28 items (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCPOP00000023438	Uncharacterized protein. (283 aa)
	ENSCPOP00000023932	Uncharacterized protein. (332 aa)
	Cetn2	Uncharacterized protein. (172 aa)
	GNAO1	G protein subunit alpha o1. (318 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa)
	GNAT3	G protein subunit alpha transducin 3. (354 aa)
	CETN1	Centrin 1. (172 aa)
	H0W9J0_CAVPO	Uncharacterized protein. (147 aa)
	GNA11	G protein subunit alpha 11. (345 aa)
	GNAI2	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. (355 aa)
	GNAQ	G protein subunit alpha q. (313 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
	GNAI1	Uncharacterized protein. (330 aa)
	CETN3	Centrin 3. (163 aa)
	LOC100732436	Uncharacterized protein. (327 aa)
	GNA14	G protein subunit alpha 14. (356 aa)
	Gna15	Uncharacterized protein. (205 aa)
	GNAL	G protein subunit alpha L. (372 aa)
	GNA12	G protein subunit alpha 12. (315 aa)
	H0VE70_CAVPO	Uncharacterized protein. (796 aa)
	LOC100732158	Uncharacterized protein. (246 aa)
	ENSCPOP00000022087	Uncharacterized protein. (161 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
	GNAT1	Alpha-transducin. (350 aa)
	GNAI3	Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...] (354 aa)
	Gnat2	Uncharacterized protein. (354 aa)
	GNAZ	G protein subunit alpha z. (355 aa)

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY2	ADCY4	ENSCPOP00000009680	ENSCPOP00000012980	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.691
ADCY2	ENSCPOP00000023932	ENSCPOP00000009680	ENSCPOP00000023932	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.600
ADCY2	GNA12	ENSCPOP00000009680	ENSCPOP00000001605	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha 12.	0.546
ADCY2	GNA13	ENSCPOP00000009680	ENSCPOP00000011766	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha 13.	0.584
ADCY2	GNAI1	ENSCPOP00000009680	ENSCPOP00000030063	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.874
ADCY2	GNAI2	ENSCPOP00000009680	ENSCPOP00000025341	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily.	0.937
ADCY2	GNAI3	ENSCPOP00000009680	ENSCPOP00000010346	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(i) subunit alpha; Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modul [...]	0.938
ADCY2	GNAL	ENSCPOP00000009680	ENSCPOP00000002727	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha L.	0.975
ADCY2	GNAO1	ENSCPOP00000009680	ENSCPOP00000024931	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha o1.	0.888
ADCY2	GNAT1	ENSCPOP00000009680	ENSCPOP00000007345	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Alpha-transducin.	0.600
ADCY2	GNAT3	ENSCPOP00000009680	ENSCPOP00000014659	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha transducin 3.	0.699
ADCY2	GNAZ	ENSCPOP00000009680	ENSCPOP00000022400	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha z.	0.699
ADCY2	Gnat2	ENSCPOP00000009680	ENSCPOP00000010358	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.600
ADCY2	H0VE70_CAVPO	ENSCPOP00000009680	ENSCPOP00000008303	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.916
ADCY2	LOC100732158	ENSCPOP00000009680	ENSCPOP00000021644	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.796
ADCY2	LOC100732436	ENSCPOP00000009680	ENSCPOP00000031430	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.975
ADCY4	ADCY2	ENSCPOP00000012980	ENSCPOP00000009680	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.691
ADCY4	ENSCPOP00000023932	ENSCPOP00000012980	ENSCPOP00000023932	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.600
ADCY4	GNA12	ENSCPOP00000012980	ENSCPOP00000001605	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha 12.	0.546
ADCY4	GNA13	ENSCPOP00000012980	ENSCPOP00000011766	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha 13.	0.549