STRINGSTRING
PARK7 PARK7 PCK1 PCK1 HMBS HMBS GUCY2F GUCY2F HMGCLL1 HMGCLL1 NEIL2 NEIL2 TTC38 TTC38 HADHA HADHA CDYL CDYL ENO2 ENO2 ADCY3 ADCY3 GADL1 GADL1 CLYBL CLYBL CYP1B1 CYP1B1 PTGIS PTGIS ENSCPOP00000028454 ENSCPOP00000028454 ADSL ADSL SDSL SDSL Rps3 Rps3 CA3 CA3 HTD2 HTD2 CA12 CA12 PCBD2 PCBD2 ENSCPOP00000029431 ENSCPOP00000029431 UROC1 UROC1 PTS PTS CHAC1 CHAC1 GUCD1 GUCD1 ARMC7 ARMC7 ENSCPOP00000031385 ENSCPOP00000031385 L3HYPDH L3HYPDH HMGA1 HMGA1 GLO1 GLO1 ENSCPOP00000031664 ENSCPOP00000031664 HACD2 HACD2 ECHDC2 ECHDC2 ECHDC3 ECHDC3 Thnsl1 Thnsl1 Ddt Ddt LOC100714444 LOC100714444 POLL POLL NEIL1 NEIL1 DDC DDC GLDC GLDC UROS UROS SHMT1 SHMT1 HOGA1 HOGA1 CA5B CA5B DGLUCY DGLUCY POLB POLB ADCY2 ADCY2 ALOX5AP ALOX5AP ADCY7 ADCY7 ADCY6 ADCY6 C10orf62 C10orf62 CA13 CA13 PTGES2 PTGES2 THNSL2 THNSL2 PISD PISD ADCY9 ADCY9 EHHADH EHHADH HACL1 HACL1 XRCC5 XRCC5 CENPV CENPV PCBD1 PCBD1 Echdc1 Echdc1 LOC111753928 LOC111753928 ENO1 ENO1 CD99L2 CD99L2 ACOD1 ACOD1 LOC100723257 LOC100723257 Paics Paics AZIN1 AZIN1 FH FH ACO2 ACO2 AMD1 AMD1 ARMT1 ARMT1 SGPL1 SGPL1 GGACT GGACT CHAC2 CHAC2 ENSCPOP00000021586 ENSCPOP00000021586 CA5A CA5A MGST2 MGST2 HDC HDC UROD UROD CA4 CA4 LOC100717209 LOC100717209 LOC100731358 LOC100731358 Kyat1 Kyat1 H0W827_CAVPO H0W827_CAVPO Asl Asl CA7 CA7 CA8 CA8 SCLY SCLY MVD MVD NAXD NAXD ALDOC ALDOC CYP1A2 CYP1A2 NPR1 NPR1 GATD1 GATD1 Ggct Ggct CA14 CA14 LTC4S LTC4S LOC100720895 LOC100720895 FTCD FTCD Bst1 Bst1 CTH CTH PPCDC PPCDC CYP1A1 CYP1A1 ENOSF1 ENOSF1 CA10 CA10 LOC100735470 LOC100735470 ETNPPL ETNPPL MGST3 MGST3 GUCY1B1 GUCY1B1 SRR SRR CYP17A1 CYP17A1 H0VR40_CAVPO H0VR40_CAVPO ADCY4 ADCY4 USB1 USB1 SDS SDS ADCY5 ADCY5 IREB2 IREB2 HACD4 HACD4 GAD2 GAD2 HACD3 HACD3 FECH FECH ENO3 ENO3 H0VN16_CAVPO H0VN16_CAVPO HAL HAL ALOXE3 ALOXE3 ALOX12B ALOX12B CA1 CA1 SHMT2 SHMT2 CA11 CA11 TSEN34 TSEN34 ALDOB ALDOB TPI1 TPI1 GMDS GMDS ECHS1 ECHS1 MOCOS MOCOS PAM PAM Gatd3a Gatd3a Tyw1 Tyw1 GUCY1A1 GUCY1A1 ENO4 ENO4 PCK2 PCK2 GAD1 GAD1 ADCY10 ADCY10 ACMSD ACMSD ACO1 ACO1 PDXDC1 PDXDC1 XRCC6 XRCC6 NEIL3 NEIL3 NTHL1 NTHL1 APIP APIP ME1 ME1 ADCY1 ADCY1 FASN FASN ECI1 ECI1 TGDS TGDS GGCX GGCX ALKBH1 ALKBH1 GUCY2D GUCY2D DERA DERA MLYCD MLYCD AUH AUH LOC100735737 LOC100735737 NPR2 NPR2 CA9 CA9 GUCY1A2 GUCY1A2 TBXAS1 TBXAS1 TKFC TKFC HSD17B4 HSD17B4 KYAT3 KYAT3 H0VE82_CAVPO H0VE82_CAVPO HACD1 HACD1 OGG1 OGG1 HMGCL HMGCL GOT1 GOT1 GUCY2C GUCY2C ODC1 ODC1 UXS1 UXS1 MOCS1 MOCS1 APMAP APMAP RSAD2 RSAD2 UMPS UMPS Tsen2 Tsen2 CA2 CA2 Rnaset2 Rnaset2 Cbs Cbs CYP2S1 CYP2S1 Aldoa Aldoa ALAD ALAD LOC100732696 LOC100732696 ADCY8 ADCY8 CSAD CSAD NPL NPL
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
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gene neighborhood
gene fusions
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PARK7Parkinsonism associated deglycase. (189 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
HMBSHydroxymethylbilane synthase. (361 aa)
GUCY2FGuanylate cyclase. (1109 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. (307 aa)
NEIL2Nei like DNA glycosylase 2. (336 aa)
TTC38Tetratricopeptide repeat domain 38. (468 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
CDYLChromodomain Y like. (571 aa)
ENO2Enolase 2. (434 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GADL1Glutamate decarboxylase like 1. (503 aa)
CLYBLCitrate lyase beta like. (343 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (475 aa)
ENSCPOP00000028454Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (259 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (484 aa)
SDSLSerine dehydratase like. (330 aa)
Rps3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
CA3Carbonic anhydrase 3; Belongs to the alpha-carbonic anhydrase family. (260 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (158 aa)
CA12Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family. (356 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (102 aa)
ENSCPOP00000029431Uncharacterized protein. (111 aa)
UROC1Urocanate hydratase 1. (701 aa)
PTS6-pyruvoyl tetrahydrobiopterin synthase. (145 aa)
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa)
GUCD1Guanylyl cyclase domain containing 1. (239 aa)
ARMC7Armadillo repeat containing 7. (198 aa)
ENSCPOP00000031385annotation not available (138 aa)
L3HYPDHTrans-L-3-hydroxyproline dehydratase. (354 aa)
