STRINGSTRING
BMP6 BMP6 KCNC2 KCNC2 SMPD3 SMPD3 Ank3 Ank3 RYR2 RYR2 CCND1 CCND1 SNCA SNCA MDM2 MDM2 CD14 CD14 KCNJ1 KCNJ1 CNGA3 CNGA3 ENPP1 ENPP1 KCNIP3 KCNIP3 THBS1 THBS1 PLCG2 PLCG2 TNFRSF11B TNFRSF11B ENTPD6 ENTPD6 SLC41A1 SLC41A1 FGF23 FGF23 ABCC6 ABCC6 KCNA1 KCNA1 SLC34A1 SLC34A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP6Bone morphogenetic protein 6. (505 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (418 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
Ank3Uncharacterized protein. (1948 aa)
RYR2Ryanodine receptor 2. (4910 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
CD14CD14 molecule. (395 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (376 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (647 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (900 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (256 aa)
THBS1Thrombospondin 1. (1163 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (400 aa)
ENTPD6Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (445 aa)
SLC41A1Solute carrier family 41 member 1. (514 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (257 aa)
ABCC6ATP binding cassette subfamily C member 6. (1436 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
SLC34A1Solute carrier family 34 member 1. (638 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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