STRINGSTRING
C15orf41 C15orf41 ERCC2 ERCC2 IKZF1 IKZF1 ABCB10 ABCB10 HBZ HBZ ZBTB7A ZBTB7A SLC25A40 SLC25A40 NFE2L1 NFE2L1 H0WC94_CAVPO H0WC94_CAVPO DYRK3 DYRK3 G6PD G6PD Rhce Rhce MPIG6B MPIG6B EPO EPO TSPO2 TSPO2 SLC4A1 SLC4A1 ID2 ID2 SRF SRF PLA2G10 PLA2G10 KCNQ1 KCNQ1 SPI1 SPI1 ZFPM1 ZFPM1 ALAS1 ALAS1 SMARCA4 SMARCA4 RHAG RHAG JAK2 JAK2 EPAS1 EPAS1 FECH FECH Etv2 Etv2 SOX6 SOX6 LYN LYN KIT KIT RCOR1 RCOR1 FLVCR1 FLVCR1 MAEA MAEA ADGRF4 ADGRF4 SFXN1 SFXN1 UBA5 UBA5 SLC25A5 SLC25A5 NCKAP1L NCKAP1L RB1 RB1 GATA3 GATA3 GATA1 GATA1 TMEM14C TMEM14C CDK5RAP3 CDK5RAP3 ALAS2 ALAS2 TGFBR3 TGFBR3 PTPN2 PTPN2 UFL1 UFL1 BMP4 BMP4 HCLS1 HCLS1 DMTN DMTN MFHAS1 MFHAS1 TCEA1 TCEA1 SMAD5 SMAD5 ADAR ADAR Lyar Lyar EXOC6 EXOC6 TAL1 TAL1 CITED2 CITED2 ADD1 ADD1 BAP1 BAP1 SP3 SP3 TMOD3 TMOD3 HSPA9 HSPA9 SH2B3 SH2B3 H0UVZ6_CAVPO H0UVZ6_CAVPO NCOR1 NCOR1 DNASE2 DNASE2 BPGM BPGM TRIM10 TRIM10 ATP5IF1 ATP5IF1 LOC100722203 LOC100722203 MB MB ENSCPOP00000030875 ENSCPOP00000030875 NCAPG2 NCAPG2 MED1 MED1 THRA THRA PTBP3 PTBP3 ANK1 ANK1 RHEX RHEX PKNOX1 PKNOX1 BCL6 BCL6 JMJD6 JMJD6 L3MBTL3 L3MBTL3 SLC11A2 SLC11A2 SLC25A38 SLC25A38 JAK3 JAK3 ACIN1 ACIN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C15orf41Chromosome 15 open reading frame 41. (281 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
IKZF1IKAROS family zinc finger 1. (511 aa)
ABCB10ATP binding cassette subfamily B member 10. (711 aa)
HBZHemoglobin subunit zeta; Belongs to the globin family. (142 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (564 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (743 aa)
H0WC94_CAVPOUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (770 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
RhceAmmonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (372 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
TSPO2Translocator protein 2. (171 aa)
SLC4A1Anion exchange protein. (901 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
SRFSerum response factor. (461 aa)
PLA2G10Phospholipase A(2). (152 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (671 aa)
SPI1Spi-1 proto-oncogene. (258 aa)
ZFPM1Zinc finger protein, FOG family member 1. (876 aa)
ALAS15-aminolevulinate synthase. (640 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1636 aa)
RHAGRh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (430 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
EPAS1Endothelial PAS domain protein 1. (833 aa)
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (424 aa)
Etv2ETS domain-containing protein. (153 aa)
SOX6SRY-box transcription factor 6. (859 aa)
LYNTyrosine-protein kinase. (512 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
RCOR1REST corepressor 1. (467 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (552 aa)
MAEAMacrophage erythroblast attacher. (396 aa)
ADGRF4Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (681 aa)
SFXN1Sidoreflexin. (322 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (403 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
NCKAP1LNCK associated protein 1 like. (1111 aa)
RB1RB transcriptional corepressor 1. (840 aa)
GATA3GATA binding protein 3. (443 aa)
GATA1GATA binding protein 1. (401 aa)
TMEM14CTransmembrane protein 14C. (114 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (501 aa)
ALAS25-aminolevulinate synthase. (587 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (364 aa)
UFL1UFM1 specific ligase 1. (762 aa)
BMP4Bone morphogenetic protein 4. (404 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (472 aa)
DMTNDematin actin binding protein. (371 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (952 aa)
TCEA1Transcription elongation factor A1. (305 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ADARAdenosine deaminase RNA specific. (1164 aa)
LyarUncharacterized protein. (191 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (804 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (191 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
ADD1Adducin 1. (733 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
SP3Sp3 transcription factor. (690 aa)
TMOD3Tropomodulin 3. (352 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (678 aa)
SH2B3SH2B adaptor protein 3. (557 aa)
H0UVZ6_CAVPOUncharacterized protein. (438 aa)
NCOR1Nuclear receptor corepressor 1. (2389 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (357 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
TRIM10Tripartite motif containing 10. (371 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (103 aa)
LOC100722203BZIP domain-containing protein. (150 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
ENSCPOP00000030875ARID domain-containing protein. (504 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1168 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa)
THRAThyroid hormone receptor alpha. (514 aa)
PTBP3Polypyrimidine tract binding protein 3. (551 aa)
ANK1Ankyrin 1. (1911 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (171 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
BCL6BCL6 transcription repressor. (705 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (779 aa)
SLC11A2Solute carrier family 11 member 2. (568 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (299 aa)
JAK3Tyrosine-protein kinase. (1078 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1327 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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