HMGA1High mobility group AT-hook 1. (108 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
ENSCPOP00000031664Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (702 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (202 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
ECHDC3Enoyl-CoA hydratase domain containing 3. (300 aa)
Thnsl1Uncharacterized protein. (226 aa)
DdtUncharacterized protein. (118 aa)
LOC100714444Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (271 aa)
POLLDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (594 aa)
NEIL1Nei like DNA glycosylase 1. (401 aa)
DDCAromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. (480 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1005 aa)
UROSUroporphyrinogen III synthase. (265 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (321 aa)
CA5BCarbonic anhydrase 5B; Belongs to the alpha-carbonic anhydrase family. (316 aa)
DGLUCYD-glutamate cyclase. (554 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
C10orf62Chromosome 10 open reading frame 62. (255 aa)
CA13Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. (262 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (370 aa)
THNSL2Threonine synthase like 2. (484 aa)
PISDPhosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (416 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
EHHADHEnoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
XRCC5X-ray repair cross complementing 5. (739 aa)
CENPVCentromere protein V. (166 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa)
Echdc1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (301 aa)
LOC111753928Uncharacterized protein. (139 aa)
ENO1Alpha-enolase. (434 aa)
CD99L2CD99 molecule like 2. (208 aa)
ACOD1Aconitate decarboxylase 1. (470 aa)
LOC100723257Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
PaicsAIRC domain-containing protein. (425 aa)
AZIN1Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (447 aa)
FHFumarate hydratase. (508 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
ARMT1Acidic residue methyltransferase 1. (441 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
GGACTGamma-glutamylamine cyclotransferase. (150 aa)
CHAC2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (178 aa)
ENSCPOP00000021586AIRC domain-containing protein. (382 aa)
CA5ACarbonic anhydrase 5A; Belongs to the alpha-carbonic anhydrase family. (291 aa)
MGST2Microsomal glutathione S-transferase 2. (147 aa)
HDCHistidine decarboxylase. (642 aa)
URODUroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (367 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (306 aa)
LOC100717209Ribonuclease pancreatic B; Belongs to the pancreatic ribonuclease family. (154 aa)
LOC100731358Beta_elim_lyase domain-containing protein. (392 aa)
Kyat1Aminotran_1_2 domain-containing protein. (424 aa)
H0W827_CAVPOUncharacterized protein. (103 aa)
AslUncharacterized protein. (465 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (261 aa)
CA8Carbonic anhydrase 8; Belongs to the alpha-carbonic anhydrase family. (255 aa)
SCLYSelenocysteine lyase. (433 aa)
MVDDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
NAXDATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (329 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
CYP1A2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (515 aa)
NPR1Guanylate cyclase. (881 aa)
GATD1Glutamine amidotransferase like class 1 domain containing 1. (220 aa)
GgctUncharacterized protein. (190 aa)
CA14Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family. (337 aa)
LTC4SLeukotriene C4 synthase; Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4; Belongs to the MAPEG family. (102 aa)
LOC100720895Ribonuclease A C1; Belongs to the pancreatic ribonuclease family. (152 aa)
FTCDFormimidoyltransferase cyclodeaminase. (540 aa)
Bst1Uncharacterized protein. (288 aa)
CTHCystathionine gamma-lyase. (399 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (204 aa)
CYP1A1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (516 aa)
ENOSF1Enolase superfamily member 1. (443 aa)
CA10Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family. (328 aa)
LOC100735470Uncharacterized protein. (296 aa)
ETNPPLEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
MGST3Microsomal glutathione S-transferase 3. (156 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (622 aa)
