STRINGSTRING
TYK2 TYK2 JAK2 JAK2 EDNRB EDNRB BDKRB2 BDKRB2 AGT AGT ARRB1 ARRB1 DRD1 DRD1 ARAP1 ARAP1 ARRB2 ARRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TYK2Tyrosine-protein kinase. (1174 aa)
JAK2Tyrosine-protein kinase. (1035 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (415 aa)
BDKRB2B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (399 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
ARRB1Arrestin beta 1. (430 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (444 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1475 aa)
ARRB2Arrestin beta 2. (417 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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