STRINGSTRING
SACM1L SACM1L INPP5B INPP5B INPP5F INPP5F H0VER4_CAVPO H0VER4_CAVPO DGKD DGKD INPP5E INPP5E Plpp1 Plpp1 ACADL ACADL DGKA DGKA HSD17B4 HSD17B4 CYP24A1 CYP24A1 ABCD2 ABCD2 ALDH1L2 ALDH1L2 PLPP6 PLPP6 HADH HADH PLPP5 PLPP5 ACADVL ACADVL ALOX15B ALOX15B CYP1A1 CYP1A1 CPT1C CPT1C AGK AGK ACADS ACADS FA2H FA2H ACOX1 ACOX1 INPP5A INPP5A ACAT1 ACAT1 OCRL OCRL MTMR10 MTMR10 SOAT1 SOAT1 ALOX12B ALOX12B MBOAT7 MBOAT7 PLPP4 PLPP4 INPP5J INPP5J ACADSB ACADSB SPHK1 SPHK1 ECHS1 ECHS1 ABCD1 ABCD1 CPT2 CPT2 MTMR7 MTMR7 PPARD PPARD CROT CROT ACADM ACADM TMEM130 TMEM130 MBOAT4 MBOAT4 MBOAT2 MBOAT2 PEX13 PEX13 CYGB CYGB ECHDC2 ECHDC2 MTM1 MTM1 SLC35C1 SLC35C1 ENSCPOP00000031385 ENSCPOP00000031385 ENSCPOP00000031025 ENSCPOP00000031025 HSD17B10 HSD17B10 ST3GAL2 ST3GAL2 SYNJ2 SYNJ2 EPHX2 EPHX2 ETFB ETFB DGKG DGKG DGKQ DGKQ B3GALT1 B3GALT1 INPP5D INPP5D LEP LEP ADH5 ADH5 PORCN PORCN A3GALT2 A3GALT2 CYP4V2 CYP4V2 PLPPR3 PLPPR3 ENSCPOP00000027395 ENSCPOP00000027395 DGKE DGKE ADIPOQ ADIPOQ CPT1A CPT1A STARD4 STARD4 DECR1 DECR1 Acaa1 Acaa1 INPPL1 INPPL1 INPP4B INPP4B SPHK2 SPHK2 EHHADH EHHADH PEX7 PEX7 HACL1 HACL1 LPCAT3 LPCAT3 ENSCPOP00000024929 ENSCPOP00000024929 DGKZ DGKZ GBGT1 GBGT1 CYP2E1 CYP2E1 ILVBL ILVBL Echdc1 Echdc1 PLA2G7 PLA2G7 PIP4P2 PIP4P2 BDH2 BDH2 LOC100723257 LOC100723257 PSORS1C2 PSORS1C2 PEX2 PEX2 MTMR9 MTMR9 MAPK14 MAPK14 PIP4P1 PIP4P1 ENSCPOP00000022046 ENSCPOP00000022046 ENSCPOP00000021806 ENSCPOP00000021806 SYNJ1 SYNJ1 DGKI DGKI SGPP1 SGPP1 GCDH GCDH Plpp3 Plpp3 H0WBQ2_CAVPO H0WBQ2_CAVPO CERK CERK PEX5 PEX5 LOC100733735 LOC100733735 ACAD11 ACAD11 IVD IVD PTEN PTEN LCAT LCAT LOC100719677 LOC100719677 ACOX3 ACOX3 PLPP2 PLPP2 H0W3F4_CAVPO H0W3F4_CAVPO CRAT CRAT LOC100721187 LOC100721187 SESN2 SESN2 GBA2 GBA2 HAO1 HAO1 ADIPOR1 ADIPOR1 AUH AUH MLYCD MLYCD ACAD10 ACAD10 ACAT2 ACAT2 PPARG PPARG ECI1 ECI1 ABCD3 ABCD3 SGPP2 SGPP2 SLC25A17 SLC25A17 PLPPR5 PLPPR5 MTMR3 MTMR3 MTMR12 MTMR12 GLT6D1 GLT6D1 GBA GBA B4GALNT1 B4GALNT1 MTMR4 MTMR4 ALOX12 ALOX12 LOC100717408 LOC100717408 ETFDH ETFDH ACAA2 ACAA2 ABCD4 ABCD4 ECI2 ECI2 HADHB HADHB PRKAA1 PRKAA1 LOC100725517 LOC100725517 SOAT2 SOAT2 PLPPR2 PLPPR2 HADHA HADHA PIK3C2B PIK3C2B ST3GAL4 ST3GAL4 DGKH DGKH ETFA ETFA B4GALNT2 B4GALNT2 PLPPR4 PLPPR4 ACOX2 ACOX2 INPP5K INPP5K MTMR6 MTMR6 LOC100732696 LOC100732696 SLC27A2 SLC27A2 PHYH PHYH CPT1B CPT1B H0VAK6_CAVPO H0VAK6_CAVPO MBOAT1 MBOAT1 MTMR11 MTMR11 MTMR2 MTMR2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (983 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1107 aa)
H0VER4_CAVPODAGKc domain-containing protein. (277 aa)
DGKDDiacylglycerol kinase. (1160 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (646 aa)
Plpp1Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these b [...] (284 aa)
ACADLAcyl-CoA dehydrogenase long chain. (432 aa)
DGKADiacylglycerol kinase. (736 aa)
HSD17B4Uncharacterized protein. (713 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
PLPP6Phospholipid phosphatase 6. (278 aa)
HADHHydroxyacyl-CoA dehydrogenase. (313 aa)
PLPP5Phospholipid phosphatase 5. (244 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (633 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (669 aa)
CYP1A1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (516 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (807 aa)
AGKAcylglycerol kinase. (421 aa)
ACADSAcyl-CoA dehydrogenase short chain. (413 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ACOX1Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (660 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (390 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (900 aa)
MTMR10Myotubularin related protein 10. (753 aa)
SOAT1O-acyltransferase. (543 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (700 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
PLPP4Phospholipid phosphatase 4. (270 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1015 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (424 aa)
SPHK1Sphingosine kinase 1. (386 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
ABCD1ATP binding cassette subfamily D member 1. (723 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa)
MTMR7Myotubularin related protein 7. (640 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (580 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (363 aa)
TMEM130Transmembrane protein 130. (345 aa)
MBOAT4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (333 aa)
MBOAT2Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (537 aa)
PEX13Peroxisomal biogenesis factor 13. (402 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
MTM1Myotubularin 1. (599 aa)
SLC35C1Solute carrier family 35 member C1. (352 aa)
ENSCPOP00000031385annotation not available (138 aa)
ENSCPOP00000031025SAC domain-containing protein. (814 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
SYNJ2Synaptojanin 2. (1489 aa)
EPHX2Epoxide hydrolase 2. (469 aa)
ETFBElectron transfer flavoprotein subunit beta. (255 aa)
DGKGDiacylglycerol kinase. (792 aa)
DGKQDiacylglycerol kinase. (947 aa)
