22 items (Cavia porcellus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	FASN	Fatty acid synthase. (2530 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (865 aa)
	IL17C	Interleukin 17C. (189 aa)
	L3MBTL3	L3MBTL histone methyl-lysine binding protein 3. (779 aa)
	LEF1	Lymphoid enhancer binding factor 1. (396 aa)
	Lbr	Tudor domain-containing protein. (133 aa)
	DHRS7B	Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
	CBFA2T3	CBFA2/RUNX1 partner transcriptional co-repressor 3. (614 aa)
	Cebpa	Uncharacterized protein. (158 aa)
	CSF2	Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (145 aa)
	SPI1	Spi-1 proto-oncogene. (258 aa)
	ZFPM1	Zinc finger protein, FOG family member 1. (876 aa)
	CEBPE	CCAAT/enhancer-binding protein. (281 aa)
	GATA2	GATA binding protein 2. (374 aa)
	GATA1	GATA binding protein 1. (401 aa)
	IL25	Interleukin 25. (168 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (503 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (269 aa)
	BAP1	Ubiquitin carboxyl-terminal hydrolase. (729 aa)
	SP3	Sp3 transcription factor. (690 aa)
	ZBTB46	Zinc finger and BTB domain containing 46. (599 aa)
	AP3B1	Adaptor related protein complex 3 subunit beta 1. (1276 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAP1	KDM1A	ENSCPOP00000002935	ENSCPOP00000030158	Ubiquitin carboxyl-terminal hydrolase.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.571
CBFA2T3	CEBPE	ENSCPOP00000020206	ENSCPOP00000012653	CBFA2/RUNX1 partner transcriptional co-repressor 3.	CCAAT/enhancer-binding protein.	0.660
CBFA2T3	Cebpa	ENSCPOP00000020206	ENSCPOP00000015836	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Uncharacterized protein.	0.660
CBFA2T3	DHRS7B	ENSCPOP00000020206	ENSCPOP00000022078	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.400
CBFA2T3	FASN	ENSCPOP00000020206	ENSCPOP00000002086	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Fatty acid synthase.	0.666
CBFA2T3	GATA1	ENSCPOP00000020206	ENSCPOP00000006830	CBFA2/RUNX1 partner transcriptional co-repressor 3.	GATA binding protein 1.	0.591
CBFA2T3	KDM1A	ENSCPOP00000020206	ENSCPOP00000030158	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.487
CBFA2T3	Lbr	ENSCPOP00000020206	ENSCPOP00000022925	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Tudor domain-containing protein.	0.553
CBFA2T3	SPI1	ENSCPOP00000020206	ENSCPOP00000015005	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Spi-1 proto-oncogene.	0.780
CEBPE	CBFA2T3	ENSCPOP00000012653	ENSCPOP00000020206	CCAAT/enhancer-binding protein.	CBFA2/RUNX1 partner transcriptional co-repressor 3.	0.660
CEBPE	Cebpa	ENSCPOP00000012653	ENSCPOP00000015836	CCAAT/enhancer-binding protein.	Uncharacterized protein.	0.612
CEBPE	GATA1	ENSCPOP00000012653	ENSCPOP00000006830	CCAAT/enhancer-binding protein.	GATA binding protein 1.	0.510
CEBPE	GATA2	ENSCPOP00000012653	ENSCPOP00000008799	CCAAT/enhancer-binding protein.	GATA binding protein 2.	0.480
CEBPE	LEF1	ENSCPOP00000012653	ENSCPOP00000023567	CCAAT/enhancer-binding protein.	Lymphoid enhancer binding factor 1.	0.442
CEBPE	SPI1	ENSCPOP00000012653	ENSCPOP00000015005	CCAAT/enhancer-binding protein.	Spi-1 proto-oncogene.	0.649
Cebpa	CBFA2T3	ENSCPOP00000015836	ENSCPOP00000020206	Uncharacterized protein.	CBFA2/RUNX1 partner transcriptional co-repressor 3.	0.660
Cebpa	CEBPE	ENSCPOP00000015836	ENSCPOP00000012653	Uncharacterized protein.	CCAAT/enhancer-binding protein.	0.612
Cebpa	GATA1	ENSCPOP00000015836	ENSCPOP00000006830	Uncharacterized protein.	GATA binding protein 1.	0.443
Cebpa	GATA2	ENSCPOP00000015836	ENSCPOP00000008799	Uncharacterized protein.	GATA binding protein 2.	0.621
Cebpa	LEF1	ENSCPOP00000015836	ENSCPOP00000023567	Uncharacterized protein.	Lymphoid enhancer binding factor 1.	0.450