STRINGSTRING
ATR ATR PCNA PCNA Mcm8 Mcm8 TREX1 TREX1 MSH2 MSH2 Mutyh Mutyh PMS2 PMS2 MSH6 MSH6 WRN WRN MLH1 MLH1 MCM9 MCM9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2539 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Mcm8MCM domain-containing protein; Belongs to the MCM family. (833 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
MutyhAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (530 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (890 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1336 aa)
WRNWRN RecQ like helicase. (1462 aa)
MLH1MutL homolog 1. (758 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1117 aa)
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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