STRINGSTRING
LOC100716672 LOC100716672 SFRP2 SFRP2 JUP JUP PIP5KL1 PIP5KL1 IL1RN IL1RN BRAF BRAF Krit1 Krit1 FAM102A FAM102A JAG1 JAG1 APEX1 APEX1 SPRED1 SPRED1 C5orf30 C5orf30 DCN DCN RGCC RGCC WNT4 WNT4 EMILIN2 EMILIN2 CYGB CYGB Rabgef1 Rabgef1 TBXA2R TBXA2R PLXNB3 PLXNB3 Ddt Ddt IL33 IL33 FUZ FUZ MCTP1 MCTP1 APOD APOD SEMA3A SEMA3A CITED2 CITED2 WASL WASL NISCH NISCH PTPRG PTPRG STK26 STK26 MYOCD MYOCD TNF TNF CLDN5 CLDN5 C5 C5 AIF1 AIF1 PPARG PPARG SRGAP3 SRGAP3 STAP1 STAP1 GNA12 GNA12 ACVRL1 ACVRL1 CERS2 CERS2 WDR63 WDR63 SCAI SCAI H0UW27_CAVPO H0UW27_CAVPO CORO1C CORO1C ABCC8 ABCC8 TGFB1 TGFB1 ADAM15 ADAM15 OSBPL8 OSBPL8 PTK2 PTK2 NBL1 NBL1 CALR CALR PTGER4 PTGER4 AGER AGER ADIPOR1 ADIPOR1 ENG ENG ARHGDIB ARHGDIB NRG1 NRG1 TNFAIP6 TNFAIP6 DPYSL3 DPYSL3 RIPOR2 RIPOR2 ADGRB1 ADGRB1 IDH2 IDH2 GPR18 GPR18 CLDN3 CLDN3 EMILIN1 EMILIN1 ACAN ACAN PTN PTN Srgap2 Srgap2 IL24 IL24 CD63 CD63 WNT11 WNT11 ADTRP ADTRP DRD2 DRD2 PADI2 PADI2 H0VFH9_CAVPO H0VFH9_CAVPO ROBO1 ROBO1 VASH1 VASH1 ITGB1BP1 ITGB1BP1 LIMCH1 LIMCH1 CORO1B CORO1B PODN PODN PATZ1 PATZ1 CSNK2B CSNK2B EPHA4 EPHA4 PTPRK PTPRK LRCH1 LRCH1 DLL4 DLL4 PPARD PPARD CDH1 CDH1 GDF2 GDF2 MARVELD3 MARVELD3 NRG3 NRG3 TNN TNN THY1 THY1 APOH APOH FLCN FLCN MECP2 MECP2 DLC1 DLC1 RNF20 RNF20 GNA13 GNA13 MCC MCC TIMP1 TIMP1 DUSP10 DUSP10 MAPK15 MAPK15 IL27RA IL27RA GTPBP4 GTPBP4 CYP19A1 CYP19A1 GSK3B GSK3B PTPRT PTPRT TBX5 TBX5 THBS1 THBS1 NEXMIF NEXMIF MITF MITF MAGI2 MAGI2 NAV3 NAV3 TMEFF2 TMEFF2 GNRH1 GNRH1 NODAL NODAL CARD10 CARD10 BCR BCR SRF SRF H0W027_CAVPO H0W027_CAVPO MEOX2 MEOX2 ADARB1 ADARB1 PODNL1 PODNL1 H0W0Z8_CAVPO H0W0Z8_CAVPO BCL2 BCL2 LOC101788748 LOC101788748 HRG HRG Foxo3 Foxo3 RAP2B RAP2B PTEN PTEN BMPR1A BMPR1A HAS1 HAS1 GSTP1 GSTP1 NKX2-1 NKX2-1 DRD5 DRD5 DPEP1 DPEP1 PTPN23 PTPN23 BMP10 BMP10 Drd4 Drd4 HDAC5 HDAC5 Egfl7 Egfl7 FAM102B FAM102B IGFBP3 IGFBP3 CCN3 CCN3 PPARGC1A PPARGC1A CLDN19 CLDN19 CHRD CHRD APOE APOE TGFBR3 TGFBR3 Ccl25 Ccl25 ACVR1C ACVR1C RECK RECK SEMA6D SEMA6D COL3A1 COL3A1 HNF4A HNF4A ADA ADA NF1 NF1 TIE1 TIE1 PTPRR PTPRR CCL21 CCL21 PDGFB PDGFB FGF2 FGF2 DLG5 DLG5 ADIPOR2 ADIPOR2 HYAL2 HYAL2 LOC100723644 LOC100723644 MEF2C MEF2C RAC1 RAC1 RNF41 RNF41 PHLDB2 PHLDB2 CD300A CD300A TP53INP1 TP53INP1 CXCL12 CXCL12 NOG NOG SLIT2 SLIT2 PLCB1 PLCB1 ATP2B4 ATP2B4 SERPINE1 SERPINE1 ABHD6 ABHD6 ANGPT2 ANGPT2 KANK1 KANK1 STK24 STK24 BMERB1 BMERB1 LOC100722817 LOC100722817 CLIC4 CLIC4 ABHD2 ABHD2 SERPINF1 SERPINF1 MMP28 MMP28 EPHA1 EPHA1 Gcsam Gcsam ATP1B2 ATP1B2 CNN2 CNN2 PTPRJ PTPRJ TRIB1 TRIB1 SLURP1 SLURP1 DRD1 DRD1 LRP1 LRP1 DUSP22 DUSP22 STAT3 STAT3 SRGAP1 SRGAP1 CD74 CD74 SINHCAF SINHCAF PRKG1 PRKG1 SULF1 SULF1 ADGRG1 ADGRG1 AKT1 AKT1 IGFBP5 IGFBP5 SLC9A3R1 SLC9A3R1 ABR ABR DAG1 DAG1 MIIP MIIP LOC100727246 LOC100727246 ZMYND8 ZMYND8 ENSCPOP00000026444 ENSCPOP00000026444 KRT14 KRT14 DUSP1 DUSP1 DACH1 DACH1 EVL EVL DPP4 DPP4 ADIPOQ ADIPOQ SFRP1 SFRP1 CX3CR1 CX3CR1 ENSCPOP00000027386 ENSCPOP00000027386 CAV1 CAV1 RAP2C RAP2C SLAMF8 SLAMF8 NDRG4 NDRG4 NFE2L2 NFE2L2 ADORA3 ADORA3 DAB2IP DAB2IP CX3CL1 CX3CL1 CYP1B1 CYP1B1 AFDN AFDN RRAS RRAS CD200 CD200 STC1 STC1 MAP2K5 MAP2K5 ARID2 ARID2 LOC100735277 LOC100735277 SYNJ2BP SYNJ2BP ADORA1 ADORA1 SVBP SVBP PFN2 PFN2 S1PR2 S1PR2 TCAF1 TCAF1 CLASP1 CLASP1 TAFA5 TAFA5 Clasp2 Clasp2 STARD13 STARD13 PTPRM PTPRM GREM1 GREM1 ENSCPOP00000030875 ENSCPOP00000030875 FAS FAS Dusp3 Dusp3 SHH SHH NEDD9 NEDD9 PTPRU PTPRU PDCD10 PDCD10
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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LOC100716672G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
JUPJunction plakoglobin. (745 aa)
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (423 aa)