B3GALT1Hexosyltransferase. (326 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1220 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (367 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
A3GALT2Alpha 1,3-galactosyltransferase 2. (337 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (524 aa)
PLPPR3Phospholipid phosphatase related 3. (775 aa)
ENSCPOP00000027395Uncharacterized protein. (56 aa)
DGKEDiacylglycerol kinase. (575 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (247 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
STARD4StAR related lipid transfer domain containing 4. (208 aa)
DECR12,4-dienoyl-CoA reductase 1. (335 aa)
Acaa1Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1267 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
SPHK2Sphingosine kinase 2. (655 aa)
EHHADHEnoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)
PEX7Peroxisomal biogenesis factor 7. (319 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (578 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
DGKZDiacylglycerol kinase. (1118 aa)
GBGT1Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group). (347 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (496 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (634 aa)
Echdc1Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (301 aa)
PLA2G7Platelet-activating factor acetylhydrolase; Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids; Belongs to the AB hydrolase superfamily. Lipase family. (436 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
LOC100723257Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
PSORS1C2Psoriasis susceptibility 1 candidate 2. (138 aa)
PEX2Peroxisomal biogenesis factor 2. (304 aa)
MTMR9Myotubularin related protein 9. (549 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
ENSCPOP00000021806Uncharacterized protein. (312 aa)
SYNJ1Synaptojanin 1. (1607 aa)
DGKIDiacylglycerol kinase. (957 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (407 aa)
GCDHGlutaryl-CoA dehydrogenase. (414 aa)
Plpp3acidPPc domain-containing protein. (312 aa)
H0WBQ2_CAVPOUncharacterized protein. (282 aa)
CERKCeramide kinase. (483 aa)
PEX5Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. (538 aa)
LOC100733735Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (806 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
LCATLecithin-cholesterol acyltransferase. (441 aa)
LOC100719677Uncharacterized protein. (662 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (737 aa)
PLPP2Phospholipid phosphatase 2. (260 aa)
H0W3F4_CAVPOMyotubularin phosphatase domain-containing protein. (121 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
LOC100721187Uncharacterized protein. (489 aa)
SESN2Sestrin 2. (480 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (908 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)
MLYCDMalonyl-CoA decarboxylase. (488 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1059 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (504 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
ABCD3ATP binding cassette subfamily D member 3. (611 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (354 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
PLPPR5Phospholipid phosphatase related 5. (315 aa)
MTMR3Myotubularin related protein 3. (1221 aa)
MTMR12Myotubularin related protein 12. (747 aa)
GLT6D1Glycosyltransferase 6 domain containing 1. (305 aa)
GBAGlucosylceramidase. (516 aa)
B4GALNT1Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa)
MTMR4Myotubularin related protein 4. (1189 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (656 aa)
LOC100717408Adiponectin F1. (333 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
ABCD4ATP binding cassette subfamily D member 4. (602 aa)
ECI2Enoyl-CoA delta isomerase 2. (354 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (487 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
LOC100725517Myotubularin phosphatase domain-containing protein. (355 aa)
SOAT2O-acyltransferase. (457 aa)
PLPPR2Phospholipid phosphatase related 2. (420 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1633 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (441 aa)
DGKHDiacylglycerol kinase. (1144 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
B4GALNT2Beta-1,4-N-acetyl-galactosaminyltransferase 2. (508 aa)
PLPPR4Phospholipid phosphatase related 4. (748 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (461 aa)
MTMR6Myotubularin related protein 6. (620 aa)
LOC100732696Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (718 aa)
SLC27A2Solute carrier family 27 member 2. (619 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (336 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
H0VAK6_CAVPOUncharacterized protein. (177 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (463 aa)
MTMR11Myotubularin related protein 11. (692 aa)
MTMR2Myotubularin related protein 2. (643 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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