STRINGSTRING
DNAJC9 DNAJC9 DNAJC7 DNAJC7 DNAJC18 DNAJC18 Spn Spn MVD MVD METTL18 METTL18 STUB1 STUB1 TTC4 TTC4 TPR TPR LOC100717205 LOC100717205 HIKESHI HIKESHI CREB1 CREB1 TOMM34 TOMM34 FKBP5 FKBP5 GMEB1 GMEB1 METTL22 METTL22 ENSCPOP00000023134 ENSCPOP00000023134 STIP1 STIP1 PPP5C PPP5C ARNTL ARNTL DNAJB9 DNAJB9 ENSCPOP00000024193 ENSCPOP00000024193 CYP2E1 CYP2E1 HTT HTT FICD FICD ZFP36 ZFP36 CDC37 CDC37 TRANK1 TRANK1 GPR37 GPR37 NUP62 NUP62 HSPA14 HSPA14 DNAJA3 DNAJA3 ENSCPOP00000032931 ENSCPOP00000032931 DMP1 DMP1 CAMKMT CAMKMT TELO2 TELO2 TSC2 TSC2 FKBP4 FKBP4 SSUH2 SSUH2 HSPA9 HSPA9 St13 St13 ITGAM ITGAM DNAJB14 DNAJB14 KPNB1 KPNB1 HSPA2 HSPA2 SNCA SNCA TFRC TFRC ENSCPOP00000027159 ENSCPOP00000027159 LOC100726317 LOC100726317 UNC45A UNC45A DNAJB12 DNAJB12 DNAJA4 DNAJA4 CYP27A1 CYP27A1 FAF1 FAF1 PPID PPID KSR1 KSR1 LIMK1 LIMK1 ERN1 ERN1 Dnaja1 Dnaja1 BAK1 BAK1 USP19 USP19 H0VH67_CAVPO H0VH67_CAVPO DNAJB1 DNAJB1 CDC37L1 CDC37L1 ULK1 ULK1 PDXP PDXP Rps3 Rps3 CHORDC1 CHORDC1 ENSCPOP00000029129 ENSCPOP00000029129 BAG2 BAG2 TFAM TFAM PTGES3 PTGES3 ENSCPOP00000029431 ENSCPOP00000029431 BAG6 BAG6 DNAJC8 DNAJC8 ENSCPOP00000030021 ENSCPOP00000030021 HSPA6 HSPA6 CDKN1B CDKN1B UNC45B UNC45B EEF1AKMT3 EEF1AKMT3 TSC1 TSC1 Ahsa2p Ahsa2p Cdk1 Cdk1 HIF1A HIF1A H0V4H8_CAVPO H0V4H8_CAVPO PACRG PACRG EIF2AK3 EIF2AK3 Mapt Mapt CDK5 CDK5 ENSCPOP00000032487 ENSCPOP00000032487 APOA1 APOA1 NOD2 NOD2 ENSCPOP00000032121 ENSCPOP00000032121 HDAC2 HDAC2 NFKBIA NFKBIA Ahr Ahr CLTC CLTC Hdac8 Hdac8 PACRGL PACRGL DNAJC10 DNAJC10 ENSCPOP00000030888 ENSCPOP00000030888 SACS SACS Pttg1 Pttg1 ENSCPOP00000031515 ENSCPOP00000031515 ATF5 ATF5 BAX BAX HSF1 HSF1 IRAK1 IRAK1 SLC12A2 SLC12A2 GUCY1B1 GUCY1B1 STAU2 STAU2 AHSA1 AHSA1 PTGES3L PTGES3L Dnaja2 Dnaja2 IQCG IQCG PPEF2 PPEF2 NFKB1 NFKB1 HSPA13 HSPA13 DNAJC2 DNAJC2 APAF1 APAF1 CCDC39 CCDC39 APOA2 APOA2 CYP1A1 CYP1A1 NR3C1 NR3C1 METTL21A METTL21A METTL21C METTL21C Fkbp1a Fkbp1a HDAC6 HDAC6 DNAJB2 DNAJB2 HSPA8 HSPA8 LMAN2 LMAN2 ETFBKMT ETFBKMT BCOR BCOR SLC18A2 SLC18A2 H0V0N7_CAVPO H0V0N7_CAVPO ITGB2 ITGB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNAJC9DnaJ heat shock protein family (Hsp40) member C9. (260 aa)
DNAJC7DnaJ heat shock protein family (Hsp40) member C7. (493 aa)
DNAJC18DnaJ heat shock protein family (Hsp40) member C18. (358 aa)
SpnUncharacterized protein. (375 aa)
MVDDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
METTL18Methyltransferase like 18. (373 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
TTC4Tetratricopeptide repeat domain 4. (388 aa)
TPRTranslocated promoter region, nuclear basket protein. (2320 aa)
LOC100717205Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
HIKESHIHeat shock protein nuclear import factor hikeshi. (196 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TOMM34Translocase of outer mitochondrial membrane 34. (309 aa)
FKBP5Peptidylprolyl isomerase. (456 aa)
GMEB1Glucocorticoid modulatory element binding protein 1. (564 aa)
METTL22Methyltransferase like 22. (401 aa)
ENSCPOP00000023134DRBM domain-containing protein. (120 aa)
STIP1Stress induced phosphoprotein 1. (543 aa)
PPP5CSerine/threonine-protein phosphatase. (533 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (222 aa)
ENSCPOP00000024193Uncharacterized protein. (355 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (496 aa)
HTTHuntingtin. (3133 aa)
FICDFIC domain containing. (458 aa)
ZFP36ZFP36 ring finger protein. (313 aa)
CDC37Cell division cycle 37. (378 aa)
TRANK1Tetratricopeptide repeat and ankyrin repeat containing 1. (2905 aa)
GPR37G protein-coupled receptor 37. (606 aa)
NUP62Nucleoporin 62. (518 aa)
HSPA14Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family. (509 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (479 aa)
ENSCPOP00000032931CR-type domain-containing protein. (379 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (494 aa)
CAMKMTCalmodulin-lysine N-methyltransferase. (323 aa)
TELO2Telomere maintenance 2. (737 aa)
TSC2TSC complex subunit 2. (1745 aa)
FKBP4Peptidylprolyl isomerase. (458 aa)
SSUH2Ssu-2 homolog. (328 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (678 aa)
St13TPR_REGION domain-containing protein. (365 aa)
ITGAMIntegrin alpha-M; Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated act [...] (1123 aa)
DNAJB14DnaJ heat shock protein family (Hsp40) member B14. (379 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (620 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
TFRCTransferrin receptor protein 1. (765 aa)
