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| | LOC100717552 | C-C motif chemokine. (120 aa) |
| | LXN | Latexin. (222 aa) |
| | UCHL1 | Ubiquitin carboxyl-terminal hydrolase. (182 aa) |
| | EPHB1 | EPH receptor B1. (736 aa) |
| | RETREG1 | Reticulophagy regulator 1. (413 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (307 aa) |
| | SCN1A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1997 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (189 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (798 aa) |
| | CACNB3 | Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa) |
| | CNR2 | Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (355 aa) |
| | MMP24 | Matrix metallopeptidase 24. (573 aa) |
| | P2rx4 | Uncharacterized protein. (343 aa) |
| | CACNA1B | Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2270 aa) |
| | KCNA1 | Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | HOXD1 | Homeobox D1. (312 aa) |
| | PRDM12 | PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (329 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1381 aa) |
| | TMEM120A | Transmembrane protein 120A. (343 aa) |
| | OPRK1 | Kappa-type opioid receptor; G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by r [...] (386 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (553 aa) |
| | MME | Membrane metalloendopeptidase. (718 aa) |
| | NMU | Neuromedin-U-9. (171 aa) |
| | IAPP | Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. (92 aa) |
| | SCN3A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1975 aa) |
| | TRPV1 | Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits [...] (839 aa) |
| | CHRNA4 | Cholinergic receptor nicotinic alpha 4 subunit. (620 aa) |
| | Ccr2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | TAC1 | Substance P. (129 aa) |
| | Aqp1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | Trpa1 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (991 aa) |
| | KCND2 | Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (2337 aa) |
| | CHRNA5 | Cholinergic receptor nicotinic alpha 5 subunit. (438 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (711 aa) |
| | SCN9A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (325 aa) |
| | LOC100730761 | Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (120 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1462 aa) |
| | GRM3 | Glutamate metabotropic receptor 3. (877 aa) |
| | NPVF | Neuropeptide VF precursor. (190 aa) |
| | SCN10A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa) |
| | CACNA1E | Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2313 aa) |
| | KCNIP3 | Potassium voltage-gated channel interacting protein 3. (256 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (180 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (837 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1156 aa) |
| | OPRM1 | Mu-type opioid receptor; Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP- bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell ty [...] (416 aa) |
| | ADRB1 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (470 aa) |
| | GIP | Gastric inhibitory polypeptide. (145 aa) |
| | NIPSNAP1 | Nipsnap homolog 1. (286 aa) |
| | KCNK4 | Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (392 aa) |
| | CACNA1A | Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2105 aa) |
| | H0WA79_CAVPO | ANF_receptor domain-containing protein. (187 aa) |
| | CNR1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa) |
| | NLGN2 | Neuroligin 2. (662 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | ASIC3 | Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (532 aa) |
| | PHF24 | PHD finger protein 24. (400 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | OPRL1 | Nociceptin receptor; G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociceptio [...] (370 aa) |
| | PTGES | Prostaglandin E synthase. (153 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (215 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | POMK | Protein O-mannose kinase. (350 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (943 aa) |
| | LOC106027640 | C-C motif chemokine. (97 aa) |
| | P2RY2 | Purinergic receptor P2Y2; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | PENK | Met-enkephalin-Arg-Gly-Leu; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(238-259) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. (268 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (346 aa) |
| | Tac4 | Uncharacterized protein. (90 aa) |
| | ANO1 | Anoctamin. (1011 aa) |
| | MC1R | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (316 aa) |
| | KCNA2 | Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa) |
| | CRHR2 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa) |
| | PTGES3 | Prostaglandin E synthase 3. (160 aa) |
| | ENSCPOP00000029877 | PDZ domain-containing protein. (147 aa) |
| | EPHX2 | Epoxide hydrolase 2. (469 aa) |
| | Chrnb2 | Uncharacterized protein. (499 aa) |
| | ENSCPOP00000030659 | G_PROTEIN_RECEP_F3_4 domain-containing protein. (497 aa) |
| | IL1RN | Interleukin-1. (176 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | ENSCPOP00000032677 | Eph LBD domain-containing protein. (286 aa) |
| | ARRB2 | Arrestin beta 2. (417 aa) |
| | NPY1R | Neuropeptide Y receptor type 1; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
