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| | FAM83D | Family with sequence similarity 83 member D. (585 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | WAC | WW domain containing adaptor with coiled-coil. (632 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1471 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (435 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (228 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (121 aa) |
| | Castor2 | Uncharacterized protein. (356 aa) |
| | ENSCPOP00000028708 | Uncharacterized protein. (153 aa) |
| | WDR59 | WD repeat domain 59. (983 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (418 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (165 aa) |
| | DGKQ | Diacylglycerol kinase. (947 aa) |
| | TBC1D7 | TBC1 domain family member 7. (293 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | UBR1 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1736 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (474 aa) |
| | SMCR8 | SMCR8-C9orf72 complex subunit. (936 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1111 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | GPR137C | G protein-coupled receptor 137C. (424 aa) |
| | GAS6 | Growth arrest specific 6. (678 aa) |
| | TMEM127 | Transmembrane protein 127. (238 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (917 aa) |
| | SZT2 | SZT2 subunit of KICSTOR complex. (3427 aa) |
| | Depdc5 | DEP domain-containing protein. (1576 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4024 aa) |
| | KPTN | Kaptin, actin binding protein. (435 aa) |
| | TMEM130 | Transmembrane protein 130. (345 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3031 aa) |
| | RRAGB | Ras related GTP binding B. (362 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | SLC38A9 | Solute carrier family 38 member 9. (559 aa) |
| | MIOS | Meiosis regulator for oocyte development. (875 aa) |
| | LARS1 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1174 aa) |
| | FLCN | Folliculin. (579 aa) |
| | GPR137B | G protein-coupled receptor 137B. (385 aa) |
| | TTI1 | TELO2 interacting protein 1. (1089 aa) |
| | H0VMR0_CAVPO | Tyrosine-protein kinase receptor. (625 aa) |
| | Lamtor4 | Uncharacterized protein. (99 aa) |
| | DEPTOR | DEP domain containing MTOR interacting protein. (403 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (828 aa) |
| | TSC1 | TSC complex subunit 1. (1166 aa) |
| | RRAGD | Ras related GTP binding D. (348 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (229 aa) |
| | TELO2 | Telomere maintenance 2. (737 aa) |
| | TSC2 | TSC complex subunit 2. (1745 aa) |
| | GBA | Glucosylceramidase. (516 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (582 aa) |
| | CRYBA1 | Beta A3-crystallin; Belongs to the beta/gamma-crystallin family. (215 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | RHEB | Uncharacterized protein. (184 aa) |
| | GOLPH3 | Golgi phosphoprotein 3. (298 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2558 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1049 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | RELN | Reelin. (3423 aa) |
| | MTM1 | Myotubularin 1. (599 aa) |
| | GPR137 | G protein-coupled receptor 137. (396 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1164 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (193 aa) |
| | HTR6 | 5-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (437 aa) |
| | GNA12 | G protein subunit alpha 12. (315 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa) |
| | FBXO9 | F-box protein 9. (438 aa) |
| | SIRT1 | Sirtuin 1. (717 aa) |
| | SESN2 | Sestrin 2. (480 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa) |
| | SIK3 | SIK family kinase 3. (1275 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | OTUD5 | OTU deubiquitinase 5. (571 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (444 aa) |
| | TBCK | TBC1 domain containing kinase. (893 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator like. (626 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | C12orf66 | Chromosome 12 open reading frame 66. (445 aa) |
| | SESN1 | Sestrin 1. (564 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (381 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (423 aa) |
| | CASTOR1 | Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa) |
| | GPAT3 | Glycerol-3-phosphate acyltransferase 3. (437 aa) |
| | WDR24 | WD repeat domain 24. (790 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (470 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (322 aa) |
| | KLHL22 | Kelch like family member 22. (639 aa) |
| | RRAGA | Ras related GTP binding A. (313 aa) |
| | Lin28a | CCHC-type domain-containing protein. (147 aa) |
| | SESN3 | Sestrin 3. (414 aa) |
| | H0W444_CAVPO | Uncharacterized protein. (91 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (319 aa) |
| | PDCD6 | Programmed cell death 6. (189 aa) |
| | AKT1S1 | AKT1 substrate 1. (282 aa) |
| | RNF167 | Ring finger protein 167. (346 aa) |
| | SH3BP4 | SH3 domain binding protein 4. (964 aa) |
| | LOC100723124 | CCHC-type domain-containing protein. (209 aa) |
| | ENDOG | Endonuclease. (299 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (470 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