ENSCPOP00000027159TPR_REGION domain-containing protein. (226 aa)
LOC100726317Uncharacterized protein. (421 aa)
UNC45AUnc-45 myosin chaperone A. (944 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (378 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (397 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (566 aa)
FAF1Fas associated factor 1. (555 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
KSR1Kinase suppressor of ras 1. (879 aa)
LIMK1LIM domain kinase 1. (646 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (974 aa)
Dnaja1Uncharacterized protein. (397 aa)
BAK1BCL2 antagonist/killer 1. (214 aa)
USP19Ubiquitin specific peptidase 19. (1355 aa)
H0VH67_CAVPOANK_REP_REGION domain-containing protein. (159 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (339 aa)
CDC37L1Cell division cycle 37 like 1. (339 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1037 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (292 aa)
Rps3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
CHORDC1Cysteine and histidine rich domain containing 1. (332 aa)
ENSCPOP00000029129Protein kinase domain-containing protein. (254 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
TFAMTranscription factor A, mitochondrial. (235 aa)
PTGES3Prostaglandin E synthase 3. (160 aa)
ENSCPOP00000029431Uncharacterized protein. (111 aa)
BAG6BCL2 associated athanogene 6. (1169 aa)
DNAJC8DnaJ heat shock protein family (Hsp40) member C8. (253 aa)
ENSCPOP00000030021Uncharacterized protein; Belongs to the heat shock protein 70 family. (537 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
UNC45BUnc-45 myosin chaperone B. (929 aa)
EEF1AKMT3EEF1A lysine methyltransferase 3. (231 aa)
TSC1TSC complex subunit 1. (1166 aa)
Ahsa2pAha1_N domain-containing protein. (331 aa)
Cdk1Protein kinase domain-containing protein. (240 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (828 aa)
H0V4H8_CAVPOKH domain-containing protein. (145 aa)
PACRGParkin coregulated. (241 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1112 aa)
MaptMicrotubule-associated protein. (370 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ENSCPOP00000032487HipN domain-containing protein. (121 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (264 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1018 aa)
ENSCPOP00000032121Uncharacterized protein. (213 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
AhrUncharacterized protein. (832 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
Hdac8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa)
PACRGLParkin coregulated like. (251 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (792 aa)
ENSCPOP00000030888Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (238 aa)
SACSSacsin molecular chaperone. (4542 aa)
Pttg1Uncharacterized protein. (198 aa)
ENSCPOP00000031515Uncharacterized protein. (406 aa)
ATF5Activating transcription factor 5. (279 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
HSF1Heat shock transcription factor 1. (555 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
SLC12A2Solute carrier family 12 member 2. (1136 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (622 aa)
STAU2Staufen double-stranded RNA binding protein 2. (570 aa)
AHSA1Activator of HSP90 ATPase activity 1. (338 aa)
PTGES3LProstaglandin E synthase 3 like. (149 aa)
Dnaja2Uncharacterized protein. (412 aa)
IQCGIQ motif containing G. (405 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (733 aa)
NFKB1Nuclear factor kappa B subunit 1. (967 aa)
HSPA13Heat shock protein family A (Hsp70) member 13. (394 aa)
DNAJC2DnaJ heat shock protein family (Hsp40) member C2. (604 aa)
APAF1Apoptotic peptidase activating factor 1. (1265 aa)
CCDC39Coiled-coil domain containing 39. (678 aa)
APOA2Apolipoprotein A2. (101 aa)
CYP1A1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (516 aa)
NR3C1Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (772 aa)
METTL21AMethyltransferase like 21A. (218 aa)
METTL21CMethyltransferase like 21C. (264 aa)
Fkbp1aPeptidylprolyl isomerase. (108 aa)
HDAC6Histone deacetylase 6. (1196 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (278 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
LMAN2Lectin, mannose binding 2. (356 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (254 aa)
BCORBCL6 corepressor. (1758 aa)
SLC18A2Solute carrier family 18 member A2. (516 aa)
H0V0N7_CAVPOPeptidylprolyl isomerase. (204 aa)
ITGB2Integrin beta. (767 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (14%) [HD]