STRINGSTRING
RAD51 RAD51 CHTF18 CHTF18 RFC4 RFC4 RFC2 RFC2 WRNIP1 WRNIP1 HELB HELB MAML1 MAML1 DHX9 DHX9 RFC5 RFC5 DNA2 DNA2 PIF1 PIF1 HELQ HELQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
CHTF18Chromosome transmission fidelity factor 18. (988 aa)
RFC4Replication factor C subunit 4. (363 aa)
RFC2Replication factor C subunit 2. (352 aa)
WRNIP1WRN helicase interacting protein 1. (568 aa)
HELBDNA helicase B. (1063 aa)
MAML1Mastermind like transcriptional coactivator 1. (794 aa)
DHX9DExH-box helicase 9. (1373 aa)
RFC5Replication factor C subunit 5. (340 aa)
DNA2DNA replication helicase/nuclease 2. (1021 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (463 aa)
HELQHelicase, POLQ like. (1054 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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