STRINGSTRING
MMS19 MMS19 PRMT2 PRMT2 FUS FUS MED1 MED1 HSD17B10 HSD17B10 LOC100731803 LOC100731803 CTNNB1 CTNNB1 PIK3R1 PIK3R1 TRIP4 TRIP4 DCAF1 DCAF1 H0V668_CAVPO H0V668_CAVPO LATS1 LATS1 PPARG PPARG PPARGC1B PPARGC1B PAGR1 PAGR1 PPID PPID NCOR1 NCOR1 NSD1 NSD1 NCOA3 NCOA3 PCNA PCNA PADI2 PADI2 NCOA6 NCOA6 STRN STRN DCAF13 DCAF13 TAF10 TAF10 WBP2 WBP2 CNOT1 CNOT1 WIPI1 WIPI1 Parp1 Parp1 ARID5A ARID5A PSMC3IP PSMC3IP TACC1 TACC1 DNMT1 DNMT1 DDX54 DDX54 SRARP SRARP LCOR LCOR PPARGC1A PPARGC1A NCOA2 NCOA2 ENSCPOP00000022118 ENSCPOP00000022118 NKX3-1 NKX3-1 DNAAF4 DNAAF4 LEF1 LEF1 ZNF366 ZNF366 NCOA1 NCOA1 ENSCPOP00000024428 ENSCPOP00000024428 ARRB1 ARRB1 NRIP1 NRIP1 CCDC62 CCDC62 RNF4 RNF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1027 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (431 aa)
FUSFUS RNA binding protein. (490 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1584 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
LOC100731803Uncharacterized protein. (527 aa)
CTNNB1Catenin beta 1. (781 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TRIP4Thyroid hormone receptor interactor 4. (577 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1451 aa)
H0V668_CAVPOHTH psq-type domain-containing protein. (433 aa)
LATS1Large tumor suppressor kinase 1. (969 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (504 aa)
PPARGC1BPPARG coactivator 1 beta. (1028 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
NCOR1Nuclear receptor corepressor 1. (2389 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2483 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
NCOA6Nuclear receptor coactivator 6. (2064 aa)
STRNStriatin. (780 aa)
DCAF13DDB1 and CUL4 associated factor 13. (445 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (177 aa)
WBP2WW domain binding protein 2. (261 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2294 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
ARID5AAT-rich interaction domain 5A. (511 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (770 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1600 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (879 aa)
SRARPSteroid receptor associated and regulated protein. (163 aa)
LCORLigand dependent nuclear receptor corepressor. (1461 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
NCOA2Nuclear receptor coactivator. (1462 aa)
ENSCPOP00000022118Uncharacterized protein. (565 aa)
NKX3-1NK3 homeobox 1. (224 aa)
DNAAF4Dynein axonemal assembly factor 4. (421 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
ZNF366Zinc finger protein 366. (779 aa)
NCOA1Nuclear receptor coactivator. (1442 aa)
ENSCPOP00000024428PARP-type domain-containing protein. (104 aa)
ARRB1Arrestin beta 1. (430 aa)
NRIP1Nuclear receptor interacting protein 1. (1157 aa)
CCDC62Coiled-coil domain containing 62. (678 aa)
RNF4Ring finger protein 4. (190 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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