IL1RNInterleukin-1. (176 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (738 aa)
Krit1Uncharacterized protein. (736 aa)
FAM102AFamily with sequence similarity 102 member A. (385 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
SPRED1Sprouty related EVH1 domain containing 1. (438 aa)
C5orf30Chromosome 5 open reading frame 30. (207 aa)
DCNDecorin; May affect the rate of fibrils formation. (361 aa)
RGCCRegulator of cell cycle. (133 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
EMILIN2Elastin microfibril interfacer 2. (1042 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
Rabgef1Uncharacterized protein. (491 aa)
TBXA2RThromboxane A2 receptor. (347 aa)
PLXNB3Plexin B3. (1900 aa)
DdtUncharacterized protein. (118 aa)
IL33Interleukin 33. (280 aa)
FUZFuzzy planar cell polarity protein. (392 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (763 aa)
APODApolipoprotein D; APOD occurs in the macromolecular complex with lecithin- transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (189 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
NISCHNischarin. (1501 aa)
PTPRGProtein tyrosine phosphatase receptor type G. (1438 aa)
STK26Serine/threonine kinase 26. (410 aa)
MYOCDMyocardin. (976 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
C5Complement C5. (1678 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (504 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1078 aa)
STAP1Signal transducing adaptor family member 1. (288 aa)
GNA12G protein subunit alpha 12. (315 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
CERS2Ceramide synthase 2. (380 aa)
WDR63WD repeat domain 63. (879 aa)
SCAISuppressor of cancer cell invasion. (578 aa)
H0UW27_CAVPOSCY domain-containing protein. (109 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
ABCC8ATP binding cassette subfamily C member 8. (1549 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
ADAM15ADAM metallopeptidase domain 15. (862 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1084 aa)
NBL1NBL1, DAN family BMP antagonist. (178 aa)
CALRCalreticulin. (417 aa)
PTGER4Prostaglandin E2 receptor 4; Belongs to the G-protein coupled receptor 1 family. (487 aa)
AGERAdvanced glycosylation end-product specific receptor. (377 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
ENGEndoglin. (653 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (200 aa)
NRG1Neuregulin 1. (700 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
DPYSL3Dihydropyrimidinase like 3. (684 aa)
RIPOR2RHO family interacting cell polarization regulator 2. (1062 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1578 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
GPR18G protein-coupled receptor 18. (335 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
EMILIN1Elastin microfibril interfacer 1. (1017 aa)
ACANAggrecan. (2119 aa)
PTNPleiotrophin. (168 aa)
Srgap2Uncharacterized protein. (1063 aa)
IL24Interleukin 24. (216 aa)
CD63Tetraspanin. (238 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ADTRPAndrogen dependent TFPI regulating protein. (223 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
H0VFH9_CAVPOFibrinogen C-terminal domain-containing protein. (480 aa)
ROBO1Roundabout guidance receptor 1. (1612 aa)
VASH1Vasohibin 1. (368 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
LIMCH1LIM and calponin homology domains 1. (1072 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (486 aa)
PODNPodocan. (613 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (244 aa)
EPHA4EPH receptor A4. (986 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1455 aa)
