STRINGSTRING
EIF2A EIF2A RPS21 RPS21 RPS8 RPS8 RPS12 RPS12 UBA52 UBA52 RPS13 RPS13 Rps29 Rps29 Rps16 Rps16 Rps20 Rps20 ENSCPOP00000026921 ENSCPOP00000026921 ENSCPOP00000027464 ENSCPOP00000027464 Rps3 Rps3 RPSA RPSA EIF2D EIF2D RPS7 RPS7 RPS25 RPS25 LOC100731991 LOC100731991 MRPS11 MRPS11 RPS11 RPS11 RPS3A RPS3A H0VV17_CAVPO H0VV17_CAVPO Rps27 Rps27 H0VVA1_CAVPO H0VVA1_CAVPO H0VW46_CAVPO H0VW46_CAVPO H0VXS6_CAVPO H0VXS6_CAVPO RPS27L RPS27L LOC100716847 LOC100716847 H0W0Y6_CAVPO H0W0Y6_CAVPO ISG15 ISG15 RPS9 RPS9 H0W359_CAVPO H0W359_CAVPO RPS28 RPS28 RPS14 RPS14 H0W5N6_CAVPO H0W5N6_CAVPO H0W740_CAVPO H0W740_CAVPO H0WAD6_CAVPO H0WAD6_CAVPO RPS5 RPS5 H0WCY6_CAVPO H0WCY6_CAVPO Rps26 Rps26 H0WDT2_CAVPO H0WDT2_CAVPO RPS15A RPS15A DHX29 DHX29 RPS23 RPS23 Rps2 Rps2 ENSCPOP00000029397 ENSCPOP00000029397 RPS19 RPS19 ENSCPOP00000029431 ENSCPOP00000029431 ENSCPOP00000029461 ENSCPOP00000029461 ENSCPOP00000031008 ENSCPOP00000031008 ENSCPOP00000031523 ENSCPOP00000031523 ENSCPOP00000031613 ENSCPOP00000031613 ENSCPOP00000031632 ENSCPOP00000031632 ENSCPOP00000031834 ENSCPOP00000031834 ENSCPOP00000032553 ENSCPOP00000032553 RPS10-NUDT3 RPS10-NUDT3 LOC100729272 LOC100729272 ENSCPOP00000024016 ENSCPOP00000024016 RPS4X RPS4X Rps27a Rps27a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (534 aa)
RPS2140S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (86 aa)
RPS840S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
RPS1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
RPS13Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (132 aa)
Rps29Uncharacterized protein. (56 aa)
Rps16Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (146 aa)
Rps20Ribosomal_S10 domain-containing protein. (119 aa)
ENSCPOP00000026921S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (194 aa)
ENSCPOP00000027464Uncharacterized protein. (216 aa)
Rps3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
RPSA40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa)
EIF2DEukaryotic translation initiation factor 2D. (568 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
RPS2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (125 aa)
LOC10073199140S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
MRPS11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (192 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (264 aa)
H0VV17_CAVPOUncharacterized protein. (142 aa)
Rps2740S ribosomal protein S27. (84 aa)
H0VVA1_CAVPOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (211 aa)
H0VW46_CAVPORibosomal_S5_C domain-containing protein. (69 aa)
H0VXS6_CAVPOUncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (124 aa)
RPS27L40S ribosomal protein S27. (105 aa)
LOC100716847Uncharacterized protein. (80 aa)
H0W0Y6_CAVPOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (238 aa)
ISG15ISG15 ubiquitin like modifier. (157 aa)
RPS9Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
H0W359_CAVPO40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (159 aa)
RPS28Ribosomal protein S28. (69 aa)
RPS14Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
H0W5N6_CAVPO40S ribosomal protein S27. (84 aa)
H0W740_CAVPOUncharacterized protein. (126 aa)
H0WAD6_CAVPOUbiquitin-like domain-containing protein. (111 aa)
RPS5Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
H0WCY6_CAVPOS5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (227 aa)
Rps2640S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
H0WDT2_CAVPOUbiquitin-like domain-containing protein. (127 aa)
RPS15ARibosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1334 aa)
RPS23Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
Rps2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
ENSCPOP00000029397Uncharacterized protein. (171 aa)
RPS19Ribosomal protein S19. (176 aa)
ENSCPOP00000029431Uncharacterized protein. (111 aa)
ENSCPOP0000002946140S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (252 aa)
ENSCPOP00000031008Ribosomal_S10 domain-containing protein. (116 aa)
ENSCPOP00000031523Uncharacterized protein. (129 aa)
ENSCPOP00000031613S10_plectin domain-containing protein. (151 aa)
ENSCPOP00000031632Ubiquitin-like domain-containing protein. (141 aa)
ENSCPOP00000031834Uncharacterized protein. (73 aa)
ENSCPOP00000032553Ribosomal_S10 domain-containing protein. (104 aa)
RPS10-NUDT3S10_plectin domain-containing protein. (165 aa)
LOC10072927240S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
ENSCPOP0000002401640S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (237 aa)
RPS4X40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
Rps27aUbiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.