
LOC100712811Uncharacterized protein. (419 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (832 aa)
Ppp1r14dUncharacterized protein. (146 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa)
CHP2Calcineurin like EF-hand protein 2. (196 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (244 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (739 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
TMEM132BTransmembrane protein 132B. (1060 aa)
PPP1R36Protein phosphatase 1 regulatory subunit 36. (406 aa)
PPP6R1Protein phosphatase 6 regulatory subunit 1. (847 aa)
PPP1R26Protein phosphatase 1 regulatory subunit 26. (1240 aa)
HPNHepsin; Belongs to the peptidase S1 family. (433 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (482 aa)
VRK3VRK serine/threonine kinase 3. (402 aa)
Bod1Uncharacterized protein. (184 aa)
TMEM132CTransmembrane protein 132C. (1074 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (323 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
MpripUncharacterized protein. (2243 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (852 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ENSCPOP00000029143Uncharacterized protein. (98 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35. (248 aa)
Ppp1r2Uncharacterized protein. (205 aa)
TIPRLTOR signaling pathway regulator. (272 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1307 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (821 aa)
SLC39A10Solute carrier family 39 member 10. (828 aa)
HSP90B1Heat shock protein 90 beta family member 1. (807 aa)
NPNTNephronectin. (556 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
RPL5Ribosomal_L18_c domain-containing protein. (297 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (155 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (184 aa)
NCKAP1LNCK associated protein 1 like. (1111 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (440 aa)
PPP6R3Protein phosphatase 6 regulatory subunit 3. (872 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (501 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (317 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (702 aa)
AhrUncharacterized protein. (832 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (735 aa)
LOC101788539Uncharacterized protein. (363 aa)
CRY2Cryptochrome circadian regulator 2. (593 aa)
TSC1TSC complex subunit 1. (1166 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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