STRINGSTRING
ASIC5 ASIC5 ASIC4 ASIC4 Scnn1g Scnn1g TPCN2 TPCN2 TPCN1 TPCN1 ASIC1 ASIC1 ASIC2 ASIC2 SCNN1A SCNN1A LOC100714922 LOC100714922 Scnn1b Scnn1b ASIC3 ASIC3 Scnn1d Scnn1d
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASIC5Acid sensing ion channel subunit family member 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
ASIC4Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (539 aa)
Scnn1gUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (653 aa)
TPCN2Two pore channel 2. (752 aa)
TPCN1Two pore channel 1. (817 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (493 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and eccrine sweat glands. Also plays a role in taste perception. Belongs to the amilori [...] (680 aa)
LOC100714922Ion_trans domain-containing protein. (685 aa)
Scnn1bUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (532 aa)
Scnn1dUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (618 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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