LRCH1Leucine rich repeats and calponin homology domain containing 1. (642 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (891 aa)
GDF2Growth differentiation factor 2. (411 aa)
MARVELD3MARVEL domain containing 3. (388 aa)
NRG3Neuregulin 3. (600 aa)
TNNTenascin N. (1473 aa)
THY1Thy-1 protein. (161 aa)
APOHApolipoprotein H. (235 aa)
FLCNFolliculin. (579 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (504 aa)
DLC1DLC1 Rho GTPase activating protein. (1091 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (976 aa)
GNA13G protein subunit alpha 13. (377 aa)
MCCMCC regulator of WNT signaling pathway. (1009 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
MAPK15Mitogen-activated protein kinase. (539 aa)
IL27RAInterleukin 27 receptor subunit alpha. (641 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1395 aa)
TBX5T-box transcription factor 5. (518 aa)
THBS1Thrombospondin 1. (1163 aa)
NEXMIFNeurite extension and migration factor. (1510 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1237 aa)
NAV3Neuron navigator 3. (2086 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
GNRH1GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. (92 aa)
NODALNodal growth differentiation factor. (351 aa)
CARD10Caspase recruitment domain family member 10. (937 aa)
BCRBCR activator of RhoGEF and GTPase. (1227 aa)
SRFSerum response factor. (461 aa)
H0W027_CAVPOUncharacterized protein. (722 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
ADARB1Adenosine deaminase RNA specific B1. (603 aa)
PODNL1Podocan like 1. (608 aa)
H0W0Z8_CAVPOF-BAR domain-containing protein. (214 aa)
BCL2BCL2 apoptosis regulator. (183 aa)
LOC101788748Uncharacterized protein. (478 aa)
HRGHistidine rich glycoprotein. (467 aa)
Foxo3Forkhead box O3. (660 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (355 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
HAS1Hyaluronan synthase 1. (581 aa)
GSTP1Glutathione S-transferase pi 1. (210 aa)
NKX2-1Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis (By similarity). (344 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1623 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
Drd4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1137 aa)
Egfl7Uncharacterized protein. (154 aa)
FAM102BFamily with sequence similarity 102 member B. (360 aa)
IGFBP3Insulin like growth factor binding protein 3. (293 aa)
CCN3Cellular communication network factor 3. (356 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
CHRDChordin. (892 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (298 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
Ccl25SCY domain-containing protein. (145 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (479 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (967 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
ADAAdenosine deaminase. (365 aa)
NF1Neurofibromin 1. (2750 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
PTPRRProtein tyrosine phosphatase receptor type R. (657 aa)
CCL21C-C motif chemokine ligand 21. (126 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (114 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1864 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
HYAL2Hyaluronidase. (471 aa)
LOC100723644C-type lectin domain-containing protein. (222 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (211 aa)
RNF41Ring finger protein 41. (317 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1345 aa)
CD300ACD300a molecule. (309 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (210 aa)
SLIT2Slit guidance ligand 2. (1391 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (476 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
