STRINGSTRING
PFKFB2 PFKFB2 STBD1 STBD1 H0WDE6_CAVPO H0WDE6_CAVPO PYGB PYGB NAGA NAGA PFKL PFKL PHKG2 PHKG2 TKTL2 TKTL2 ALDOC ALDOC ADRB1 ADRB1 PRKAG3 PRKAG3 RB1CC1 RB1CC1 PGD PGD ENOSF1 ENOSF1 ENPP1 ENPP1 NEU1 NEU1 MIOX MIOX FOXK1 FOXK1 PGM2 PGM2 G6PC G6PC ENO3 ENO3 GALK1 GALK1 ALDOB ALDOB TPI1 TPI1 TKTL1 TKTL1 MGAM MGAM PKLR PKLR DHDH DHDH ENO4 ENO4 KHK KHK MAN2C1 MAN2C1 GAPDHS GAPDHS HK3 HK3 TKFC TKFC NEU2 NEU2 HK2 HK2 PKM PKM GPI GPI PFKM PFKM DHTKD1 DHTKD1 LRP5 LRP5 Aldoa Aldoa NEU4 NEU4 GABARAPL1 GABARAPL1 PGAM2 PGAM2 GALM GALM NEU3 NEU3 HEXB HEXB PYGL PYGL GAA GAA HK1 HK1 SI SI ENO2 ENO2 Bad Bad ABHD10 ABHD10 TREH TREH GK5 GK5 GUSB GUSB GLB1 GLB1 OGDH OGDH SORD SORD PFKP PFKP RBKS RBKS DERA DERA BPGM BPGM H0UTL3_CAVPO H0UTL3_CAVPO GPD2 GPD2 NUDT5 NUDT5 PYGM PYGM HTR2A HTR2A Gapdh Gapdh MPPED1 MPPED1 TP53 TP53 G6PC2 G6PC2 GCK GCK GALT GALT PGK1 PGK1 PGAM1 PGAM1 AGL AGL HKDC1 HKDC1 CTBS CTBS FOXK2 FOXK2 MPPED2 MPPED2 LDHA LDHA GM2A GM2A Gk Gk ENO1 ENO1 ENSCPOP00000022694 ENSCPOP00000022694 GALE GALE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (556 aa)
STBD1Starch binding domain 1. (282 aa)
H0WDE6_CAVPOUncharacterized protein. (251 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
NAGAAlpha-galactosidase. (413 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
PHKG2Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
TKTL2Transketolase like 2. (627 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ADRB1G_PROTEIN_RECEP_F1_2 domain-containing protein. (470 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (465 aa)
RB1CC1RB1 inducible coiled-coil 1. (1431 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (303 aa)
ENOSF1Enolase superfamily member 1. (443 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (900 aa)
NEU1Neuraminidase 1. (404 aa)
MIOXMyo-inositol oxygenase. (285 aa)
FOXK1Forkhead box K1. (638 aa)
PGM2Phosphoglucomutase 2. (614 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
ENO3Enolase 3. (434 aa)
GALK1Galactokinase 1. (392 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
TPI1Triosephosphate isomerase. (249 aa)
TKTL1Transketolase like 1. (597 aa)
MGAMMaltase-glucoamylase. (1865 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
DHDHDihydrodiol dehydrogenase. (332 aa)
ENO4Enolase 4. (615 aa)
KHKKetohexokinase. (343 aa)
MAN2C1Mannosidase alpha class 2C member 1. (1032 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (399 aa)
HK3Hexokinase 3. (864 aa)
TKFCTriokinase and FMN cyclase. (578 aa)
NEU2Neuraminidase 2. (381 aa)
HK2Hexokinase 2. (917 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (920 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1600 aa)
AldoaFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
NEU4Neuraminidase 4. (457 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1; Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity); Belongs to the ATG8 family. (117 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (342 aa)
NEU3Neuraminidase 3. (415 aa)
HEXBHexosaminidase subunit beta. (442 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (867 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (952 aa)
HK1Hexokinase 1. (919 aa)
SISucrase-isomaltase. (1831 aa)
ENO2Enolase 2. (434 aa)
BadUncharacterized protein. (166 aa)
ABHD10Abhydrolase domain containing 10. (302 aa)
TREHTrehalase. (580 aa)
GK5Glycerol kinase 5; Belongs to the FGGY kinase family. (524 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (651 aa)
GLB1Galactosidase beta 1; Belongs to the glycosyl hydrolase 35 family. (588 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
SORDSorbitol dehydrogenase. (357 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (792 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (324 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
H0UTL3_CAVPOLipase_GDSL domain-containing protein. (262 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (744 aa)
NUDT5Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (219 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
HTR2A5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...] (470 aa)
GapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (353 aa)
MPPED1Metallophosphoesterase domain containing 1. (326 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (423 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
GCKPhosphotransferase. (414 aa)
GALTGalactose-1-phosphate uridylyltransferase. (379 aa)
PGK1Phosphoglycerate kinase. (417 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1564 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
CTBSChitobiase; Belongs to the glycosyl hydrolase 18 family. (379 aa)
FOXK2Forkhead box K2. (614 aa)
MPPED2Metallophosphoesterase domain containing 2. (294 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
GM2AGM2 ganglioside activator. (166 aa)
GkUncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
ENO1Alpha-enolase. (434 aa)
ENSCPOP00000022694Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (305 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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