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SLC32A1 SLC32A1 Atp5mc1 Atp5mc1 ATP6V1D ATP6V1D COX6B2 COX6B2 SLC9C1 SLC9C1 SLC25A5 SLC25A5 SLC45A2 SLC45A2 ATP6V0D2 ATP6V0D2 SLC36A3 SLC36A3 ATP6V1C1 ATP6V1C1 COX4I2 COX4I2 SLC9B2 SLC9B2 ATP6V1B1 ATP6V1B1 SLC2A13 SLC2A13 SLC9A5 SLC9A5 ATP6V0D1 ATP6V0D1 UQCR10 UQCR10 LETM1 LETM1 ATP6V0A1 ATP6V0A1 SLC11A1 SLC11A1 ATP6V1A ATP6V1A ATP5F1A ATP5F1A SLC17A6 SLC17A6 SLC9A6 SLC9A6 ATP5PB ATP5PB COX7A1 COX7A1 SLC36A1 SLC36A1 COX6C COX6C SLC25A12 SLC25A12 SLC45A1 SLC45A1 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 CYTB CYTB Slc45a4 Slc45a4 OTOP1 OTOP1 H0VZD4_CAVPO H0VZD4_CAVPO ATP5F1B ATP5F1B H0W0J8_CAVPO H0W0J8_CAVPO SLC45A3 SLC45A3 H0W3D2_CAVPO H0W3D2_CAVPO UQCRQ UQCRQ CUNH17orf80 CUNH17orf80 CTNS CTNS SLC15A4 SLC15A4 HVCN1 HVCN1 COX4I1 COX4I1 ATP6V1E2 ATP6V1E2 OTOP2 OTOP2 ATP5F1D ATP5F1D Atp6v1e1 Atp6v1e1 Atp5me Atp5me LOC100727437 LOC100727437 COX8A COX8A Atp5f1c Atp5f1c ENSCPOP00000024366 ENSCPOP00000024366 COX6B1 COX6B1 ATP5F1E ATP5F1E ENSCPOP00000025102 ENSCPOP00000025102 ATP6V1F ATP6V1F ATP6V0A4 ATP6V0A4 COX7A2L COX7A2L ENSCPOP00000026189 ENSCPOP00000026189 ATP6V0C ATP6V0C ENSCPOP00000026600 ENSCPOP00000026600 UQCRFS1 UQCRFS1 ATP6V1G1 ATP6V1G1 SLC9A8 SLC9A8 ATP5MC3 ATP5MC3 SLC25A13 SLC25A13 Atp6v0e2 Atp6v0e2 SLC9A4 SLC9A4 LOC100714158 LOC100714158 ATP6V0E1 ATP6V0E1 SLC9A1 SLC9A1 SLC11A2 SLC11A2 ATP4A ATP4A ATP12A ATP12A ATP6V1G2 ATP6V1G2 COX5A COX5A OTOP3 OTOP3 ATP6V1H ATP6V1H ATP6V1G3 ATP6V1G3 ATP5PD ATP5PD TCIRG1 TCIRG1 COX6A1 COX6A1 Atp5mc2 Atp5mc2 ATP6V1C2 ATP6V1C2 MFSD3 MFSD3 Atp5mg Atp5mg COX7B COX7B ATP5PF ATP5PF SLC46A1 SLC46A1 ATP6V1B2 ATP6V1B2 SLC25A22 SLC25A22 SLC25A18 SLC25A18 SURF1 SURF1 SLC15A1 SLC15A1 SLC4A11 SLC4A11 ATP6V0A2 ATP6V0A2 Atp5po Atp5po SLC9A9 SLC9A9 COX6A2 COX6A2 SLC9A7 SLC9A7 SLC33A1 SLC33A1 SLC25A4 SLC25A4 SLC9A3 SLC9A3 SLC17A7 SLC17A7 SLC15A2 SLC15A2 TMCO3 TMCO3 ATP6V0B ATP6V0B SLC9A2 SLC9A2 SLC36A2 SLC36A2 ASIC5 ASIC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC32A1Solute carrier family 32 member 1. (526 aa)
Atp5mc1ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (247 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (71 aa)
SLC9C1Solute carrier family 9 member C1. (1134 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC45A2Solute carrier family 45 member 2. (533 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
SLC36A3Solute carrier family 36 member 3. (426 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (170 aa)
SLC9B2Solute carrier family 9 member B2. (536 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (560 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (799 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (64 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (736 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
SLC11A1Solute carrier family 11 member 1. (541 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
SLC17A6Solute carrier family 17 member 6. (566 aa)
SLC9A6Solute carrier family 9 member A6. (643 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (80 aa)
SLC36A1Solute carrier family 36 member 1. (442 aa)
COX6CCytochrome c oxidase subunit 6C. (75 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (678 aa)
SLC45A1Solute carrier family 45 member 1. (700 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (513 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
Slc45a4Uncharacterized protein. (815 aa)
OTOP1Otopetrin 1. (578 aa)
H0VZD4_CAVPOATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (136 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (487 aa)
H0W0J8_CAVPOUncharacterized protein. (71 aa)
SLC45A3Solute carrier family 45 member 3. (521 aa)
H0W3D2_CAVPOATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (122 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
CUNH17orf80Uncharacterized protein. (118 aa)
CTNSCystinosin, lysosomal cystine transporter. (319 aa)
SLC15A4Solute carrier family 15 member 4. (577 aa)
HVCN1Hydrogen voltage gated channel 1. (283 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
ATP6V1E2ATPase H+ transporting V1 subunit E2. (226 aa)
OTOP2Otopetrin 2. (560 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
Atp6v1e1Uncharacterized protein. (226 aa)
Atp5meUncharacterized protein. (71 aa)
LOC100727437Uncharacterized protein. (782 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
Atp5f1cATP synthase subunit gamma. (298 aa)
ENSCPOP00000024366Uncharacterized protein. (49 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
ENSCPOP00000025102Uncharacterized protein. (271 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
ENSCPOP00000026189Uncharacterized protein. (201 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
ENSCPOP00000026600Uncharacterized protein. (81 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (115 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (576 aa)
ATP5MC3Mitochondrial ATP synthase lipid-binding protein isoform A; Belongs to the ATPase C chain family. (141 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (678 aa)
Atp6v0e2V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (726 aa)
LOC100714158Uncharacterized protein. (70 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
SLC11A2Solute carrier family 11 member 2. (568 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
ATP12APotassium-transporting ATPase alpha chain 2; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues. (1072 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
COX5ACytochrome c oxidase subunit 5A. (150 aa)
OTOP3Otopetrin 3. (580 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
COX6A1Cytochrome c oxidase subunit 6A, mitochondrial. (111 aa)
Atp5mc2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa)
MFSD3Major facilitator superfamily domain containing 3. (408 aa)
Atp5mgATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
COX7BCytochrome c oxidase subunit 7B. (80 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
SLC25A18Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (302 aa)
SLC15A1Solute carrier family 15 member 1. (708 aa)
SLC4A11Solute carrier family 4 member 11. (881 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
Atp5poUncharacterized protein. (219 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (644 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (96 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (727 aa)
SLC33A1Solute carrier family 33 member 1. (550 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (832 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
SLC15A2Solute carrier family 15 member 2. (690 aa)
TMCO3Transmembrane and coiled-coil domains 3. (694 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (724 aa)
SLC36A2Solute carrier family 36 member 2. (483 aa)
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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