47 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPAP2	RNA polymerase II associated protein 2. (574 aa)
	INTS8	Integrator complex subunit 8. (996 aa)
	EXOSC10	Exosome component 10. (901 aa)
	LOC100728313	RNase_PH domain-containing protein. (256 aa)
	EXOSC2	Exosome component 2. (293 aa)
	Rbm7	RRM domain-containing protein. (241 aa)
	EXOSC5	Exosome component 5. (240 aa)
	TOE1	Target of EGR1, exonuclease. (509 aa)
	ENSCPOP00000024633	INT_SG_DDX_CT_C domain-containing protein. (55 aa)
	EXOSC9	Exosome component 9. (439 aa)
	ELL2	Elongation factor for RNA polymerase II 2. (642 aa)
	Exosc6	RNase_PH domain-containing protein. (246 aa)
	INTS12	Integrator complex subunit 12. (462 aa)
	ENSCPOP00000023576	Uncharacterized protein. (201 aa)
	NOP10	NOP10 ribonucleoprotein. (64 aa)
	METTL16	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (552 aa)
	EXOSC4	Exosome component 4. (245 aa)
	MEPCE	Methylphosphate capping enzyme. (678 aa)
	ELL	Elongation factor for RNA polymerase II. (593 aa)
	INTS7	Integrator complex subunit 7. (962 aa)
	USB1	U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (266 aa)
	Tut1	RRM domain-containing protein. (852 aa)
	INTS6L	Integrator complex subunit 6 like. (853 aa)
	INTS9	Integrator complex subunit 9. (659 aa)
	ZCCHC7	Zinc finger CCHC-type containing 7. (564 aa)
	INTS4	Integrator complex subunit 4. (964 aa)
	LARP7	La ribonucleoprotein domain family member 7. (567 aa)
	INTS10	Integrator complex subunit 10. (735 aa)
	INTS2	Integrator complex subunit 2. (1198 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1049 aa)
	INTS3	Integrator complex subunit 3. (1007 aa)
	DKC1	Dyskerin pseudouridine synthase 1. (513 aa)
	SNAPC3	Small nuclear RNA activating complex polypeptide 3. (412 aa)
	EXOSC7	Exosome component 7. (291 aa)
	EXOSC3	Exosome component 3. (275 aa)
	INTS11	Integrator complex subunit 11. (611 aa)
	ELL3	Elongation factor for RNA polymerase II 3. (352 aa)
	ZC3H8	Zinc finger CCCH-type containing 8. (280 aa)
	SNAPC1	Small nuclear RNA activating complex polypeptide 1. (369 aa)
	ICE2	Interactor of little elongation complex ELL subunit 2. (971 aa)
	SNAPC4	Small nuclear RNA activating complex polypeptide 4. (1340 aa)
	METTL4	Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa)
	EXOSC8	Exosome component 8. (276 aa)
	INTS5	Integrator complex subunit 5. (1008 aa)
	INTS1	Integrator complex subunit 1. (2212 aa)
	INTS14	Integrator complex subunit 14. (518 aa)
	INTS6	Integrator complex subunit 6. (717 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKC1	EXOSC10	ENSCPOP00000007923	ENSCPOP00000031644	Dyskerin pseudouridine synthase 1.	Exosome component 10.	0.439
DKC1	NOP10	ENSCPOP00000007923	ENSCPOP00000023399	Dyskerin pseudouridine synthase 1.	NOP10 ribonucleoprotein.	0.999
ELL	ELL2	ENSCPOP00000014559	ENSCPOP00000024394	Elongation factor for RNA polymerase II.	Elongation factor for RNA polymerase II 2.	0.805
ELL	ELL3	ENSCPOP00000014559	ENSCPOP00000007368	Elongation factor for RNA polymerase II.	Elongation factor for RNA polymerase II 3.	0.945
ELL	ENSCPOP00000023576	ENSCPOP00000014559	ENSCPOP00000023576	Elongation factor for RNA polymerase II.	Uncharacterized protein.	0.815
ELL	ICE2	ENSCPOP00000014559	ENSCPOP00000007628	Elongation factor for RNA polymerase II.	Interactor of little elongation complex ELL subunit 2.	0.877
ELL	INTS11	ENSCPOP00000014559	ENSCPOP00000004634	Elongation factor for RNA polymerase II.	Integrator complex subunit 11.	0.595
ELL	INTS12	ENSCPOP00000014559	ENSCPOP00000023810	Elongation factor for RNA polymerase II.	Integrator complex subunit 12.	0.600
ELL	INTS14	ENSCPOP00000014559	ENSCPOP00000000682	Elongation factor for RNA polymerase II.	Integrator complex subunit 14.	0.505
ELL	INTS3	ENSCPOP00000014559	ENSCPOP00000008484	Elongation factor for RNA polymerase II.	Integrator complex subunit 3.	0.593
ELL	INTS4	ENSCPOP00000014559	ENSCPOP00000011217	Elongation factor for RNA polymerase II.	Integrator complex subunit 4.	0.594
ELL	INTS7	ENSCPOP00000014559	ENSCPOP00000013482	Elongation factor for RNA polymerase II.	Integrator complex subunit 7.	0.594
ELL	LARP7	ENSCPOP00000014559	ENSCPOP00000010641	Elongation factor for RNA polymerase II.	La ribonucleoprotein domain family member 7.	0.401
ELL	RPAP2	ENSCPOP00000014559	ENSCPOP00000006460	Elongation factor for RNA polymerase II.	RNA polymerase II associated protein 2.	0.588
ELL	USPL1	ENSCPOP00000014559	ENSCPOP00000008916	Elongation factor for RNA polymerase II.	Ubiquitin specific peptidase like 1.	0.456
ELL	ZC3H8	ENSCPOP00000014559	ENSCPOP00000007424	Elongation factor for RNA polymerase II.	Zinc finger CCCH-type containing 8.	0.811
ELL2	ELL	ENSCPOP00000024394	ENSCPOP00000014559	Elongation factor for RNA polymerase II 2.	Elongation factor for RNA polymerase II.	0.805
ELL2	ELL3	ENSCPOP00000024394	ENSCPOP00000007368	Elongation factor for RNA polymerase II 2.	Elongation factor for RNA polymerase II 3.	0.786
ELL2	ENSCPOP00000023576	ENSCPOP00000024394	ENSCPOP00000023576	Elongation factor for RNA polymerase II 2.	Uncharacterized protein.	0.765
ELL2	ICE2	ENSCPOP00000024394	ENSCPOP00000007628	Elongation factor for RNA polymerase II 2.	Interactor of little elongation complex ELL subunit 2.	0.865