STRINGSTRING
ABCA7 ABCA7 Ces1d Ces1d APOM APOM CETP CETP SERAC1 SERAC1 CFTR CFTR STX12 STX12 STARD3 STARD3 ABCA1 ABCA1 LIPG LIPG PIP4K2A PIP4K2A HNF1A HNF1A APOE APOE ABCG4 ABCG4 NPC1 NPC1 ABCA12 ABCA12 OSBP OSBP SOAT2 SOAT2 APOB APOB LIPC LIPC Vps4a Vps4a H0UZN0_CAVPO H0UZN0_CAVPO ARV1 ARV1 CEL CEL TPCN2 TPCN2 NPC2 NPC2 LIMA1 LIMA1 ABCG8 ABCG8 SOAT1 SOAT1 LOC100730472 LOC100730472 SYT7 SYT7 APOA1 APOA1 LDLRAP1 LDLRAP1 LOC100721835 LOC100721835 OSBPL2 OSBPL2 LRP6 LRP6 CAV1 CAV1 STARD4 STARD4 CD36 CD36 ENSCPOP00000024929 ENSCPOP00000024929 ENSCPOP00000024925 ENSCPOP00000024925 TSKU TSKU LOC100717473 LOC100717473 ABCA5 ABCA5 STARD3NL STARD3NL ENSCPOP00000022046 ENSCPOP00000022046 LDLR LDLR APOC1 APOC1 ABCG5 ABCG5 APOC2 APOC2 MSR1 MSR1 LCAT LCAT SCARB1 SCARB1 TSPO2 TSPO2 H0VU94_CAVPO H0VU94_CAVPO STARD5 STARD5 APOA2 APOA2 RELCH RELCH ABCG1 ABCG1 APOF APOF APOA5 APOA5 VPS4B VPS4B PNLIP PNLIP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCA7ATP binding cassette subfamily A member 7. (2108 aa)
Ces1dCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
APOMApolipoprotein M. (192 aa)
CETPCholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (492 aa)
SERAC1Serine active site containing 1. (652 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1448 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (274 aa)
STARD3StAR related lipid transfer domain containing 3. (446 aa)
ABCA1ATP binding cassette subfamily A member 1. (2200 aa)
LIPGLipase G, endothelial type. (498 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (398 aa)
HNF1AHNF1 homeobox A. (628 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (298 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
ABCA12ATP binding cassette subfamily A member 12. (2597 aa)
OSBPOxysterol binding protein. (767 aa)
SOAT2O-acyltransferase. (457 aa)
APOBApolipoprotein B. (4479 aa)
LIPCLipase C, hepatic type. (497 aa)
Vps4aUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
H0UZN0_CAVPOUncharacterized protein. (763 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (259 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (594 aa)
TPCN2Two pore channel 2. (752 aa)
NPC2NPC intracellular cholesterol transporter 2. (150 aa)
LIMA1LIM domain and actin binding 1. (755 aa)
ABCG8ATP binding cassette subfamily G member 8. (658 aa)
SOAT1O-acyltransferase. (543 aa)
LOC100730472Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
SYT7Synaptotagmin 7. (556 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
LOC100721835Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (484 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
STARD4StAR related lipid transfer domain containing 4. (208 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ENSCPOP00000024929SCP2 domain-containing protein. (143 aa)
ENSCPOP00000024925COesterase domain-containing protein. (295 aa)
TSKUTsukushi, small leucine rich proteoglycan. (364 aa)
LOC100717473Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa)
ABCA5ATP binding cassette subfamily A member 5. (1593 aa)
STARD3NLSTARD3 N-terminal like. (235 aa)
ENSCPOP00000022046Thiolase_N domain-containing protein. (103 aa)
LDLRLow density lipoprotein receptor. (807 aa)
APOC1Apolipoprotein C1. (95 aa)
ABCG5ATP binding cassette subfamily G member 5. (480 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. (100 aa)
MSR1Macrophage scavenger receptor 1. (435 aa)
LCATLecithin-cholesterol acyltransferase. (441 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
TSPO2Translocator protein 2. (171 aa)
H0VU94_CAVPOCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (520 aa)
STARD5StAR related lipid transfer domain containing 5. (213 aa)
APOA2Apolipoprotein A2. (101 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1097 aa)
ABCG1ATP binding cassette subfamily G member 1. (666 aa)
APOFApolipoprotein F. (321 aa)
APOA5Apolipoprotein A5. (429 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
PNLIPPancreatic triacylglycerol lipase. (428 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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