SRRSerine racemase. (322 aa)
CYP17A1Steroid 17-alpha-hydroxylase/17,20 lyase; A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, [...] (499 aa)
H0VR40_CAVPOCytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (252 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate; Belongs to the 2H phosphoesterase superfamily. USB1 family. (266 aa)
SDSSerine dehydratase. (327 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1032 aa)
IREB2Iron responsive element binding protein 2. (839 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (231 aa)
GAD2Glutamate decarboxylase 2. (585 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa)
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (424 aa)
ENO3Enolase 3. (434 aa)
H0VN16_CAVPOUncharacterized protein. (71 aa)
HALHistidine ammonia-lyase; Belongs to the PAL/histidase family. (657 aa)
ALOXE3Arachidonate lipoxygenase 3. (711 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (700 aa)
CA1Carbonic anhydrase 1; Belongs to the alpha-carbonic anhydrase family. (259 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
CA11Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family. (323 aa)
TSEN34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (311 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
TPI1Triosephosphate isomerase. (249 aa)
GMDSGDP-mannose 4,6-dehydratase. (349 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (873 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (975 aa)
Gatd3aUncharacterized protein. (273 aa)
Tyw1Flavodoxin-like domain-containing protein. (739 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
ENO4Enolase 4. (615 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (652 aa)
GAD1Glutamate decarboxylase 1. (594 aa)
ADCY10Adenylate cyclase 10. (1581 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
PDXDC1Pyridoxal dependent decarboxylase domain containing 1. (786 aa)
XRCC6X-ray repair cross complementing 6. (609 aa)
NEIL3Nei like DNA glycosylase 3. (607 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (260 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
ME1Malic enzyme. (501 aa)
ADCY1Adenylate cyclase 1. (944 aa)
FASNFatty acid synthase. (2530 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
TGDSTDP-glucose 4,6-dehydratase. (355 aa)
GGCXGamma-glutamyl carboxylase. (754 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
GUCY2DGuanylate cyclase. (1102 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
LOC100735737Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (209 aa)
NPR2Guanylate cyclase. (1047 aa)
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (431 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (635 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (533 aa)
TKFCTriokinase and FMN cyclase. (578 aa)
HSD17B4Uncharacterized protein. (713 aa)
KYAT3Kynurenine aminotransferase 3. (451 aa)
H0VE82_CAVPOCytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (243 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (249 aa)
OGG18-oxoguanine DNA glycosylase. (303 aa)
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (325 aa)
GOT1Aspartate aminotransferase. (413 aa)
GUCY2CHeat-stable enterotoxin receptor; Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1079 aa)
ODC1Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (461 aa)
UXS1UDP-glucuronate decarboxylase 1. (420 aa)
MOCS1Molybdenum cofactor synthesis 1. (636 aa)
APMAPAdipocyte plasma membrane associated protein. (415 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (358 aa)
UMPSUridine monophosphate synthetase. (480 aa)
Tsen2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (448 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (249 aa)
Rnaset2Uncharacterized protein; Belongs to the RNase T2 family. (253 aa)
CbsCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (538 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1. (503 aa)
AldoaFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
LOC100732696Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CSADCysteine sulfinic acid decarboxylase. (493 aa)
NPLN-acetylneuraminate pyruvate lyase; Belongs to the DapA family. (320 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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