ANGPT2Angiopoietin 2. (494 aa)
KANK1KN motif and ankyrin repeat domains 1. (1353 aa)
STK24Serine/threonine kinase 24. (470 aa)
BMERB1BMERB domain containing 1. (204 aa)
LOC100722817C-type lectin domain-containing protein. (225 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
SERPINF1SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
MMP28Matrix metallopeptidase 28. (518 aa)
EPHA1EPH receptor A1. (979 aa)
GcsamUncharacterized protein. (157 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (252 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (306 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1311 aa)
TRIB1Tribbles pseudokinase 1. (323 aa)
SLURP1Secreted LY6/PLAUR domain containing 1. (96 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
LRP1LDL receptor related protein 1. (4508 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (172 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1084 aa)
CD74CD74 molecule. (280 aa)
SINHCAFSIN3-HDAC complex associated factor. (221 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (579 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IGFBP5Insulin like growth factor binding protein 5. (271 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
ABRABR activator of RhoGEF and GTPase. (859 aa)
DAG1Dystroglycan 1. (891 aa)
MIIPMigration and invasion inhibitory protein. (383 aa)
LOC100727246Uncharacterized protein. (226 aa)
ZMYND8Zinc finger MYND-type containing 8. (1213 aa)
ENSCPOP00000026444Uncharacterized protein. (171 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (470 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)
DACH1Dachshund family transcription factor 1. (750 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (420 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (764 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (247 aa)
SFRP1Secreted frizzled related protein 1. (307 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
ENSCPOP00000027386Uncharacterized protein. (234 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
SLAMF8SLAM family member 8. (279 aa)
NDRG4NDRG family member 4. (404 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (591 aa)
ADORA3Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (323 aa)
DAB2IPDAB2 interacting protein. (1193 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (396 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (540 aa)
AFDNAfadin, adherens junction formation factor. (1794 aa)
RRASRAS related. (218 aa)
CD200CD200 molecule. (268 aa)
STC1Stanniocalcin 1. (247 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
ARID2AT-rich interaction domain 2. (1763 aa)
LOC100735277Ig-like domain-containing protein. (351 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (326 aa)
SVBPSmall vasohibin binding protein. (66 aa)
PFN2Profilin; Belongs to the profilin family. (140 aa)
S1PR2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
TCAF1TRPM8 channel associated factor 1. (921 aa)
CLASP1Cytoplasmic linker associated protein 1. (1524 aa)
TAFA5TAFA chemokine like family member 5. (125 aa)
Clasp2Uncharacterized protein. (1497 aa)
STARD13StAR related lipid transfer domain containing 13. (1109 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1445 aa)
GREM1Gremlin. (184 aa)
ENSCPOP00000030875ARID domain-containing protein. (504 aa)
FASFas cell surface death receptor. (334 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (447 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1504 aa)
PDCD10Programmed cell death 10. (212 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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